I-TASSER results

I-TASSER results for job id Rv1802

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (463 residues)
MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQS
SGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLA
ATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLAT
QGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLG
LGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGL
GSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLS
QMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQ
HWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG
Prediction	CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEHCCCCCCCCCCCCCCCCC
Conf.Score	9855589655555546799958999999999999999999999999999998668899899999999999999999999999999999999999999999868998999999999999999876777588999999999999999999999999999999985899999987888877655554445567777756668999999987555666554445554556776665555544555555555556666554555455545555455566666666666666666667777777778877775555688887677788888777788777777778887888888888888888888888888888888888888888877888877778877788875678899999867654444436867778899998668986689758898876678877789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG
Prediction	4300010000000101001000002100100230033022003001000000122300100000110011003001200220332032031000000001222231320220031001000000100000000202131240120002001111000110142322431233134623232222234222232232222133013202332232223222023202222322332221222233321212233223212122222222111112223232222211111221221121121121100001112113003020001111011213323221212312222312221111110121011111222131122221212323243244546537435404400330373264143243357205400540474110100103546443132354548
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEHCCCCCCCCCCCCCCCCC
MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG

2g38B

0.35

0.13

0.37

1.33

MUSTER

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5gaoE

0.20

0.14

0.68

1.06

dPPAS

----------------------------------------------------------------------------------------------------------------------------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAARAAAAAAAAAA-----------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

2g38B

0.32

0.12

0.37

1.76

dPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5gaoE

0.24

0.18

0.73

1.70

PPAS

--------------------------------------------------------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA--------------AAAAAAAAAAAA-----AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA--AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTKEAYKKLSQKFHGTKSNKK------------------------------------------

2g38B

0.32

0.12

0.37

3.43

wdPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

2d4yA

0.08

0.07

0.85

1.02

Env-PPAS

-------DAFITNQL------RGAQNQSSGLTTRYEQMSKIDNLLADKSSSLSGSLQSFFTSLQTLVSNAEPAARQALIGKAEGLVNQFKTTDQYLRDQDKQV--NIAIGSSVAQINNYAKQ--IANLNDQISRMTNDLLDQRDQLVSELNKIQGSTARQLAAVPSSADPTRTTVAYVDEAAGNIEIPEKLLNTFRSQDLDQTRNTLGQLALAFADAFNAQHTKGYDADGNKGKDFFSIGSPVVYSNSNNADKTVSLTAKVVDSTKVQATDYKIVFDGTDWQVTRTADNTTFTATKDADGKLEIDGLKVTVGTGAQKNSFLLKPVSNAIV-----DMNVKVTNEAEIAMASESKLSDNRNGQALLDLQNSNVVGGNKTF----------------------NDAYATLVSDVGN---KTSTLKTSSTTQANVVKQLY------KQQQS---------------

2g38B

0.35

0.13

0.37

1.78

wMUSTER

--FEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5gaoE

0.27

0.19

0.72

1.05

wPPAS

--------------------------AAAAAAAAAAAAAAAAAAAAAAAAAAAA----AAAAAAAAAAAA-----AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA----------AAAAAAAAA------AAAAAA----AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA---------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA----------------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTKEAYKKLSQKFHGTKSNKK------------------------------------------

2g38B

0.35

0.13

0.37

4.39

wPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

2g38B

0.35

0.13

0.37

4.09

dPPAS2

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.58

Estimated TM-score = 0.64±0.13

Estimated RMSD = 8.5±4.5Å

Download Model 2

C-score=-0.99

Download Model 3

C-score=-1.03

Download Model 4

C-score=-2.55

Download Model 5

C-score=-1.94

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5k3jA	0.365	6.96	0.071	0.572
2	1w07B	0.363	7.25	0.068	0.583
3	2g38B	0.359	1.11	0.312	0.365
4	3dinA	0.358	7.31	0.030	0.600
5	3ba6A	0.356	6.12	0.058	0.525
6	1n63B	0.356	7.54	0.062	0.613
7	3ixzA	0.354	6.20	0.046	0.525
8	1ffvB	0.352	7.62	0.052	0.611
9	1mhsA	0.352	5.74	0.046	0.486
10	1t3qB	0.347	7.93	0.039	0.628

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.06	3	3ar3A	PTY	Rep, Mult	144,147,151,155
2	0.04	2	1y66B	DIO	Rep, Mult	150,153,157
3	0.04	2	3r6yB	CA	Rep, Mult	112,135
4	0.04	2	1vd5A	GLY	Rep, Mult	116,132
5	0.04	2	2jstB	HLT	Rep, Mult	31,34,68
6	0.04	2	3ar3A	PTY	Rep, Mult	38,79,83,86,87
7	0.04	2	5absA	ZN	Rep, Mult	141,145
8	0.04	2	2eauA	PTY	Rep, Mult	40,43,76,80
9	0.02	1	3bwxA	CA	Rep, Mult	70,73
10	0.02	1	3c9iC	XE	Rep, Mult	109,112
11	0.02	1	3j000	PEV	Rep, Mult	31,32
12	0.02	1	4zzbA	XE	Rep, Mult	109,139,142,143
13	0.02	1	2g381	III	Rep, Mult	3,14,15,17,18,19,20,23,24,27,30,31,33,34,37,38,40,41,44,45,48,52,56,64,71,74,82,85,89,96,153,154,157,161,164,165
14	0.02	1	2x7aI	MG	Rep, Mult	119,123
15	0.02	1	2q67A	CA	Rep, Mult	103,104
16	0.02	1	1iowA	MG	Rep, Mult	9,11
17	0.02	1	3hd7F	GGG	Rep, Mult	113,116

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1rm6A	0.341	8.02	0.053	0.618	1.3.99.20	NA
2	0.060	1bxrA	0.342	7.27	0.048	0.559	6.3.5.5	83,163
3	0.060	1xmeA	0.344	6.72	0.058	0.529	1.9.3.1	NA
4	0.060	1mo7A	0.171	6.03	0.049	0.251	3.6.3.9	77
5	0.060	3b8eC	0.333	6.76	0.027	0.520	3.6.3.9	93,287
6	0.060	3cf4A	0.339	6.50	0.054	0.512	1.2.99.2	NA
7	0.060	1is2A	0.334	7.15	0.048	0.540	1.3.3.6	22
8	0.060	1t3qB	0.347	7.93	0.039	0.628	1.3.99.17	NA
9	0.060	1y791	0.345	7.24	0.035	0.564	3.4.15.5	NA
10	0.060	2fonB	0.362	7.27	0.058	0.583	1.3.3.6	NA
11	0.060	2occN	0.334	6.49	0.044	0.497	1.9.3.1	NA
12	0.060	1occA	0.335	6.53	0.047	0.501	1.9.3.1	NA
13	0.060	1n63B	0.356	7.54	0.062	0.613	1.2.99.2	NA
14	0.060	1h16A	0.344	7.31	0.060	0.575	2.3.1.54	NA
15	0.060	3b9jI	0.139	5.46	0.057	0.190	1.17.1.4,1.17.3.2	NA
16	0.060	1mhsA	0.352	5.74	0.046	0.486	3.6.3.6	NA
17	0.060	1w36B	0.332	6.76	0.056	0.520	3.1.11.5	22
18	0.060	1jrpB	0.335	7.88	0.050	0.598	1.17.1.4	145
19	0.060	1jroB	0.335	7.77	0.053	0.594	1.1.1.204	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.06	0.363	7.25	0.07	0.58	1w07B	GO:0000062 GO:0001676 GO:0003995 GO:0003997 GO:0005777 GO:0005829 GO:0006629 GO:0006631 GO:0006635 GO:0008152 GO:0009055 GO:0009506 GO:0009611 GO:0009620 GO:0009695 GO:0016491 GO:0016627 GO:0033539 GO:0046686 GO:0050660 GO:0052890 GO:0055088 GO:0055114
1	0.06	0.313	6.95	0.06	0.49	2z1qB	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
2	0.06	0.310	6.72	0.05	0.48	2uxwA	GO:0000062 GO:0001659 GO:0003995 GO:0004466 GO:0005634 GO:0005730 GO:0005737 GO:0005739 GO:0005743 GO:0005759 GO:0006629 GO:0006631 GO:0006635 GO:0008152 GO:0009055 GO:0015980 GO:0016020 GO:0016491 GO:0016627 GO:0017099 GO:0030855 GO:0033539 GO:0036498 GO:0042645 GO:0042760 GO:0045717 GO:0046322 GO:0050660 GO:0052890 GO:0055088 GO:0055114 GO:0090181
3	0.06	0.311	5.89	0.07	0.44	5j65A	GO:0030435
4	0.06	0.362	7.27	0.06	0.58	2fonB	GO:0000062 GO:0000166 GO:0003995 GO:0003997 GO:0005777 GO:0006631 GO:0006635 GO:0008152 GO:0009055 GO:0016627 GO:0033539 GO:0050660 GO:0052890 GO:0055088 GO:0055114
5	0.06	0.268	6.54	0.06	0.41	3mpiC	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0019439 GO:0050660 GO:0055114
6	0.06	0.334	7.15	0.05	0.54	1is2A	GO:0000062 GO:0003995 GO:0003997 GO:0005504 GO:0005777 GO:0006091 GO:0006629 GO:0006631 GO:0006635 GO:0006693 GO:0008152 GO:0009055 GO:0016401 GO:0016491 GO:0016627 GO:0019395 GO:0033539 GO:0033540 GO:0050660 GO:0052890 GO:0055088 GO:0055114
7	0.06	0.328	7.01	0.04	0.51	3owaC	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
8	0.06	0.263	7.00	0.07	0.43	5jscA	GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
9	0.06	0.264	6.35	0.06	0.40	1ivhA	GO:0000062 GO:0003995 GO:0005739 GO:0005759 GO:0006552 GO:0008152 GO:0008470 GO:0009055 GO:0009083 GO:0016491 GO:0016627 GO:0033539 GO:0050660 GO:0052890 GO:0055088 GO:0055114
10	0.06	0.256	6.51	0.04	0.40	1ukwA	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
11	0.06	0.265	6.99	0.05	0.43	4hr3A	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
12	0.06	0.257	6.65	0.03	0.40	3ii9C	GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
13	0.06	0.263	6.96	0.07	0.42	5iduC	GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
14	0.06	0.268	6.61	0.05	0.41	2ix6A	GO:0000062 GO:0003995 GO:0003997 GO:0005777 GO:0005829 GO:0006629 GO:0006631 GO:0006635 GO:0008152 GO:0009055 GO:0009514 GO:0009793 GO:0016491 GO:0016627 GO:0033539 GO:0046459 GO:0050660 GO:0052890 GO:0055088 GO:0055114
15	0.06	0.258	6.68	0.05	0.40	3swoA	GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
16	0.06	0.254	6.71	0.04	0.40	2pg0A	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
17	0.06	0.258	6.51	0.06	0.40	2ebaA	GO:0000166 GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114
18	0.06	0.256	6.85	0.03	0.41	3sf6A	GO:0003995 GO:0008152 GO:0016491 GO:0016627 GO:0050660 GO:0055114

Consensus prediction of GO terms

Molecular Function	GO:0050662	GO:0000166	GO:0016491	GO:1901681
GO-Score	0.46	0.46	0.46	0.36
Biological Processes	GO:0048878	GO:0006635
GO-Score	0.36	0.36
Cellular Component	GO:0005777	GO:0009506	GO:0042645	GO:0005730	GO:0005829	GO:0005743
GO-Score	0.12	0.06	0.06	0.06	0.06	0.06

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.