Threading Zmax Znorm MUSTER 26.07 4.49 dPPAS 71.86 7.73 wdPPAS 107.32 11.54 wMUSTER 36.22 6.25 wPPAS 92.94 13.28 dPPAS2 120.62 11.49 PPAS 75.86 10.84 Env-PPAS 11.02 1.38 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=2754) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.18 0.57+-0.15 11.6+-4.5 420 0.037 model2 -2.14 260 0.014 model3 -2.22 244 0.013 model4 -2.23 222 0.013 model5 -2.31 183 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).