Threading Zmax Znorm MUSTER 7.22 1.25 dPPAS 15.36 1.65 wdPPAS 16.32 1.76 wMUSTER 6.69 1.15 wPPAS 11.37 1.62 dPPAS2 30.60 2.91 PPAS 10.71 1.53 Env-PPAS 13.14 1.64 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=3012) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.75 0.62+-0.14 9.3+-4.6 1506 0.281 model2 -2.00 753 0.080 model3 -3.32 352 0.021 model4 -3.71 164 0.014 model5 -3.72 86 0.014 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).