I-TASSER results

I-TASSER results for job id Rv1753c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (1053 residues)
MNFSVLPPEINSALIFAGAGPEPMAAAATAWDGLAMELASAAASFGSVTSGLVGGAWQGA
SSSAMAAAAAPYAAWLAAAAVQAEQTAAQAAAMIAEFEAVKTAVVQPMLVAANRADLVSL
VMSNLFGQNAPAIAAIEATYEQMWAADVSAMSAYHAGASAIASALSPFSKPLQNLAGLPA
WLASGAPAAAMTAAAGIPALAGGPTAINLGIANVGGGNVGNANNGLANIGNANLGNYNFG
SGNFGNSNIGSASLGNNNIGFGNLGSNNVGVGNLGNLNTGFANTGLGNFGFGNTGNNNIG
IGLTGNNQIGIGGLNSGTGNFGLFNSGSGNVGFFNSGNGNFGIGNSGNFNTGGWNSGHGN
TGFFNAGSFNTGMLDVGNANTGSLNTGSYNMGDFNPGSSNTGTFNTGNANTGFLNAGNIN
TGVFNIGHMNNGLFNTGDMNNGVFYRGVGQGSLQFSITTPDLTLPPLQIPGISVPAFSLP
AITLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLN
IPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPA
NITVGAFSLPGLTLPSLNIPAATTPANITVSGFQLPPLSIPSVAIPPVTVPPITVGAFNL
PPLQIPEVTIPQLTIPAGITIGGFSLPAIHTQPITVGQIGVGQFGLPSIGWDVFLSTPRI
TVPAFGIPFTLQFQTNVPALQPPGGGLSTFTNGALIFGEFDLPQLVVHPYTLTGPIVIGS
FFLPAFNIPGIDVPAINVDGFTLPQITTPAITTPEFAIPPIGVGGFTLPQITTQEIITPE
LTINSIGVGGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIDPINLTG
FTLPQITTPPITTPPLTIEPIGVGGFTTPPLTVPGIHLPSTTIGAFAIPGGPGYFNSSTA
PSSGFFNSGAGGNSGFGNNGSGLSGWFNTNPAGLLGGSGYQNFGGLSSGFSNLGSGVSGF
ANRGILPFSVASVVSGFANIGTNLAGFFQGTTS

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MNFSVLPPEINSALIFAGAGPEPMAAAATAWDGLAMELASAAASFGSVTSGLVGGAWQGASSSAMAAAAAPYAAWLAAAAVQAEQTAAQAAAMIAEFEAVKTAVVQPMLVAANRADLVSLVMSNLFGQNAPAIAAIEATYEQMWAADVSAMSAYHAGASAIASALSPFSKPLQNLAGLPAWLASGAPAAAMTAAAGIPALAGGPTAINLGIANVGGGNVGNANNGLANIGNANLGNYNFGSGNFGNSNIGSASLGNNNIGFGNLGSNNVGVGNLGNLNTGFANTGLGNFGFGNTGNNNIGIGLTGNNQIGIGGLNSGTGNFGLFNSGSGNVGFFNSGNGNFGIGNSGNFNTGGWNSGHGNTGFFNAGSFNTGMLDVGNANTGSLNTGSYNMGDFNPGSSNTGTFNTGNANTGFLNAGNINTGVFNIGHMNNGLFNTGDMNNGVFYRGVGQGSLQFSITTPDLTLPPLQIPGISVPAFSLPAITLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVSGFQLPPLSIPSVAIPPVTVPPITVGAFNLPPLQIPEVTIPQLTIPAGITIGGFSLPAIHTQPITVGQIGVGQFGLPSIGWDVFLSTPRITVPAFGIPFTLQFQTNVPALQPPGGGLSTFTNGALIFGEFDLPQLVVHPYTLTGPIVIGSFFLPAFNIPGIDVPAINVDGFTLPQITTPAITTPEFAIPPIGVGGFTLPQITTQEIITPELTINSIGVGGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIEPIGVGGFTTPPLTVPGIHLPSTTIGAFAIPGGPGYFNSSTAPSSGFFNSGAGGNSGFGNNGSGLSGWFNTNPAGLLGGSGYQNFGGLSSGFSNLGSGVSGFANRGILPFSVASVVSGFANIGTNLAGFFQGTTS
Prediction	CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	986668864666445688986889999999999999999999999999887546778885799999999999999999999999999999999999999988768888888899999998875566765678888777777665455544445667888777778888888888888888887888888888888888888888888888888888888888888888888888888888888888888888888888988888889888888988898888998888888899989998889998999888899988888888998888888999999988899999999888999999988899889988899988998889999999988999989998899999999889999999888899999998888888988888888888888888888888899888899889988888888888888888899888888888998889888899888888888888888988888888998889988888888899888898888989999888899989998889988899888998888988889988899888998888988888988888888898888988899888998889988899888988888888888888999888898999999999999999888888889988899888998888888888888999999988898888888889988889988889888898889988899889998899998899888998888988899888998889988889888998899988999888988889988898888898888888899888998889988888888998889988888888998888988888888888888888899888888888888888888888888888899999998888889999887888898888888888888889887888888887888888888888888877888888765688999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MNFSVLPPEINSALIFAGAGPEPMAAAATAWDGLAMELASAAASFGSVTSGLVGGAWQGASSSAMAAAAAPYAAWLAAAAVQAEQTAAQAAAMIAEFEAVKTAVVQPMLVAANRADLVSLVMSNLFGQNAPAIAAIEATYEQMWAADVSAMSAYHAGASAIASALSPFSKPLQNLAGLPAWLASGAPAAAMTAAAGIPALAGGPTAINLGIANVGGGNVGNANNGLANIGNANLGNYNFGSGNFGNSNIGSASLGNNNIGFGNLGSNNVGVGNLGNLNTGFANTGLGNFGFGNTGNNNIGIGLTGNNQIGIGGLNSGTGNFGLFNSGSGNVGFFNSGNGNFGIGNSGNFNTGGWNSGHGNTGFFNAGSFNTGMLDVGNANTGSLNTGSYNMGDFNPGSSNTGTFNTGNANTGFLNAGNINTGVFNIGHMNNGLFNTGDMNNGVFYRGVGQGSLQFSITTPDLTLPPLQIPGISVPAFSLPAITLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVSGFQLPPLSIPSVAIPPVTVPPITVGAFNLPPLQIPEVTIPQLTIPAGITIGGFSLPAIHTQPITVGQIGVGQFGLPSIGWDVFLSTPRITVPAFGIPFTLQFQTNVPALQPPGGGLSTFTNGALIFGEFDLPQLVVHPYTLTGPIVIGSFFLPAFNIPGIDVPAINVDGFTLPQITTPAITTPEFAIPPIGVGGFTLPQITTQEIITPELTINSIGVGGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIEPIGVGGFTTPPLTVPGIHLPSTTIGAFAIPGGPGYFNSSTAPSSGFFNSGAGGNSGFGNNGSGLSGWFNTNPAGLLGGSGYQNFGGLSSGFSNLGSGVSGFANRGILPFSVASVVSGFANIGTNLAGFFQGTTS
Prediction	421001000100010100000000100010020002002100200100000000121101000000000000000011001102300320210000000001021221202101200010110000000000002002214324233110212133121122232222222322222232212221111111111212121111111222121222121132123221111111122122332312211132131221103213334121421313212122121221213211133121311114313122221213212132131431213312133130311313201122131331212214333131321112313132111231202212133120322312213131131421232211132210221242111120122112222122222221221214234242232323333233132332322221212312113131142422323232414223142241322214114332324243242421323114242142342241422414224242142422433424414234242142222334123222224243241422313113241232412323123241131422311112131334132242422223134241242312423213243334132241111314213233342411313123231132222323234141142313223233313124241142411424113243242422424124242242411323124142140412413113131231422413224142242322324133242341411323224221132313323224132141312323223121332434423324142231412323123231133332333322233221212232123121311201011111132231321110012211111221231100001111111111110010011221102124548
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980                1000                1020                1040

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Sec.Str
Seq

CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MNFSVLPPEINSALIFAGAGPEPMAAAATAWDGLAMELASAAASFGSVTSGLVGGAWQGASSSAMAAAAAPYAAWLAAAAVQAEQTAAQAAAMIAEFEAVKTAVVQPMLVAANRADLVSLVMSNLFGQNAPAIAAIEATYEQMWAADVSAMSAYHAGASAIASALSPFSKPLQNLAGLPAWLASGAPAAAMTAAAGIPALAGGPTAINLGIANVGGGNVGNANNGLANIGNANLGNYNFGSGNFGNSNIGSASLGNNNIGFGNLGSNNVGVGNLGNLNTGFANTGLGNFGFGNTGNNNIGIGLTGNNQIGIGGLNSGTGNFGLFNSGSGNVGFFNSGNGNFGIGNSGNFNTGGWNSGHGNTGFFNAGSFNTGMLDVGNANTGSLNTGSYNMGDFNPGSSNTGTFNTGNANTGFLNAGNINTGVFNIGHMNNGLFNTGDMNNGVFYRGVGQGSLQFSITTPDLTLPPLQIPGISVPAFSLPAITLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVSGFQLPPLSIPSVAIPPVTVPPITVGAFNLPPLQIPEVTIPQLTIPAGITIGGFSLPAIHTQPITVGQIGVGQFGLPSIGWDVFLSTPRITVPAFGIPFTLQFQTNVPALQPPGGGLSTFTNGALIFGEFDLPQLVVHPYTLTGPIVIGSFFLPAFNIPGIDVPAINVDGFTLPQITTPAITTPEFAIPPIGVGGFTLPQITTQEIITPELTINSIGVGGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIEPIGVGGFTTPPLTVPGIHLPSTTIGAFAIPGGPGYFNSSTAPSSGFFNSGAGGNSGFGNNGSGLSGWFNTNPAGLLGGSGYQNFGGLSSGFSNLGSGVSGFANRGILPFSVASVVSGFANIGTNLAGFFQGTTS

3gavA

0.08

0.98

2.00

MUSTER

LNPLRKPGDTPFGTFTLTGGN-------------VFEYGVKAV-YEINYRECDTDGWTNDIPICEVVK-APENGKIVSSAMEPDREYHFGQAV---FVCN--KIEGDEEMHDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYDEHFETPSGSYWDHIHCTQDSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSHPGYALPKAQTT-VTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYKLGYVTADGETSGSITCGKDGWSAQPT-CIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGEEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSQLEGNKRITCRNGQWSEPPKPCVISREIMENYNIALRWTAKQKLYSRTGESVEGYRLSSRS

3hr2A

0.11

0.10

0.85

2.84

dPPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGEGEGGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPGPQ-GARGLGTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSG----ENGTGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAGNGADGQGAKGANGAGIAGAGFGARGPSGPQPSGAGPKGTSGEGAGNKGDTGAKGEGPAGVQGPGPAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPAGPAGERGEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGPSGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQGDRGIGHRGFSGLQGPGSGSGEQGPSGASGPAGPRGPGSAGSGKDGLNGLGPIGGPRGRTGDS

2g38B

0.32

0.05

0.16

2.47

wdPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMD-AWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3hr2A

0.11

0.09

0.85

3.74

dPPAS2

-----------------------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGEGEGGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPGPQ-GARGLGTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSG----ENGTGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAG-NGADGQGAKGANGAGIAGAGFGARGPSGPQGPSGAGPKGTSGAGNKGDTGAKGEGPAGVQGPGPAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPAGPAGERGEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGPSGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQGDRGIGHRGFSGLQGPGSGSGEQGPSGASGPAGPRGPGSAGSGKDGLN----GLGPI--GGPR

2g38B

0.32

0.05

0.16

3.37

wPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLM-DAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3hr2A

0.12

0.10

0.85

3.40

PPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGEGEGGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPG-PQGARGLGTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSGENG-TGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAGN-GADGQGAKGANGAGIAGAGFGARGPSGPQGPSGAGPKGTSGEGAGNKGDTGAKGEGPAGVQGPG-PAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPAGPAGERGEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGPSGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQGDRGIGHRGFSGLQGPGSGSGEQGPSGASGPAGPRGPGSAGSGKDGLGLGPIGPRGR-DSGPA

2g38B

0.32

0.05

0.16

3.01

Env-PPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLM-DAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3gawA

0.07

0.98

2.00

MUSTER

LNPLRKPGDTPFGTFTLTGGN-------------VFEYGVKAV-YTINYRECDTDGWTNPICEVVKCLPVTAPGKIVSSAMEPDREYHFGQAV--RFV----KIEGDEEMHDDKEKPKCVEISSPISQKIIYKENERFQYK-YEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYYCDEHFETPSGSYWDHIHCTQDGSPAVPCLRKCYFPYLENGYNQNHGRKPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVENPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVELYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLY---SRTGESVEGYRLSSRS

3gavA

0.09

0.08

0.93

1.95

wMUSTER

LNPLRKPGDTPFGTFTLTGGN---------------EYGVKAV-YEINYRECDTDGWTND---------IP------------------------------VVKCLPVTAPEN---------GKIVSSAMEP----DREYH---FGQAVRFVGYKGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDERNGFYPATRGNTAKTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHITQDGWSPAVPCLRKCYFPYLENGQNHGRKFVQGKSHPGYALPKAQTTVTCMENGW-SPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYKLGYVTADGETSGSITCGKDGWSAQPT-CIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKEGEEIQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGER-RSPYEMFGDEENGNWTEPPQITSFPLSVYAPASSQNLYQLEGNKRIGIMENYNIALRWTAKQKLYSRTGESVEGYRLSSRS

3hr2B

0.10

0.09

0.86

2.82

dPPAS

-------------------------------------------------------------------------------------------------------------------------------------------------SDKGVSAGPGPMGLMGPRGPGAVGAGPQGFQGPAGEGEGQTGPAGSRGPAGPGKAGEDGHGKPGRGERGVVGPQGARGFGTGLGFGIRGHNGLDGLKGQGAQGVGEGAGENGTGQAGARGLGERGRVGAGPAGARGSDGSVGPVGPAGPIGSAGPGFGAGPGELGPVGNGPAGPAGPRGEAGLGLSGPVGPGNPGANGLTGAGATGLGVAGAGLGPRGIGPVGAAGATGPRGLVGEGPAGSGETGNKGEGSAGAQGPGPSGEEGKRGSPGEPGSAGPAGPGLRGSGSRGLGADGRAGVMGPPGNRGSTGPAGVRGPNGDAGRGEGLMGPRGLGSGNVGPAGKEGPVGLGIDGRGPIGPAGPRGEAGNIGFGPKGPSGDGKGEKGHPGLAGARGAGPDGNNGAQGPGPQGVQGGKGEQGPAGPGFQGLGPSGTAGEVGKGERGLPGEFGLGPAGPRGERGPGESGAAGPSGPIGIRGPSGAGPDGNKGEAGAVGAPGSAGASGPGGLGERGAAGIGGKGEKGETGLRGEIGNPGRDGARGAGAIGAGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGSAGQGAGEKGTKGPKGENGIVGPTGPVGAAGPSGPNGPPGPAGSRGDGGPPGMTGFGAAGRTGPGPSGITGPGPGAAGKEGIRGPRGDQGPVGRTGEIGASGPPGFAGEKGPSGEGTTGPGTAGPQGLLGAGILGLGSRGERGQGIAGALGEGPLGIAGPGARGPGAVGSGVNGAGEAGRDGNGSDGPGRDGQGHKGERGYGNIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDGARGLPGLKGHNGLQGLPGLAGLHGDQGAPGPVGPAGPRGPAGPSGPIGKDGRS

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 4 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.19

Estimated TM-score = 0.69±0.12

Estimated RMSD = 9.5±4.6Å

Download Model 2

C-score=-0.59

Download Model 3

C-score=-2.02

Download Model 4

C-score=-0.06

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3gavA	0.805	4.38	0.061	0.911
2	4i43B	0.246	8.77	0.039	0.372
3	1vw1A	0.243	9.31	0.038	0.382
4	3qmzA	0.230	9.21	0.036	0.359
5	3s4wA	0.219	9.75	0.030	0.362
6	3s4wB	0.219	9.49	0.039	0.351
7	4bedB	0.215	9.20	0.053	0.340
8	3jcrA	0.212	9.04	0.017	0.327
9	3bg5A	0.212	9.21	0.040	0.331
10	4o9xA	0.210	9.28	0.020	0.332

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	3	1k9jA	MAN	Rep, Mult	336,337
2	0.05	2	5bqtD	CA	Rep, Mult	94,98
3	0.02	1	1b2kB	IOD	Rep, Mult	1022,1026,1027
4	0.02	1	2i36C	UUU	Rep, Mult	1039,1046
5	0.02	1	3pcaM	DHB	Rep, Mult	8,15
6	0.02	1	1yf8B	UUU	Rep, Mult	205,296
7	0.02	1	4yfkC	4C6	Rep, Mult	34,38
8	0.02	1	2o01G	CLA	Rep, Mult	286,289
9	0.02	1	3usuA	UUU	Rep, Mult	324,325
10	0.02	1	1lyaD	UUU	Rep, Mult	257,258
11	0.02	1	2a0zA	UUU	Rep, Mult	266,283
12	0.02	1	3iylA	MYR	Rep, Mult	332,343
13	0.02	1	4ek2A	DA	Rep, Mult	199,200
14	0.02	1	2vsqA	LEU	Rep, Mult	295,313,316,317,335
15	0.02	1	3ee6A	CA	Rep, Mult	375,376,397,402,408,411
16	0.02	1	1nhcE	MAN	Rep, Mult	248,251
17	0.02	1	2bh1A	CA	Rep, Mult	30,32
18	0.02	1	2vn4A	MAN	Rep, Mult	346,347

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2vkzG	0.202	9.25	0.038	0.317	2.3.1.38,3.1.2.14	251
2	0.060	1kc7A	0.175	8.68	0.036	0.264	2.7.9.1	NA
3	0.060	1vbgA	0.177	8.91	0.040	0.272	2.7.9.1	NA
4	0.060	2vz8A	0.162	9.45	0.035	0.260	2.3.1.85	NA
5	0.060	2vumA	0.188	9.27	0.020	0.299	2.7.7.6	NA
6	0.060	3ecqB	0.189	9.14	0.037	0.295	3.2.1.97	249
7	0.060	2rhqB	0.168	8.33	0.038	0.249	6.1.1.20	250
8	0.060	1ynnJ	0.079	6.33	0.029	0.103	2.7.7.6	328,331
9	0.060	3ikmD	0.195	9.33	0.051	0.311	2.7.7.7	NA
10	0.060	3b8eA	0.150	9.53	0.029	0.242	3.6.3.9	NA
11	0.060	2pdaA	0.186	9.35	0.042	0.295	1.2.7.1	305,309,324
12	0.060	3lxuX	0.192	9.16	0.030	0.302	3.4.14.10	245,251
13	0.060	1mo7A	0.068	6.09	0.034	0.086	3.6.3.9	252
14	0.060	3ebgA	0.169	8.94	0.027	0.263	3.4.11.-	NA
15	0.060	3b8eC	0.157	8.50	0.024	0.231	3.6.3.9	455,457
16	0.060	3ffzA	0.167	8.61	0.045	0.249	3.4.24.69	NA
17	0.060	3c46B	0.162	9.23	0.028	0.256	2.7.7.6	255
18	0.060	2vz8B	0.201	9.26	0.046	0.317	2.3.1.85	341
19	0.060	2pffA	0.175	9.43	0.039	0.278	2.3.1.41,2.3.1.86	389

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.06	0.169	8.51	0.04	0.25	2gsxA	GO:0001618 GO:0001848 GO:0002376 GO:0002430 GO:0003677 GO:0004875 GO:0004888 GO:0005886 GO:0006955 GO:0006958 GO:0007165 GO:0016020 GO:0016021 GO:0016032 GO:0030183 GO:0042100 GO:0042803 GO:0043235 GO:0045087 GO:0046718 GO:0070062
1	0.06	0.194	8.95	0.03	0.30	3gauA	GO:0002376 GO:0005576 GO:0005615 GO:0006956 GO:0006957 GO:0008201 GO:0030449 GO:0043395 GO:0045087 GO:0070062 GO:0072562
2	0.06	0.164	8.50	0.02	0.24	4e0sB	GO:0001701 GO:0001970 GO:0002376 GO:0005576 GO:0005579 GO:0006955 GO:0006956 GO:0006958 GO:0019835 GO:0030449 GO:0045087 GO:0045766 GO:0045917 GO:0070062
3	0.06	0.134	9.11	0.02	0.21	4a5wB	GO:0001701 GO:0001970 GO:0002376 GO:0005576 GO:0005579 GO:0006955 GO:0006956 GO:0006958 GO:0019835 GO:0030449 GO:0045087 GO:0045766 GO:0045917 GO:0070062
4	0.06	0.148	9.12	0.01	0.23	3t5oA	GO:0001701 GO:0001970 GO:0002376 GO:0005576 GO:0005579 GO:0006955 GO:0006956 GO:0006958 GO:0019835 GO:0030449 GO:0045087 GO:0045766 GO:0045917 GO:0070062
5	0.06	0.115	5.84	0.07	0.14	1c1zA	GO:0001937 GO:0001948 GO:0002576 GO:0005543 GO:0005576 GO:0005615 GO:0005737 GO:0005886 GO:0006641 GO:0007568 GO:0007596 GO:0007597 GO:0008201 GO:0008289 GO:0009986 GO:0010596 GO:0010898 GO:0016525 GO:0030193 GO:0030194 GO:0030195 GO:0031012 GO:0031089 GO:0031100 GO:0031639 GO:0033033 GO:0034014 GO:0034197 GO:0034361 GO:0034364 GO:0034392 GO:0042627 GO:0042802 GO:0051006 GO:0051917 GO:0051918 GO:0060230 GO:0060268 GO:0070062
6	0.06	0.125	8.29	0.03	0.18	2xwbF	GO:0001848 GO:0002376 GO:0004252 GO:0005576 GO:0005615 GO:0005886 GO:0006508 GO:0006956 GO:0006957 GO:0008233 GO:0008236 GO:0016787 GO:0030449 GO:0045087 GO:0070062 GO:0072562
7	0.06	0.154	7.80	0.03	0.22	1ntlA	GO:0001701 GO:0002376 GO:0006958 GO:0007275 GO:0007565 GO:0009897 GO:0016020 GO:0016021 GO:0030449 GO:0043235 GO:0045087 GO:0045916
8	0.06	0.116	5.67	0.07	0.14	4kkdB	GO:0001867 GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0005615 GO:0006508 GO:0006898 GO:0006956 GO:0008233 GO:0008236 GO:0016787 GO:0042803 GO:0045087 GO:0045916 GO:0046872 GO:0048306
9	0.06	0.115	7.23	0.03	0.16	4aqbA	GO:0001867 GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0005615 GO:0006508 GO:0006898 GO:0006956 GO:0008233 GO:0008236 GO:0016787 GO:0042803 GO:0045087 GO:0045916 GO:0046872 GO:0048306
10	0.06	0.157	6.25	0.07	0.20	1ntjA	GO:0002376 GO:0006958 GO:0007275 GO:0007565 GO:0016020 GO:0016021 GO:0045087 GO:0045916
11	0.06	0.104	5.95	0.05	0.13	4c16A	GO:0002092 GO:0002523 GO:0004888 GO:0005615 GO:0005886 GO:0005901 GO:0005905 GO:0006954 GO:0007155 GO:0007157 GO:0007159 GO:0007202 GO:0016020 GO:0016021 GO:0019722 GO:0030029 GO:0030246 GO:0030863 GO:0032496 GO:0033691 GO:0034612 GO:0043274 GO:0045121 GO:0048471 GO:0050727 GO:0050900 GO:0050901 GO:0070492 GO:0070555
12	0.06	0.100	6.76	0.05	0.13	2atyA
13	0.06	0.104	6.87	0.03	0.14	4wqmA	GO:0008860 GO:0009055 GO:0016491 GO:0019439 GO:0042203 GO:0046872 GO:0051536 GO:0051537 GO:0055114
14	0.06	0.128	6.40	0.08	0.17	1gpzA	GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0006508 GO:0006955 GO:0006956 GO:0006958 GO:0008233 GO:0008236 GO:0016787 GO:0045087 GO:0070062 GO:0072562
15	0.06	0.133	6.64	0.08	0.17	4igdA	GO:0001867 GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0005615 GO:0006508 GO:0006898 GO:0006956 GO:0008233 GO:0008236 GO:0016787 GO:0042803 GO:0045087 GO:0045916 GO:0046872 GO:0048306
16	0.06	0.107	7.73	0.04	0.15	3vm5A	GO:0003824 GO:0004556 GO:0005975 GO:0008152 GO:0016787 GO:0016798 GO:0043169 GO:0046872
17	0.06	0.128	6.29	0.08	0.16	1zjkA	GO:0001855 GO:0001867 GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0006508 GO:0006956 GO:0006958 GO:0008233 GO:0008236 GO:0016787 GO:0045087 GO:0046872 GO:0048306 GO:0070062
18	0.06	0.118	5.35	0.09	0.14	3o8eB	GO:0001618 GO:0001669 GO:0001848 GO:0002079 GO:0002250 GO:0002376 GO:0002456 GO:0004175 GO:0004857 GO:0004872 GO:0005737 GO:0005794 GO:0005886 GO:0005887 GO:0005925 GO:0006508 GO:0006958 GO:0007338 GO:0008593 GO:0009986 GO:0010628 GO:0010629 GO:0016020 GO:0016021 GO:0016032 GO:0016323 GO:0030449 GO:0031410 GO:0032613 GO:0032733 GO:0035581 GO:0042102 GO:0043086 GO:0043382 GO:0045087 GO:0045296 GO:0045591 GO:0045916 GO:0046718 GO:0070062 GO:0071636

Consensus prediction of GO terms

Molecular Function	GO:0042803	GO:0001848	GO:0003677	GO:0043395	GO:0001618	GO:0004875	GO:0008201
GO-Score	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Biological Processes	GO:0002455	GO:0045765	GO:0043009	GO:1904018	GO:0001969	GO:0045917
GO-Score	0.45	0.35	0.35	0.35	0.35	0.35
Cellular Component	GO:1903561	GO:0031988	GO:0098797	GO:0046930	GO:0005887
GO-Score	0.55	0.55	0.35	0.35	0.35

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.