I-TASSER results

I-TASSER results for job id Rv1711

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (254 residues)
MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV
VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA
DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD
FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL
RSNEIGQLYQAVGL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVGL
Prediction	CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEHCCEEHCCCCEEHCCCCCEEEHCCEEHCCCCCEEEEEEHCCCCEEHCCCCCCCCCCEEEHCCCCCCCCCCEEHCCCCCCCCCCEEEEHCCHHHHHHHHCCCCCCCEEEEEEEHCCCCHHHHHHHHHCCEHCCEEEEEEEEEEEHCCCCEEEEEEEEHCCCCHHHHHHHHHHCCEEEEEEEEEHCCCCCCCCCCCEEHCCCHHHHHHHHHHHCC
Conf.Score	99888888887655799999996997799999999989879899996788856577885999999984788885899996999778677789999847864774547888768767888888865787578899998768788998699999968999999999997975589887557999985689869999999679868999999998995889899998476679989987775999999999999899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVGL
Prediction	74555776876421101200040030024303510663403033430542444043750403034540537542000000224100002517762400001035537344200001303430200000032340031002254715120203064504772053036105047340312303314757541201000211342102200521616044423020030417705444225025600530272178
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEHCCEEHCCCCEEHCCCCCEEEHCCEEHCCCCCEEEEEEHCCCCEEHCCCCCCCCCCEEEHCCCCCCCCCCEEHCCCCCCCCCCEEEEHCCHHHHHHHHCCCCCCCEEEEEEEHCCCCHHHHHHHHHCCEHCCEEEEEEEEEEEHCCCCEEEEEEEEHCCCCHHHHHHHHHHCCEEEEEEEEEHCCCCCCCCCCCEEHCCCHHHHHHHHHHHCC
MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVGL

3dh3B

0.34

0.31

0.92

5.10

MUSTER

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPF----VFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

10.41

dPPAS

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPF----VFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

10.27

wdPPAS

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKE----APFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

5.60

wMUSTER

----------DSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPF----VFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

5.29

wPPAS

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKE----APFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

9.89

dPPAS2

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKE----APFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

5.19

PPAS

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKE----APFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

3dh3B

0.34

0.31

0.92

6.89

Env-PPAS

---------PDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRAT-IGDQVKPG-DVVKVNGQLIEPREDLVLIALNKPVGIVSTTEDG-ERDNIVDFVNH----SKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPILGTVTKKCKVKKEAPF----VFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIEN

1vioA

0.32

0.28

0.89

4.90

MUSTER

------------SLRLDKFIAENVGLTRSQATKAIRQSAVKINGEIVKSGSVQISQE-DEIYFEDELLTWIEEGQYFMLNKPQGCVCSNDD---YPTIYQFFDYPL--AGKLHSAGRLDVDTTGLVLLTDDGQWSHRITSPKHHCEKTYLVTLADPVEENYSAACAEGILLEKEPTKPAKLEILDDY----NVNLTISEGRYHQVKRMFAALGNKVVGLHRWKIGDVVLDSLEEGEYRPLTQSEIEKLV-----

1vioA

0.32

0.28

0.89

9.91

dPPAS

------------SLRLDKFIAENVGLTRSQATKAIRQSAVKINGEIVKSGSVQISQE-DEIYFEDELLTWIEEGQYFMLNKPQGCVCSNDD---YPTIYQFFDYPLA--GKLHSAGRLDVDTTGLVLLTDDGQWSHRITSPKHHCEKTYLVTLADPVEENYSAACAEGILLEKEPTKPAKLEILDDY----NVNLTISEGRYHQVKRMFAALGNKVVGLHRWKIGDVVLDSLEEGEYRPLTQSEIEKLV-----

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=1.45

Estimated TM-score = 0.92±0.06

Estimated RMSD = 3.0±2.1Å

Download Model 2

C-score=-1.06

Download Model 3

C-score=-1.10

Download Model 4

C-score=0.56

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3dh3B	0.899	1.05	0.342	0.921
2	1vioA	0.672	3.24	0.314	0.787
3	4labA	0.628	2.46	0.387	0.713
4	1kslA	0.621	3.19	0.261	0.717
5	2omlA	0.597	2.14	0.335	0.653
6	3u28A	0.571	3.37	0.157	0.681
7	2apoA	0.566	3.27	0.152	0.673
8	1k8wA	0.562	3.10	0.148	0.665
9	1ze1A	0.560	2.92	0.169	0.653
10	2v9kA	0.557	3.81	0.091	0.701

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.55	12	1ksvA	U	Rep, Mult	117,118,119,122,149,197,203,204,205,206,219
2	0.22	4	3dh3A	NUC	Rep, Mult	15,17,18,27,28,29,32,49,51,86,89,90,111,113,116,117,119,120,122,132,135,136,139,140,149,200,203,204,205,206,219,221
3	0.19	9	3lwoA	NUC	Rep, Mult	88,114,115,116,117,119,120,149,174,176,200,204,205,206,219,221
4	0.02	1	3mm6D	SF4	Rep, Mult	177,200,201,203,204,206,207,208
5	0.02	1	4nz6A	DLY	Rep, Mult	117,118,119,122,149,219
6	0.02	1	3lwrA	RQA	Rep, Mult	88,117,119

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.162	1ze2B	0.424	2.95	0.205	0.500	4.2.1.70	119,149
2	0.141	1k8wA	0.562	3.10	0.148	0.665	4.2.1.70	119,149
3	0.107	1s71B	0.524	3.96	0.231	0.669	4.2.1.70	119,149
4	0.060	3gipA	0.394	5.69	0.035	0.665	3.5.1.82	22
5	0.060	2gv9B	0.422	5.40	0.111	0.665	2.7.7.7	NA
6	0.060	2v4jD	0.430	6.06	0.032	0.736	1.8.99.3	81
7	0.060	3mtjA	0.418	5.64	0.093	0.677	1.1.1.3	20,38
8	0.060	1chmA	0.424	5.46	0.055	0.677	3.5.3.3	25,27,34
9	0.060	1rm6A	0.401	6.32	0.037	0.713	1.3.99.20	NA
10	0.060	3gh4A	0.395	6.34	0.083	0.717	3.2.1.52	NA
11	0.060	4kbpA	0.398	5.83	0.030	0.661	3.1.3.2	NA
12	0.060	3fwmA	0.404	5.84	0.042	0.689	2.4.1.129,	NA
13	0.060	1js4A	0.407	5.21	0.062	0.618	3.2.1.4	NA
14	0.060	3c20B	0.369	6.15	0.067	0.650	2.7.2.4	110,112
15	0.060	1k1dA	0.387	5.44	0.060	0.618	3.5.2.-	185
16	0.060	1yifA	0.411	5.60	0.038	0.673	3.2.1.37	NA
17	0.060	3fwlA	0.412	5.44	0.036	0.661	2.4.1.129	NA
18	0.060	3l24A	0.396	5.95	0.048	0.677	3.1.8.2,3.4.13.9,3.1.8.1	250
19	0.060	3c7bE	0.420	5.86	0.072	0.705	1.8.99.3	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.54	0.863	1.99	0.40	0.94	4lgtA	GO:0000455 GO:0001522 GO:0003723 GO:0005829 GO:0006364 GO:0009451 GO:0009982 GO:0016853 GO:0016866
1	0.44	0.899	1.05	0.34	0.92	3dh3B	GO:0000455 GO:0001522 GO:0003723 GO:0005829 GO:0006364 GO:0009451 GO:0009982 GO:0016853 GO:0016866
2	0.41	0.642	3.04	0.26	0.74	1kskA	GO:0000455 GO:0001522 GO:0003723 GO:0005829 GO:0006364 GO:0009451 GO:0009982 GO:0016853 GO:0016866
3	0.34	0.672	3.24	0.31	0.79	1vioA	GO:0000455 GO:0001522 GO:0003723 GO:0005829 GO:0006364 GO:0009451 GO:0009982 GO:0016853 GO:0016866
4	0.32	0.597	2.14	0.34	0.65	2omlA	GO:0000455 GO:0001522 GO:0003723 GO:0005829 GO:0006364 GO:0009451 GO:0009982 GO:0016853 GO:0016866
5	0.06	0.310	6.28	0.06	0.53	3wv6A	GO:0002376 GO:0002519 GO:0004871 GO:0005534 GO:0005576 GO:0005615 GO:0005622 GO:0005634 GO:0005737 GO:0006935 GO:0006954 GO:0007565 GO:0010628 GO:0010629 GO:0019899 GO:0030246 GO:0032496 GO:0032673 GO:0032674 GO:0032682 GO:0032689 GO:0032720 GO:0032753 GO:0032834 GO:0034134 GO:0034142 GO:0038066 GO:0042346 GO:0043123 GO:0043305 GO:0045953 GO:0046007 GO:0046598 GO:0048030 GO:0050718 GO:0051092 GO:0060135 GO:0070062 GO:0070241 GO:0070371 GO:0070374 GO:0070555 GO:0071346 GO:0071636 GO:0071639 GO:0097029 GO:0098586 GO:1900744 GO:1902715 GO:1904469 GO:2000484 GO:2000510 GO:2000562 GO:2000563 GO:2000667 GO:2000670 GO:2000778 GO:2001181 GO:2001184 GO:2001190 GO:2001200 GO:2001269
6	0.06	0.282	6.31	0.04	0.50	3ppsA	GO:0005507 GO:0016491 GO:0046872 GO:0052716 GO:0055114
7	0.06	0.367	6.38	0.05	0.65	3i01A	GO:0003824 GO:0006091 GO:0015977 GO:0016151 GO:0016491 GO:0018492 GO:0043885 GO:0046872 GO:0051536 GO:0051539 GO:0055114
8	0.06	0.269	5.66	0.05	0.44	3j9wAD	GO:0003723 GO:0003735 GO:0005622 GO:0005840 GO:0006412 GO:0015935 GO:0019843 GO:0030529 GO:0045903
9	0.06	0.314	6.29	0.04	0.55	2blfA	GO:0016491 GO:0030151 GO:0042128 GO:0055114
10	0.06	0.238	4.51	0.14	0.31	4a2iD	GO:0000900 GO:0003723 GO:0003735 GO:0005622 GO:0005829 GO:0005840 GO:0006351 GO:0006353 GO:0006355 GO:0006412 GO:0006417 GO:0015935 GO:0019843 GO:0022627 GO:0030529 GO:0031564 GO:0045903 GO:0045947 GO:0046677 GO:0048027 GO:1990145
11	0.06	0.331	6.26	0.03	0.58	4fn5A	GO:0000166 GO:0003746 GO:0003924 GO:0005525 GO:0005622 GO:0005737 GO:0006412 GO:0006414
12	0.06	0.259	6.11	0.05	0.45	4givA	GO:0000070 GO:0000413 GO:0000794 GO:0003755 GO:0005634 GO:0005940 GO:0006457 GO:0016853 GO:0016925 GO:0031386 GO:0042802 GO:0046872
13	0.06	0.268	6.29	0.04	0.48	3v7oB	GO:0003723 GO:0006351 GO:0019012 GO:0019013 GO:0030430 GO:0046872
14	0.06	0.245	4.40	0.17	0.35	4aqyD	GO:0003723 GO:0003735 GO:0005622 GO:0005840 GO:0006412 GO:0015935 GO:0019843 GO:0030529 GO:0046872
15	0.06	0.236	5.28	0.04	0.37	3ktsA	GO:0003723 GO:0006071 GO:0006351 GO:0006355 GO:0009607
16	0.06	0.202	3.08	0.15	0.24	2k6pA	GO:0003723
17	0.06	0.208	4.80	0.08	0.30	4y0bA	GO:0009507 GO:0009532 GO:0009536 GO:0009570 GO:0009579 GO:0009941 GO:0019538
18	0.06	0.227	4.80	0.10	0.33	3jteA	GO:0000160 GO:0003824 GO:0005622

Consensus prediction of GO terms

Molecular Function	GO:0009982	GO:0003723
GO-Score	0.93	0.93
Biological Processes	GO:0000455
GO-Score	0.93
Cellular Component	GO:0005829
GO-Score	0.93

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.