I-TASSER results

Input Sequence in FASTA format

>protein (250 residues)
MVDDRQGRRGGRRPRSAAADNRPAFRDGPAIPPGIHARQLAPEIRRELSTLDRATADAVA
CHLVAAGELIDDDPEAALRHARAARVRASRIAAVREAVGIAAYRCGDWAQALAELRAARR
MGSKSPLLALIADCERGLGRPQRAIELARGSEAVELSGDAADELRIVAAGARADLGQLEQ
ALTVLSTPQLDPGRTGSTAARLFYAYAEILLALGRGDEALQWFLRSAAADIDGVTDAEDR
VDELGAREQK

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MVDDRQGRRGGRRPRSAAADNRPAFRDGPAIPPGIHARQLAPEIRRELSTLDRATADAVACHLVAAGELIDDDPEAALRHARAARVRASRIAAVREAVGIAAYRCGDWAQALAELRAARRMGSKSPLLALIADCERGLGRPQRAIELARGSEAVELSGDAADELRIVAAGARADLGQLEQALTVLSTPQLDPGRTGSTAARLFYAYAEILLALGRGDEALQWFLRSAAADIDGVTDAEDRVDELGAREQK
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
Conf.Score	9988888888777778776666666678899988898788999999998688778999999999999998759999999999999988986899999999999989999999999999985999678899999888779989999999855654899788999999999999988999999999998754678888645899999999999989999999999999985866567899999997666789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MVDDRQGRRGGRRPRSAAADNRPAFRDGPAIPPGIHARQLAPEIRRELSTLDRATADAVACHLVAAGELIDDDPEAALRHARAARVRASRIAAVREAVGIAAYRCGDWAQALAELRAARRMGSKSPLLALIADCERGLGRPQRAIELARGSEAVELSGDAADELRIVAAGARADLGQLEQALTVLSTPQLDPGRTGSTAARLFYAYAEILLALGRGDEALQWFLRSAAADIDGVTDAEDRVDELGAREQK
Prediction	7345467557545666455664564574161376143740356026404614572053002000000312362153025004202741540120010001001314516400520330241244431000000002224326301410555545615462210010000002322642640152045353557464522110120003004614447303500540371347623304301540466578
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
MVDDRQGRRGGRRPRSAAADNRPAFRDGPAIPPGIHARQLAPEIRRELSTLDRATADAVACHLVAAGELIDDDPEAALRHARAARVRASRIAAVREAVGIAAYRCGDWAQALAELRAARRMGSKSPLLALIADCERGLGRPQRAIELARGSEAVELSGDAADELRIVAAGARADLGQLEQALTVLSTPQLDPGRTGSTAARLFYAYAEILLALGRGDEALQWFLRSAAADIDGVTDAEDRVDELGAREQK

2q7fA

0.16

0.12

0.77

1.74

MUSTER

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMNGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDH----MLALHAKKL----

2q7fA

0.16

0.12

0.77

1.76

dPPAS

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMEGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKL--------

2q7fA

0.16

0.12

0.77

2.53

wdPPAS

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMEGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKL--------

2q7fA

0.16

0.12

0.77

2.52

wMUSTER

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMEGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKL--------

2q7fA

0.16

0.12

0.77

2.51

wPPAS

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMEGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDH----MLALHAKKL----

4xi0A

0.12

0.08

0.70

2.93

dPPAS2

-----------------------------------------------------AMGDKAKLYRNISQRCLRRSPEEALRYLKEWARHEKNDPEPLYQMGIALANLGDYQRAVTVFDKVLKLRPNFMASYRKGAVLLKIKQYKLALPVLEAVVAAAPAD---ARAYYLLGLAYDGDEQLEKGIEAMQKAV----DLDPEEIKYHQHLGFMNVRKDDHKTAAEHFTKVMELERSQDS---------------

2q7fA

0.16

0.12

0.77

1.94

PPAS

------------------------------------------AAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMEGDLFYMLGTVLVKLEQPKLALPYLQRAVELNEND---TEARFQFGMCLANEGMLDEALSQFAAVT----EQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDH----MLALHAKKL----

4xi0A

0.12

0.08

0.70

3.16

Env-PPAS

-----------------------------------------------------AMGDKAKLYRNISQRCLRRSPEEALRYLKEWARHEKNDPEPLYQMGIALANLGDYQRAVTVFDKVLKLRPNFMASYRKGAVLLKIKQYKLALPVLEAVVAAAPAD---ARAYYLLGLAYDGDEQLEKGIEAMQKAV----DLDPEEIKYHQHLGFMNVRKDDHKTAAEHFTKVMELERSQDS---------------

4ui9J4

0.08

0.07

0.87

1.66

MUSTER

--------KYNKPSETVIPESVNGLEKNLDV---YYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHNEHARRYLSKATTLEKTGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGC---HLPMLYIGLEYGLTNNSKLAERFFSQAL----SIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKA-IGN--------------

3vtxA

0.11

0.08

0.72

1.74

dPPAS

--------------------------------------------------------TTTIYMDIGDKKRTKGDFDGAIRAYKKVLKADPNNVETLLKLGKTYMDIGLPNDAIESLKKFVVLDTTAEAYYILGSANFMIDEKQAAIDALQRAIALNTVY---ADAYYKLGLVYDSMGEHDKAIEAYEKTI----SIKPGFIRAYQSIGLAYEGKGLRDEAVKYFKKALEKEEKK---AKYELALVPR----

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.02

Estimated TM-score = 0.59±0.14

Estimated RMSD = 8.0±4.4Å

Download Model 2

C-score=-1.17

Download Model 3

C-score=-1.53

Download Model 4

C-score=-4.07

Download Model 5

C-score=-4.52

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2q7fA	0.736	1.44	0.155	0.772
2	4a1sA	0.681	3.86	0.098	0.864
3	1w3bA	0.671	3.15	0.086	0.820
4	4bujB	0.667	3.10	0.100	0.808
5	3sf4A	0.666	3.53	0.100	0.844
6	4g1tA	0.660	3.42	0.118	0.820
7	4abnA	0.656	4.09	0.113	0.868
8	3q15A	0.650	4.11	0.070	0.872
9	2pziA	0.641	4.42	0.091	0.888
10	2fi7A	0.638	3.36	0.129	0.804

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.18	7	3ro3A	III	Rep, Mult	133,136,137,162,163,167,170,173,174,201,204,205,208,211,212,239,242,245
2	0.13	5	2qfcB	III	Rep, Mult	129,133,134,136,137,163,166,167,170,198,201,204
3	0.05	2	4am9A	III	Rep, Mult	62,66,69,74,81,93,96,97,100,103,130,163
4	0.03	1	1fchA	III	Rep, Mult	142,143,145,146,177,179
5	0.03	1	1fchA	III	Rep, Mult	179,180,182,183,215,218
6	0.03	1	1na0B	IPT	Rep, Mult	69,100,103,104,130
7	0.03	1	3fp4A	III	Rep, Mult	62,66,69,81,93,97,130
8	0.03	1	2vq2A	SO3	Rep, Mult	177,179,180

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.090	1w3bA	0.671	3.15	0.086	0.820	2.4.1.-	NA
2	0.060	2qnoA	0.525	4.92	0.057	0.780	3.2.1.4	142
3	0.060	1fmiA	0.502	5.17	0.054	0.780	3.2.1.113	NA
4	0.060	1f1sA	0.518	4.89	0.049	0.792	4.2.2.1	NA
5	0.060	5acnA	0.483	5.86	0.060	0.824	4.2.1.3	NA
6	0.060	1hn0A	0.518	5.27	0.083	0.808	4.2.2.20	172
7	0.060	3ebgA	0.527	5.52	0.086	0.848	3.4.11.-	NA
8	0.060	2vn4A	0.504	5.25	0.069	0.796	3.2.1.3	208
9	0.060	1kktA	0.504	4.85	0.053	0.744	3.2.1.113	NA
10	0.060	1w3bB	0.667	3.41	0.120	0.820	2.4.1.-	92
11	0.060	1h19A	0.478	4.45	0.060	0.684	3.3.2.6	NA
12	0.060	1ks8A	0.489	4.67	0.069	0.700	3.2.1.4	NA
13	0.060	1rw9A	0.507	5.56	0.061	0.828	4.2.2.5	172
14	0.060	1w6jA	0.490	4.95	0.097	0.744	5.4.99.7	NA
15	0.060	2f6dA	0.511	4.76	0.043	0.740	3.2.1.3	NA
16	0.060	3c5wA	0.467	4.79	0.088	0.704	3.1.3.16	135
17	0.060	2c0lA	0.578	4.12	0.112	0.756	2.3.1.176	173
18	0.060	1i8qA	0.531	4.69	0.045	0.784	4.2.2.1	96
19	0.060	1ia7A	0.492	5.24	0.056	0.752	3.2.1.4	NA
20	0.060	2pziA	0.641	4.42	0.091	0.888	2.7.11.1	135

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.30	0.736	1.44	0.15	0.77	2q7fA
1	0.25	0.667	3.41	0.12	0.82	1w3bB	GO:0000123 GO:0000791 GO:0001933 GO:0001934 GO:0005547 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005886 GO:0006041 GO:0006110 GO:0006486 GO:0006493 GO:0006915 GO:0007165 GO:0007584 GO:0008047 GO:0008134 GO:0008289 GO:0008375 GO:0010628 GO:0010801 GO:0016020 GO:0016262 GO:0016568 GO:0016740 GO:0016757 GO:0019904 GO:0030854 GO:0030900 GO:0031397 GO:0032868 GO:0032869 GO:0032922 GO:0033137 GO:0035020 GO:0042277 GO:0042588 GO:0043005 GO:0043025 GO:0043085 GO:0043981 GO:0043982 GO:0043984 GO:0043995 GO:0043996 GO:0045793 GO:0045862 GO:0045944 GO:0046626 GO:0046972 GO:0048015 GO:0048029 GO:0048312 GO:0048511 GO:0051571 GO:0060548 GO:0061087 GO:0070207 GO:0070208 GO:0070688 GO:0071222 GO:0071300 GO:0071333 GO:0080182 GO:0090315 GO:0090526 GO:0097237 GO:0097363 GO:1900038 GO:1900182 GO:1903428
2	0.23	0.671	3.15	0.09	0.82	1w3bA	GO:0000123 GO:0000791 GO:0001933 GO:0001934 GO:0005547 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005886 GO:0006041 GO:0006110 GO:0006486 GO:0006493 GO:0006915 GO:0007165 GO:0007584 GO:0008047 GO:0008134 GO:0008289 GO:0008375 GO:0010628 GO:0010801 GO:0016020 GO:0016262 GO:0016568 GO:0016740 GO:0016757 GO:0019904 GO:0030854 GO:0030900 GO:0031397 GO:0032868 GO:0032869 GO:0032922 GO:0033137 GO:0035020 GO:0042277 GO:0042588 GO:0043005 GO:0043025 GO:0043085 GO:0043981 GO:0043982 GO:0043984 GO:0043995 GO:0043996 GO:0045793 GO:0045862 GO:0045944 GO:0046626 GO:0046972 GO:0048015 GO:0048029 GO:0048312 GO:0048511 GO:0051571 GO:0060548 GO:0061087 GO:0070207 GO:0070208 GO:0070688 GO:0071222 GO:0071300 GO:0071333 GO:0080182 GO:0090315 GO:0090526 GO:0097237 GO:0097363 GO:1900038 GO:1900182 GO:1903428
3	0.20	0.667	3.10	0.10	0.81	4bujB	GO:0005634 GO:0005737 GO:0034427 GO:0051607 GO:0055087 GO:0070478 GO:0070481
4	0.20	0.678	3.88	0.10	0.86	4a1sA	GO:0000132 GO:0005938 GO:0007400 GO:0007405 GO:0008105 GO:0008356 GO:0019904 GO:0030695 GO:0040001 GO:0045167 GO:0045175 GO:0045177 GO:0045179 GO:0045185 GO:0050790 GO:0051294 GO:0055059
5	0.19	0.525	3.30	0.16	0.64	2pl2A
6	0.18	0.543	4.69	0.10	0.74	5aioA	GO:0000127 GO:0000999 GO:0001002 GO:0001003 GO:0001005 GO:0001008 GO:0001009 GO:0001021 GO:0001041 GO:0003677 GO:0005634 GO:0005654 GO:0006351 GO:0006355 GO:0006383 GO:0006385 GO:0008301 GO:0042791
7	0.17	0.578	4.17	0.11	0.75	2c0mC	GO:0000268 GO:0005052 GO:0005622 GO:0005737 GO:0005777 GO:0005778 GO:0005782 GO:0005829 GO:0006625 GO:0006810 GO:0008022 GO:0015031 GO:0016020 GO:0016558 GO:0016560 GO:0016561 GO:0019899 GO:0031267 GO:0043234 GO:0045046 GO:0047485 GO:0051262 GO:1901094
8	0.17	0.558	4.32	0.14	0.76	5a31Y	GO:0005634 GO:0005654 GO:0005680 GO:0005829 GO:0007049 GO:0007067 GO:0016567 GO:0019903 GO:0031145 GO:0042787 GO:0043161 GO:0051301 GO:0051436 GO:0051437 GO:0051439 GO:0070979
9	0.17	0.572	3.98	0.07	0.76	3lcaA	GO:0005739 GO:0005741 GO:0006626 GO:0015266 GO:0016020 GO:0016021 GO:0031307 GO:0071806
10	0.17	0.638	3.36	0.13	0.80	2fi7A	GO:0009297 GO:0043683 GO:0046903
11	0.16	0.628	3.67	0.13	0.80	5dseA	GO:0005737 GO:0005829 GO:0005886 GO:0016020 GO:0046854 GO:0090002
12	0.16	0.684	3.92	0.09	0.87	5a6cB	GO:0000132 GO:0000166 GO:0000922 GO:0001965 GO:0005092 GO:0005654 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005938 GO:0007052 GO:0007155 GO:0007165 GO:0007186 GO:0007267 GO:0008022 GO:0017016 GO:0030054 GO:0030695 GO:0034332 GO:0042802 GO:0043547 GO:0045177 GO:0050790 GO:0051661 GO:0060487 GO:0090557 GO:0097431 GO:0098609 GO:0098641
13	0.16	0.601	3.05	0.12	0.72	4jhrA	GO:0000132 GO:0000166 GO:0000922 GO:0001965 GO:0005092 GO:0005737 GO:0005856 GO:0005938 GO:0007052 GO:0030695 GO:0042802 GO:0045177 GO:0050790 GO:0051661 GO:0060487 GO:0097431
14	0.16	0.630	4.11	0.12	0.82	4horA	GO:0000049 GO:0002376 GO:0003723 GO:0003727 GO:0005886 GO:0015629 GO:0016020 GO:0032587 GO:0042995 GO:0043231 GO:0044822 GO:0045087 GO:0045177 GO:0051607
15	0.16	0.572	4.68	0.07	0.83	3fp3A	GO:0005739 GO:0005741 GO:0006626 GO:0015266 GO:0016020 GO:0016021 GO:0031307 GO:0071806
16	0.14	0.573	4.02	0.12	0.74	4eqfA	GO:0000268 GO:0005052 GO:0005737 GO:0005778 GO:0005829 GO:0016020 GO:0016560 GO:0030425 GO:0031267 GO:0042391 GO:0043235 GO:0043949 GO:0045185
17	0.12	0.574	3.95	0.10	0.74	1xnfB	GO:0005886 GO:0007049 GO:0016020 GO:0030674 GO:0051301
18	0.12	0.590	4.52	0.11	0.80	4xifA	GO:0000123 GO:0000791 GO:0001933 GO:0001934 GO:0005547 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005886 GO:0006041 GO:0006110 GO:0006486 GO:0006493 GO:0006915 GO:0007165 GO:0007584 GO:0008047 GO:0008134 GO:0008289 GO:0008375 GO:0010628 GO:0010801 GO:0016020 GO:0016262 GO:0016568 GO:0016740 GO:0016757 GO:0019904 GO:0030854 GO:0030900 GO:0031397 GO:0032868 GO:0032869 GO:0032922 GO:0033137 GO:0035020 GO:0042277 GO:0042588 GO:0043005 GO:0043025 GO:0043085 GO:0043981 GO:0043982 GO:0043984 GO:0043995 GO:0043996 GO:0045793 GO:0045862 GO:0045944 GO:0046626 GO:0046972 GO:0048015 GO:0048029 GO:0048312 GO:0048511 GO:0051571 GO:0060548 GO:0061087 GO:0070207 GO:0070208 GO:0070688 GO:0071222 GO:0071300 GO:0071333 GO:0080182 GO:0090315 GO:0090526 GO:0097237 GO:0097363 GO:1900038 GO:1900182 GO:1903428
19	0.10	0.591	4.15	0.08	0.80	2gw1A	GO:0005739 GO:0005741 GO:0005742 GO:0006626 GO:0006886 GO:0015266 GO:0015450 GO:0016020 GO:0016021 GO:0030150 GO:0030943 GO:0031307 GO:0045039
20	0.09	0.487	2.05	0.17	0.54	2fo7A
21	0.07	0.554	3.91	0.12	0.72	5a01A	GO:0006486 GO:0006493 GO:0008375 GO:0016740 GO:0016757 GO:0035220 GO:0045475

Consensus prediction of GO terms

Molecular Function	GO:0019904	GO:0097363	GO:0043996	GO:0043995	GO:0048029	GO:0016262	GO:0005547	GO:0042277	GO:0046972	GO:0008134	GO:0008047	GO:0060589
GO-Score	0.54	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.40
Biological Processes	GO:0045944	GO:0035020	GO:0006493	GO:0007584	GO:0048015	GO:0046626	GO:0071333	GO:0006110	GO:0090526	GO:0030900	GO:1900038	GO:0071300	GO:0070207	GO:1903428	GO:1900182	GO:0043981	GO:0071222	GO:0090315	GO:0006041	GO:0070208	GO:0045793	GO:0043984	GO:0031397	GO:0097237	GO:0001934	GO:0060548	GO:0080182	GO:0006915	GO:0048312	GO:0030854	GO:0016568	GO:0045862	GO:0043085	GO:0061087	GO:0033137	GO:0051571	GO:0010801	GO:0043982	GO:0032922	GO:0002252	GO:0098542	GO:0098722	GO:0048867	GO:0051235	GO:1903047	GO:0043928	GO:0030010	GO:0000184	GO:0051293	GO:0055057	GO:0008105	GO:0009615	GO:0014017
GO-Score	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40	0.40
Cellular Component	GO:0070688	GO:0005829	GO:0000123	GO:0000791	GO:0043025	GO:0005886	GO:0043005	GO:0005739	GO:0042588	GO:0099738	GO:0045177
GO-Score	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.42	0.40	0.40

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv1691

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]