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I-TASSER results for job id Rv1671

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)


 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)


  Ligand binding sites

Rank C-score Cluster
size
PDB
Hit
Lig
Name
Download
Complex
Ligand Binding Site Residues
10.08 4 4uxzC 79M Rep, Mult 118,121,122,125
20.06 3 1c6gA KR Rep, Mult 80,83,84,107
30.06 3 1c61A KR Rep, Mult 73,76,77,79,114,117,118
40.06 3 4o6nB MPG Rep, Mult 28,105,109
50.06 3 2dysN DCW Rep, Mult 40,82
60.06 3 2ih1C 1EM Rep, Mult 95,104,108
70.02 1 2wse1 CLA Rep, Mult 46,49
80.02 1 2vt4B SOG Rep, Mult 26,29,30
90.02 1 3j0eG NUC Rep, Mult 99,102
100.02 1 2jk5C L2C Rep, Mult 95,104
110.02 1 3ak1B EDO Rep, Mult 47,71
120.02 1 3kdpC CLR Rep, Mult 32,36

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit
TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.0601vdkA0.6153.640.0480.9154.2.1.29
20.0601w27A0.5794.120.0820.9004.3.1.24NA
30.0601j3uA0.6313.250.0330.8854.3.1.1NA
40.0602o6yA0.5704.030.0410.8774.3.1.-71
50.0601i0aA0.5933.680.1150.8774.3.2.1NA
60.0603d4sA0.6153.840.0390.9623.2.1.1783,109
70.0601qleA0.5884.350.0620.9391.9.3.1NA
80.0602pfmA0.5623.950.0500.8774.3.2.2NA
90.0601m56A0.6034.520.1010.9541.9.3.1102
100.0601k62B0.6033.460.0160.8624.3.2.1NA
110.0601dcnB0.5843.820.0580.8854.3.2.1NA
120.0601xmeA0.5964.260.1030.9311.9.3.1NA
130.0601f1oA0.5614.050.0660.9234.3.2.2NA
140.0601yfmA0.5933.630.0240.9004.2.1.2NA
150.0601y5nC0.5243.780.1060.8001.7.99.468
160.0601fftA0.5734.420.0630.9391.10.3.-NA
170.0602fenD0.5654.110.0480.9005.5.1.2NA
180.0601tj7A0.5883.570.0310.8694.3.2.1NA
190.0602occN0.6054.400.0930.9461.9.3.1117

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.160.6003.650.090.882ydvA GO:0001609 GO:0001973 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006171 GO:0006909 GO:0006915 GO:0006954 GO:0006968 GO:0007165 GO:0007186 GO:0007188 GO:0007267 GO:0007417 GO:0007596 GO:0007600 GO:0008015 GO:0010579 GO:0016020 GO:0016021 GO:0019899 GO:0042802 GO:0044267
10.070.6023.870.060.924n6hA GO:0000060 GO:0004871 GO:0004930 GO:0004985 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007186 GO:0007187 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0008344 GO:0009055 GO:0010629 GO:0016020 GO:0016021 GO:0019233 GO:0020037 GO:0022900 GO:0031226 GO:0031982 GO:0032460 GO:0032590 GO:0032793 GO:0033138 GO:0038003 GO:0038046 GO:0042597 GO:0042755 GO:0042923 GO:0043005 GO:0043679 GO:0045121 GO:0045211 GO:0046872 GO:0051881 GO:0051924 GO:0051930 GO:0055114 GO:0071363 GO:0071456 GO:0097237
20.070.5674.430.070.934djhB GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004985 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007186 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0007600 GO:0007610 GO:0007626 GO:0008152 GO:0009253 GO:0009314 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019233 GO:0019835 GO:0030425 GO:0030430 GO:0031635 GO:0032868 GO:0033603 GO:0033685 GO:0038003 GO:0038048 GO:0040017 GO:0042220 GO:0042711 GO:0042742 GO:0042755 GO:0042923 GO:0043005 GO:0043025 GO:0043204 GO:0043278 GO:0043627 GO:0043679 GO:0044849 GO:0045202 GO:0045471 GO:0046877 GO:0048148 GO:0050951 GO:0051607 GO:0051930 GO:0071222 GO:1900745 GO:1901381 GO:1903715 GO:1903937 GO:1990708 GO:2000505
30.070.5644.260.070.923rzeA GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004969 GO:0005654 GO:0005737 GO:0005886 GO:0005887 GO:0006954 GO:0007165 GO:0007186 GO:0007200 GO:0007613 GO:0008152 GO:0008542 GO:0009253 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019229 GO:0019835 GO:0030430 GO:0032962 GO:0042742 GO:0043114 GO:0045907 GO:0048016 GO:0048167 GO:0048245 GO:0050804 GO:0071420
40.070.5934.680.070.984s0vA GO:0004373 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007200 GO:0007218 GO:0007268 GO:0007631 GO:0008188 GO:0010840 GO:0016020 GO:0016021 GO:0016499 GO:0017046 GO:0022410 GO:0032870 GO:0042277 GO:0045187 GO:0051480 GO:1901652
50.070.5564.200.070.922lnlA GO:0002407 GO:0004871 GO:0004918 GO:0004930 GO:0004950 GO:0005886 GO:0006935 GO:0006954 GO:0007165 GO:0007166 GO:0007186 GO:0016020 GO:0016021 GO:0016494 GO:0019959 GO:0031623 GO:0038112 GO:0070098
60.070.5774.160.030.924u15B GO:0003056 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006939 GO:0007165 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007586 GO:0008144 GO:0008152 GO:0009253 GO:0016020 GO:0016021 GO:0016323 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019229 GO:0019835 GO:0030054 GO:0030425 GO:0032279 GO:0042166 GO:0042742 GO:0043679 GO:0045202 GO:0045211 GO:0045987 GO:0046541
70.070.5904.030.050.924u14A GO:0003056 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006939 GO:0007165 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007586 GO:0008144 GO:0008152 GO:0009253 GO:0016020 GO:0016021 GO:0016323 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019229 GO:0019835 GO:0030054 GO:0030425 GO:0030430 GO:0032279 GO:0042166 GO:0042742 GO:0043679 GO:0045202 GO:0045211 GO:0045987 GO:0046541
80.070.5594.520.090.954ldeA GO:0001666 GO:0001889 GO:0001965 GO:0001993 GO:0002024 GO:0002025 GO:0002028 GO:0002032 GO:0002086 GO:0003059 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004935 GO:0004941 GO:0005634 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005886 GO:0005887 GO:0005901 GO:0006898 GO:0006940 GO:0007165 GO:0007166 GO:0007171 GO:0007186 GO:0007188 GO:0007189 GO:0007190 GO:0007267 GO:0007565 GO:0007568 GO:0008144 GO:0008152 GO:0008179 GO:0008284 GO:0008306 GO:0008333 GO:0009253 GO:0009409 GO:0010765 GO:0015459 GO:0016020 GO:0016021 GO:0016324 GO:0016525 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0019899 GO:0030279 GO:0030424 GO:0030425 GO:0030430 GO:0030501 GO:0031398 GO:0031649 GO:0031713 GO:0032403 GO:0032570 GO:0032781 GO:0032809 GO:0033574 GO:0035240 GO:0035249 GO:0035255 GO:0035811 GO:0040015 GO:0042060 GO:0042312 GO:0042383 GO:0042742 GO:0042803 GO:0043065 GO:0043197 GO:0043231 GO:0043235 GO:0043268 GO:0043410 GO:0043627 GO:0044849 GO:0045453 GO:0045823 GO:0045909 GO:0045944 GO:0045986 GO:0048633 GO:0050728 GO:0050873 GO:0051379 GO:0051380 GO:0051924 GO:0051930 GO:0060079 GO:0071456 GO:0071548 GO:0071867 GO:0071880 GO:0090331 GO:0097421 GO:1901098 GO:1904504 GO:1904925
90.070.5884.200.060.955c1mA GO:0001965 GO:0002438 GO:0004871 GO:0004930 GO:0004979 GO:0004985 GO:0005245 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0005925 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007194 GO:0007200 GO:0007204 GO:0007218 GO:0007268 GO:0007626 GO:0008022 GO:0009314 GO:0016020 GO:0016021 GO:0019233 GO:0019904 GO:0030425 GO:0030818 GO:0031005 GO:0031635 GO:0031681 GO:0032094 GO:0032100 GO:0032496 GO:0032590 GO:0032839 GO:0033554 GO:0038003 GO:0038047 GO:0042060 GO:0042220 GO:0042383 GO:0042755 GO:0042923 GO:0043005 GO:0043204 GO:0043278 GO:0043950 GO:0043951 GO:0044849 GO:0045019 GO:0045121 GO:0045429 GO:0045471 GO:0048149 GO:0050769 GO:0051481 GO:0051930 GO:0060079 GO:0061358 GO:0070374 GO:0070588 GO:0070848 GO:0071315 GO:0098794 GO:2000310
100.070.5963.750.050.903vw7A GO:0000186 GO:0001965 GO:0002248 GO:0003105 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005102 GO:0005576 GO:0005769 GO:0005770 GO:0005794 GO:0005829 GO:0005886 GO:0005887 GO:0005901 GO:0006919 GO:0006954 GO:0007165 GO:0007186 GO:0007200 GO:0007204 GO:0007205 GO:0007260 GO:0007262 GO:0007529 GO:0007596 GO:0007599 GO:0008152 GO:0008284 GO:0008285 GO:0009253 GO:0009611 GO:0009653 GO:0009986 GO:0014068 GO:0015057 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030168 GO:0030193 GO:0030194 GO:0030335 GO:0030430 GO:0031094 GO:0031594 GO:0031681 GO:0032496 GO:0032651 GO:0032967 GO:0035025 GO:0042742 GO:0043123 GO:0043280 GO:0043410 GO:0043524 GO:0045211 GO:0045893 GO:0045907 GO:0045987 GO:0046427 GO:0048873 GO:0051209 GO:0051281 GO:0051482 GO:0051928 GO:0051930 GO:0060155 GO:0070374 GO:0070493 GO:1900134 GO:2000484 GO:2000778
110.070.6103.800.080.934xnwC GO:0001934 GO:0001973 GO:0004871 GO:0004872 GO:0004930 GO:0005506 GO:0005524 GO:0005739 GO:0005829 GO:0005886 GO:0005887 GO:0007165 GO:0007166 GO:0007186 GO:0007193 GO:0007200 GO:0007204 GO:0007568 GO:0007596 GO:0007599 GO:0008347 GO:0009055 GO:0009612 GO:0009986 GO:0010469 GO:0010700 GO:0016020 GO:0016021 GO:0016323 GO:0016324 GO:0019233 GO:0023019 GO:0030168 GO:0030425 GO:0031686 GO:0032962 GO:0035589 GO:0042060 GO:0042312 GO:0042755 GO:0043270 GO:0043531 GO:0044297 GO:0045028 GO:0045031 GO:0045032 GO:0045211 GO:0045944 GO:0046872 GO:0046887 GO:0046982 GO:0051100 GO:0055114 GO:0060406 GO:0070374 GO:0070848 GO:0071407 GO:0072659 GO:0090075 GO:0097110 GO:0097481
120.070.5944.120.090.924zj8A GO:0004373 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007268 GO:0007631 GO:0008188 GO:0016020 GO:0016021 GO:0016499 GO:0017046 GO:0032870 GO:0042277 GO:0045187 GO:0051480 GO:1901652
130.070.5614.200.060.893kj6A GO:0001666 GO:0001889 GO:0001965 GO:0001993 GO:0002024 GO:0002025 GO:0002028 GO:0002032 GO:0002086 GO:0003059 GO:0004871 GO:0004930 GO:0004935 GO:0004941 GO:0005634 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005886 GO:0005887 GO:0005901 GO:0006898 GO:0006940 GO:0007165 GO:0007166 GO:0007171 GO:0007186 GO:0007188 GO:0007189 GO:0007190 GO:0007267 GO:0007565 GO:0007568 GO:0008144 GO:0008179 GO:0008284 GO:0008306 GO:0008333 GO:0009409 GO:0010765 GO:0015459 GO:0016020 GO:0016021 GO:0016324 GO:0016525 GO:0019899 GO:0030279 GO:0030424 GO:0030425 GO:0030501 GO:0031398 GO:0031649 GO:0031713 GO:0032403 GO:0032570 GO:0032781 GO:0032809 GO:0033574 GO:0035240 GO:0035249 GO:0035255 GO:0035811 GO:0040015 GO:0042060 GO:0042312 GO:0042383 GO:0042803 GO:0043065 GO:0043197 GO:0043231 GO:0043235 GO:0043268 GO:0043410 GO:0043627 GO:0044849 GO:0045453 GO:0045823 GO:0045909 GO:0045944 GO:0045986 GO:0048633 GO:0050728 GO:0050873 GO:0051379 GO:0051380 GO:0051924 GO:0051930 GO:0060079 GO:0071456 GO:0071548 GO:0071867 GO:0071880 GO:0090331 GO:0097421 GO:1901098 GO:1904504 GO:1904925
140.070.5994.010.060.954mbsA GO:0000165 GO:0001618 GO:0002407 GO:0003779 GO:0004435 GO:0004871 GO:0004930 GO:0004950 GO:0005506 GO:0005737 GO:0005768 GO:0005886 GO:0005887 GO:0006816 GO:0006935 GO:0006954 GO:0006955 GO:0006968 GO:0007165 GO:0007166 GO:0007186 GO:0007204 GO:0007267 GO:0009055 GO:0009897 GO:0009986 GO:0014808 GO:0015026 GO:0016020 GO:0016021 GO:0016032 GO:0016493 GO:0019064 GO:0019722 GO:0019957 GO:0023052 GO:0030260 GO:0046872 GO:0055114 GO:0070098 GO:0070723 GO:0071222 GO:0071791
150.070.5824.380.060.963uonA GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006940 GO:0007165 GO:0007186 GO:0007187 GO:0007188 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007399 GO:0008016 GO:0008144 GO:0008152 GO:0009253 GO:0009615 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019835 GO:0030054 GO:0030425 GO:0030430 GO:0032279 GO:0032280 GO:0042742 GO:0043025 GO:0043679 GO:0045202 GO:0045211
160.070.5774.050.090.954ib4A GO:0001755 GO:0001819 GO:0001938 GO:0001965 GO:0002031 GO:0003007 GO:0003300 GO:0004871 GO:0004930 GO:0004993 GO:0005096 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006182 GO:0006874 GO:0006939 GO:0007165 GO:0007186 GO:0007202 GO:0007205 GO:0007210 GO:0007507 GO:0007610 GO:0008144 GO:0008284 GO:0009055 GO:0010507 GO:0010513 GO:0014033 GO:0014065 GO:0014827 GO:0016020 GO:0016021 GO:0016310 GO:0019722 GO:0020037 GO:0022900 GO:0030054 GO:0030425 GO:0034220 GO:0035733 GO:0042310 GO:0042493 GO:0042597 GO:0043005 GO:0043025 GO:0043066 GO:0043123 GO:0043406 GO:0043547 GO:0043647 GO:0045202 GO:0046872 GO:0048598 GO:0050715 GO:0050795 GO:0051000 GO:0051209 GO:0051378 GO:0051781 GO:0055114 GO:0060548 GO:0070371 GO:0070374 GO:0070528 GO:0071418 GO:0071502 GO:1904015
170.070.5904.070.050.914dklA GO:0001965 GO:0002438 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004979 GO:0004985 GO:0005245 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0005925 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007194 GO:0007200 GO:0007204 GO:0007218 GO:0007268 GO:0007626 GO:0008022 GO:0008152 GO:0009253 GO:0009314 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019233 GO:0019835 GO:0019904 GO:0030425 GO:0030430 GO:0030818 GO:0031005 GO:0031635 GO:0031681 GO:0032094 GO:0032100 GO:0032496 GO:0032590 GO:0032839 GO:0033554 GO:0038003 GO:0038047 GO:0042060 GO:0042220 GO:0042383 GO:0042742 GO:0042755 GO:0042923 GO:0043005 GO:0043204 GO:0043278 GO:0043950 GO:0043951 GO:0044849 GO:0045019 GO:0045121 GO:0045429 GO:0045471 GO:0048149 GO:0050769 GO:0051481 GO:0051930 GO:0060079 GO:0061358 GO:0070374 GO:0070588 GO:0070848 GO:0071315 GO:0098794 GO:2000310
180.070.5654.460.090.954iarA GO:0002031 GO:0004871 GO:0004930 GO:0004993 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007187 GO:0007198 GO:0007205 GO:0007268 GO:0007610 GO:0007631 GO:0008144 GO:0009055 GO:0014059 GO:0014063 GO:0016020 GO:0016021 GO:0020037 GO:0022900 GO:0030818 GO:0032229 GO:0035690 GO:0042220 GO:0042310 GO:0042493 GO:0042597 GO:0042756 GO:0045471 GO:0046849 GO:0046872 GO:0050795 GO:0051378 GO:0051385 GO:0051967 GO:0055114 GO:0071312 GO:0071502


Consensus prediction of GO terms
 
Molecular Function GO:0004930 GO:0035586 GO:0005515
GO-Score 0.37 0.33 0.33
Biological Processes GO:0050877 GO:0006952 GO:0098916 GO:0044765 GO:0006897 GO:0045762 GO:0007599 GO:0012501 GO:0007399 GO:0050817 GO:0035588 GO:0044260 GO:0019538 GO:0003013 GO:0010578 GO:0042060 GO:0007189
GO-Score 0.44 0.44 0.39 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33 0.33
Cellular Component GO:0005887
GO-Score 0.37

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]



Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.