Threading Zmax Znorm MUSTER 7.09 1.22 dPPAS 9.02 0.97 wdPPAS 20.50 2.20 wMUSTER 9.85 1.70 wPPAS 22.17 3.17 dPPAS2 22.34 2.13 PPAS 13.13 1.88 Env-PPAS 17.50 2.19 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.31 0.44+-0.14 11.3+-4.5 3275 0.051 model2 -3.09 1573 0.024 model3 -3.40 1063 0.017 model4 -3.36 1000 0.018 model5 -4.00 543 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).