Threading Zmax Znorm MUSTER 4.85 0.84 dPPAS 7.33 0.79 wdPPAS 5.64 0.61 wMUSTER 4.63 0.80 wPPAS 5.41 0.77 dPPAS2 15.63 1.49 PPAS 6.29 0.90 Env-PPAS 5.89 0.74 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.14 0.46+-0.15 11.6+-4.5 3609 0.135 model2 -3.22 1768 0.046 model3 -3.99 750 0.021 model4 -5.00 346 0.004 model5 -5.00 304 0.003 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).