Threading Zmax Znorm MUSTER 5.58 0.96 dPPAS 7.38 0.79 wdPPAS 8.67 0.93 wMUSTER 5.92 1.02 wPPAS 8.04 1.15 dPPAS2 13.66 1.30 PPAS 8.51 1.22 Env-PPAS 5.60 0.70 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.93 0.48+-0.15 8.7+-4.5 10990 0.144 model2 -4.02 1966 0.018 model3 -4.57 1015 0.010 model4 -4.54 964 0.011 model5 -4.61 1106 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).