Threading Zmax Znorm MUSTER 7.88 1.36 dPPAS 12.65 1.36 wdPPAS 9.63 1.04 wMUSTER 7.90 1.36 wPPAS 8.09 1.16 dPPAS2 12.27 1.17 PPAS 9.01 1.29 Env-PPAS 11.05 1.38 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4008) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.32 0.55+-0.15 4.4+-2.9 2677 0.211 model2 -1.14 2300 0.253 model3 -1.48 1570 0.180 model4 -5.00 29 0.003 model5 -5.00 10 0.002 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).