I-TASSER results

I-TASSER results for job id Rv1491c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (252 residues)
MTAPAICNTTETVHGIATSLGAVARQASLPRIVGTVVGITVLVVVALLVPVPTAVELRDW
AKSLGAWFPLAFLLVHTVVTVPPFPRTAFTLAAGLLFGSVVGVFIAVVGSTASAVIAMLL
VRATGWQLNSLVRRRAINRLDERLRERGWLAILSLRLIPVVPFAAINYAAGASGVRILSF
AWATLAGLLPGTAAVVILGDAFAGSGSPLLILVSVCTGALGLTGLVYEIRNYRRQHRRMP
GYDDPVREPALI

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MTAPAICNTTETVHGIATSLGAVARQASLPRIVGTVVGITVLVVVALLVPVPTAVELRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAFTLAAGLLFGSVVGVFIAVVGSTASAVIAMLLVRATGWQLNSLVRRRAINRLDERLRERGWLAILSLRLIPVVPFAAINYAAGASGVRILSFAWATLAGLLPGTAAVVILGDAFAGSGSPLLILVSVCTGALGLTGLVYEIRNYRRQHRRMPGYDDPVREPALI
Prediction	CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
Conf.Score	998877776544455545555445578999999999999999999998657999999999999796889999999999998655689999999999978999999999999999999999999858999997558999999999986789999999975587699999998679997889999999999999999999999976887678999999999999999999999999998765556665567899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MTAPAICNTTETVHGIATSLGAVARQASLPRIVGTVVGITVLVVVALLVPVPTAVELRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAFTLAAGLLFGSVVGVFIAVVGSTASAVIAMLLVRATGWQLNSLVRRRAINRLDERLRERGWLAILSLRLIPVVPFAAINYAAGASGVRILSFAWATLAGLLPGTAAVVILGDAFAGSGSPLLILVSVCTGALGLTGLVYEIRNYRRQHRRMPGYDDPVREPALI
Prediction	864534454354244345434424333312211122233222232121131431630240057231111122232233322323233311331133333330231010000100020102022103300422455104201610674101010101121332333002000117143330000023133331100000021034343231122332333333333332223223445645657654753357
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MTAPAICNTTETVHGIATSLGAVARQASLPRIVGTVVGITVLVVVALLVPVPTAVELRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAFTLAAGLLFGSVVGVFIAVVGSTASAVIAMLLVRATGWQLNSLVRRRAINRLDERLRERGWLAILSLRLIPVVPFAAINYAAGASGVRILSFAWATLAGLLPGTAAVVILGDAFAGSGSPLLILVSVCTGALGLTGLVYEIRNYRRQHRRMPGYDDPVREPALI

4bwzA2

0.11

0.09

0.82

0.95

MUSTER

------------------RLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGFE-----------TLPALFLGTALVATSVGITARVLQELGVL--SRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQELS------ALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVGCGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE---------

4ke2A

0.11

0.08

0.78

1.12

dPPAS

-------------------------------------------------MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALETINVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAAATAVSAAAAAAAAAIAFAAAP-------

3wdoA2

0.18

0.13

0.73

1.16

wdPPAS

-------------RESGMVKGSFSKVLAEPRLLKLNFGIMCLHMLLMST----FVALPGQLADAGFEHWKVYLATMLIAFGSVVPFIIYAEVKR-----MKQVFVFCVGLIVVAEIVLWNA---QTQFWQLVVGVQLFFVAFNLME--LLPSLISKESPA-----KGTAMGV----STSQFLGVAIGGSLGGWIDGMFD----------GQGVFLAGAMLAAVWLAVASTM---------------------

3jd8A

0.11

0.96

1.05

wMUSTER

VKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMK--SCRRLLVDSKVSLGIAGILIVLSSVACSL---GVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAY-QRDERLQGETLDQQLGRVLGEVATVAFFLGALSVMPAVHTFSLFAGLA---FIDFAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLSMPDDSYMVDYFKSISQPPVYF

4hzuS

0.14

0.09

0.61

1.17

wPPAS

---------------------------------------------------MTKGSLKENTIAA--LIAMTVALSILVV--IPIPCEVGIYTSAILYGRRMGLLVGGASGFLIDILT------------------------------YPVWCLFSLVIHGTQGLVVGWLLPRHHKGIRSMLLPLLVGSLVMVIGYCLATTLLFGPAGLASIFGNVVQVGFGAGVTLSIVGPLTRLKPD--------------

4bwzA2

0.10

0.08

0.81

1.96

dPPAS2

------------------RLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGF-----------ETLPALFLGTALVATSVGITARVLQELGVL--SRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQELSALASPVVLVAGTVVTVIAILGKVLG---GFLGALTQG------VRSALTVGCGRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE---------

4bwzA2

0.09

0.08

0.81

1.30

PPAS

------------------RLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGF-----------ETLPALFLGTALVATSVGITARVLQELGVL--SRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQELSALASPVVLVAGTVVTVIAILGKVLG---GFLGALTQGV----RSALTVGCGMARGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE---------

3hqqX3

0.12

0.11

0.93

0.82

Env-PPAS

LSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARM-----NFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGRDIMNHQGVQNIDSIIEERGDLGVIPAEKVVVAQKILISKCNVAGKVICATQMLESMTNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAL-------------

4ikvA2

0.10

0.09

0.90

0.95

MUSTER

VGILGIIIPIIYFVVMYRSPKTAEERSRVIAYIPLFVASAMFWAIQEQGST----ILANYADKRTQLDVAGILSPAWFQSLNPLFIIILAPVFAWMWVKLGKRQPTIPQKFALGLLFAGLSFIVILVPGHLSGGGLVH-PIWLVLSYFIVVLGELCLSPVGLSATTKLAAAFSAQTMSLWFLSNAAAQAINAQLVRFY----TPENETAYFGTIGGAALVLGLILLAIAPRIGRLMK---------------

4bwzA2

0.12

0.10

0.82

1.09

dPPAS

---------------RLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLGTALVATSVGITARVLQELG-VLSRPYSRIILGAAVIDDVLGLIVLACVNGVAETG--------QELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVGCGMAP-------------RGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE---------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.80

Estimated TM-score = 0.39±0.13

Estimated RMSD = 12.4±4.3Å

Download Model 2

C-score=-3.58

Download Model 3

C-score=-3.81

Download Model 4

C-score=-3.59

Download Model 5

C-score=-4.16

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4bwzA	0.708	3.26	0.115	0.853
2	4czbA	0.666	3.70	0.082	0.841
3	4cz8A	0.642	3.66	0.099	0.814
4	1zcdA	0.639	3.63	0.098	0.786
5	4n7wA	0.624	3.93	0.065	0.821
6	3zuxA	0.605	4.14	0.051	0.825
7	4a01A	0.468	4.67	0.079	0.663
8	3dhiA	0.467	5.42	0.024	0.742
9	4av3A	0.452	5.97	0.057	0.770
10	1mhzD	0.451	5.47	0.033	0.722

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.06	3	1xvgA	BRJ	Rep, Mult	73,74,77,148,151,152
2	0.06	3	2fkwD	BCL	Rep, Mult	98,101
3	0.06	3	3zuyA	PTY	Rep, Mult	158,175,182,227,230,231,234
4	0.06	3	4v1fA	BQ1	Rep, Mult	113,114,117
5	0.04	2	2xqtD	CVM	Rep, Mult	102,105,109
6	0.02	1	2y02A	2CV	Rep, Mult	140,147
7	0.02	1	3u32K	DCW	Rep, Mult	75,113,120
8	0.02	1	3j47U	III	Rep, Mult	224,225,228
9	0.02	1	2q67A	CA	Rep, Mult	80,81
10	0.02	1	1vf5S	III	Rep, Mult	119,120
11	0.02	1	3zuxA	TCH	Rep, Mult	29,32,172,173,174,175
12	0.02	1	4amjB	2CV	Rep, Mult	68,128
13	0.02	1	4bo3B	U98	Rep, Mult	39,111,118,119
14	0.02	1	1xvfA	3CL	Rep, Mult	73,192,195,196
15	0.02	1	1kfyB	CE1	Rep, Mult	180,184
16	0.02	1	2wse4	CLA	Rep, Mult	72,76
17	0.02	1	3a0bZ	CLA	Rep, Mult	75,78
18	0.02	1	2y02A	2CV	Rep, Mult	213,216

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1pcaA	0.400	5.01	0.063	0.587	3.4.17.1	NA
2	0.060	2j2fA	0.444	5.61	0.038	0.710	1.14.19.2,1.14.99.6	NA
3	0.060	2bq1I	0.415	5.60	0.065	0.667	1.17.4.1	NA
4	0.060	3fg3A	0.400	6.67	0.062	0.754	4.2.1.92,1.13.11.40	NA
5	0.060	1fpsA	0.401	4.78	0.038	0.552	2.5.1.1,2.5.1.10	NA
6	0.060	1z1lA	0.379	5.36	0.031	0.587	3.1.4.17	114
7	0.060	2uw1B	0.429	5.55	0.033	0.686	1.14.99.6	184
8	0.060	1ayeA	0.404	5.01	0.102	0.591	3.4.17.15	NA
9	0.060	2fhbA	0.396	5.66	0.034	0.639	3.2.1.41	NA
10	0.060	1h8lA	0.409	5.39	0.059	0.651	3.4.17.22	85,192
11	0.060	1uwyA	0.412	5.46	0.043	0.659	3.4.17.12	105
12	0.060	2fknB	0.421	5.31	0.056	0.643	4.2.1.49	34
13	0.060	1g87B	0.401	5.73	0.068	0.667	3.2.1.4	NA
14	0.060	2fhcA	0.395	5.68	0.034	0.639	3.2.1.41	12
15	0.060	1fziA	0.449	5.53	0.033	0.722	1.14.13.25	NA
16	0.060	1mhyD	0.449	5.47	0.033	0.718	1.14.13.25	NA
17	0.060	3ffzA	0.417	5.36	0.075	0.663	3.4.24.69	NA
18	0.060	2vuaA	0.246	6.23	0.013	0.429	3.4.24.69	146,150
19	0.060	1pytA	0.185	4.77	0.023	0.266	3.4.17.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.12	0.708	3.26	0.12	0.85	4bwzA	GO:0006810 GO:0006812 GO:0015299 GO:0016020 GO:0016021 GO:0046872 GO:0055085 GO:1902600
1	0.11	0.670	3.69	0.09	0.85	4czbB	GO:0005886 GO:0006810 GO:0006811 GO:0006812 GO:0006814 GO:0015297 GO:0015299 GO:0016020 GO:0016021 GO:0042802 GO:0055085 GO:1902600
2	0.07	0.605	4.14	0.05	0.83	3zuxA	GO:0016020 GO:0016021
3	0.07	0.468	4.67	0.08	0.66	4a01A	GO:0004427 GO:0005773 GO:0005774 GO:0006810 GO:0006811 GO:0009678 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0046872 GO:0055085
4	0.07	0.452	6.07	0.06	0.78	4av3B	GO:0000287 GO:0004427 GO:0005509 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006814 GO:0009678 GO:0015081 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0030955 GO:0035725 GO:0042803 GO:0046872
5	0.07	0.463	5.97	0.08	0.81	4av6A	GO:0000287 GO:0004427 GO:0005509 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006814 GO:0009678 GO:0015081 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0030955 GO:0035725 GO:0042803 GO:0046872
6	0.06	0.655	3.56	0.10	0.82	4cz8A	GO:0006810 GO:0006812 GO:0015299 GO:0016020 GO:0016021 GO:0055085 GO:1902600
7	0.06	0.644	3.74	0.11	0.80	4atvA	GO:0005886 GO:0006810 GO:0006811 GO:0006814 GO:0006885 GO:0015081 GO:0015297 GO:0015491 GO:0015992 GO:0016020 GO:0016021 GO:0035725 GO:0055085 GO:0098655
8	0.06	0.329	5.46	0.05	0.51	3ug4C	GO:0005975 GO:0008152 GO:0016787 GO:0016798 GO:0046373 GO:0046556
9	0.06	0.318	5.99	0.07	0.54	3k5pA	GO:0004617 GO:0006564 GO:0008152 GO:0016491 GO:0016597 GO:0016616 GO:0051287 GO:0055114
10	0.06	0.624	3.93	0.07	0.82	4n7wA	GO:0016020 GO:0016021
11	0.06	0.276	6.24	0.08	0.48	4rpfA	GO:0000166 GO:0004413 GO:0005524 GO:0005737 GO:0006566 GO:0008652 GO:0009088 GO:0016301 GO:0016310 GO:0016740
12	0.06	0.260	6.26	0.04	0.46	1pv9B	GO:0005737 GO:0006508 GO:0008233 GO:0008237 GO:0016787 GO:0016805 GO:0046872 GO:0102009
13	0.06	0.279	4.45	0.08	0.38	2fckA	GO:0008080 GO:0016740 GO:0016746
14	0.06	0.271	5.77	0.06	0.44	4gmvB	GO:0005737 GO:0005856 GO:0005886 GO:0007165 GO:0016020 GO:0030027 GO:0030175 GO:0031252 GO:0042995 GO:0048675
15	0.06	0.277	5.96	0.04	0.48	1u0uA	GO:0003824 GO:0005737 GO:0008152 GO:0009058 GO:0016740 GO:0016746 GO:0016747 GO:0050198
16	0.06	0.253	5.26	0.07	0.38	2wlkA	GO:0005242 GO:0005244 GO:0006810 GO:0006811 GO:0006813 GO:0016020 GO:0016021 GO:0034765 GO:0071805
17	0.06	0.247	5.15	0.04	0.37	2wzr1	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0019012 GO:0019028 GO:0019030 GO:0019062 GO:0019082 GO:0030430 GO:0033644 GO:0034220 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0046718 GO:0051259
18	0.06	0.232	4.51	0.05	0.32	1flcB	GO:0001681 GO:0016020 GO:0016021 GO:0016032 GO:0016787 GO:0016788 GO:0019012 GO:0019031 GO:0019062 GO:0019064 GO:0020002 GO:0033644 GO:0039654 GO:0039663 GO:0046718 GO:0046789 GO:0055036

Consensus prediction of GO terms

Molecular Function	GO:0043169	GO:0015078	GO:0015298
GO-Score	0.47	0.43	0.43
Biological Processes	GO:0015992	GO:0098662	GO:0030001
GO-Score	0.43	0.43	0.33
Cellular Component	GO:0016021	GO:0071944
GO-Score	0.36	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.