I-TASSER results

I-TASSER results for job id Rv1433

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (271 residues)
MRAVFGCAIAVVGIAGSVVAGPADIHLVAAKQSYGFAVASVLPTRGQVVGVAHPVVVTFS
APITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSD
FKTGPAVVGVASISQHTFTVSIDGVEEGPPPPLPAPHHRVHFGEDGVMPASMGRPEYPTP
VGSYTVLSKERSVIMDSSSVGIPVDDPDGYRLSVDYAVRITSRGLYVHSAPWALPALGLE
NVSHGCISLSREDAEWYYNAVDIGDPVIVQE

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MRAVFGCAIAVVGIAGSVVAGPADIHLVAAKQSYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEEGPPPPLPAPHHRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSSVGIPVDDPDGYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE
Prediction	CCEEEEEEEEEHCCCCCEHCCCEEEEEHCCCCCCCCCCEEEHCCCCCEEEHCEEEEEEHCCCCCCHHHHHHHHHEEEEHCCCCCCEEEEEHCCCEEEEEHCCCCCCCEEEEEEHCCCCCCCCCCCCEEEEEHCCCCCEEEEHCCEEEEEEEEEHCCCEEEEEEHCCEEEEEHCCCCCCCCCEEEEEEEEHCCCEHCCCCCCCCCCCCCCCCCCCCCEEEHCCCCEEHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHCC
Conf.Score	9858999999985898655555578876688777765457875899588854789999688888767789887535787589988699996798899984768999858999976777655678858987645655558886665655667776554588998788899886799999997689999965775657888889999998877888775885799599868889865578888876667899899999999789995899959
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MRAVFGCAIAVVGIAGSVVAGPADIHLVAAKQSYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEEGPPPPLPAPHHRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSSVGIPVDDPDGYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE
Prediction	7424030201031443543545341332325454423213030454320000010003034314555425202530404154614021212456203020652145524030333344343431421102233444432023333444332313243333202462100000325734024120202223443304243232346344213130300020122000000021324433434110010103361043005206451303048
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCEEEEEEEEEHCCCCCEHCCCEEEEEHCCCCCCCCCCEEEHCCCCCEEEHCEEEEEEHCCCCCCHHHHHHHHHEEEEHCCCCCCEEEEEHCCCEEEEEHCCCCCCCEEEEEEHCCCCCCCCCCCCEEEEEHCCCCCEEEEHCCEEEEEEEEEHCCCEEEEEEHCCEEEEEHCCCCCCCCCEEEEEEEEHCCCEHCCCCCCCCCCCCCCCCCCCCCEEEHCCCCEEHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHCC
MRAVFGCAIAVVGIAGSVVAGPADIHLVAAKQSYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEEGPPPPLPAPHHRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSSVGIPVDDPDGYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4k73A

0.99

0.80

0.82

2.84

MUSTER

--------------------------------SYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEE--------GPPRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSS----------GYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4k73A

0.97

0.79

0.82

3.51

dPPAS

--------------------------------SYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDG--------VEEGPPRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSG----------YRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4jmnA

0.50

0.39

0.78

4.60

wdPPAS

---------------------------------PIPGVASVSPANGAVVGVAHPVVVTFTTPVTD---RRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDA----------------------LIGVASISAHTFTVSRNGTMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV-

4k73A

0.96

0.78

0.81

3.35

wMUSTER

---------------------------------YGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEE--------GPPRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSGYRLS----------VDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4jmnA

0.50

0.39

0.78

4.79

wPPAS

-----------------------------PI----PGVASVSPANGAVVGVAHPVVVTFTTPVTD---RRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDA----------------------LIGVASISAHTFTVSRNGTMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV-

4k73A

0.97

0.79

0.82

6.50

dPPAS2

--------------------------------SYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDG--------VEEGPPRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSG----------YRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4k73A

0.97

0.79

0.82

4.19

PPAS

--------------------------------SYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDG--------VEEGPPRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSS----------GYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE

4jmnA

0.54

0.43

0.80

6.00

Env-PPAS

---------------------------------PIPGVASVSPANGAVVGVAHPVVVTFTTPVTD---RRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNG----------------EVLR--TMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV-

4jmnA

0.54

0.43

0.80

2.78

MUSTER

---------------------------------PIPGVASVSPANGAVVGVAHPVVVTFTTPVTD---RRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNG----------------EVLR--TMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV-

4jmnA

0.54

0.43

0.80

3.49

dPPAS

---------------------------------PIPGVASVSPANGAVVGVAHPVVVTFTTPVTD---RRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNG------------------EVLRTMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV-

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.51

Estimated TM-score = 0.65±0.13

Estimated RMSD = 7.1±4.1Å

Download Model 2

C-score=-1.66

Download Model 3

C-score=-3.00

Download Model 4

C-score=-0.98

Download Model 5

C-score=-2.92

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4k73A	0.801	0.92	0.995	0.816
2	4jmnA	0.756	1.53	0.532	0.797
3	4xvoA	0.717	1.85	0.533	0.775
4	3vaeA	0.708	2.53	0.378	0.801
5	4z7aA	0.652	3.15	0.267	0.767
6	1zatA	0.477	3.40	0.143	0.557
7	3ujzA	0.456	5.82	0.074	0.720
8	1y7mA	0.450	3.36	0.160	0.528
9	2ocwA	0.422	5.25	0.097	0.631
10	2qtvA	0.419	5.55	0.063	0.664

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.21	7	4jmxA	IM2	Rep, Mult	195,210,212,224,228,232,243,244,245,246,248
2	0.06	2	1exvA	700	Rep, Mult	248,256,260
3	0.06	2	3cemA	AVD	Rep, Mult	227,228,253
4	0.06	2	2fkwD	BCL	Rep, Mult	264,267
5	0.04	1	4k73A	CA	Rep, Mult	48,49,262
6	0.03	1	3re0A	CPT	Rep, Mult	237,246
7	0.03	1	3bd7A	CKB	Rep, Mult	230,251,252
8	0.03	1	3cejA	AVF	Rep, Mult	215,217,218,227

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	3flcX	0.385	6.55	0.062	0.694	2.7.1.30	194,217
2	0.060	2vsfA	0.389	5.95	0.051	0.649	3.6.4.12	17
3	0.060	2zf5Y	0.380	6.68	0.039	0.697	2.7.1.30	227,230
4	0.060	1aupA	0.368	6.48	0.039	0.642	1.4.1.2	265
5	0.060	1b26A	0.391	6.19	0.057	0.657	1.4.1.3	122,265
6	0.060	1e1yA	0.353	6.75	0.044	0.638	2.4.1.1	NA
7	0.060	1n63B	0.384	6.73	0.046	0.712	1.2.99.2	NA
8	0.060	2c4mC	0.400	6.33	0.056	0.679	2.4.1.1	NA
9	0.060	1rtkA	0.361	6.50	0.072	0.646	3.4.21.47	230,254,256
10	0.060	1fa9A	0.313	5.98	0.049	0.513	2.4.1.1	NA
11	0.060	3gpbA	0.315	5.83	0.049	0.513	2.4.1.1	NA
12	0.060	1w0iA	0.385	6.56	0.048	0.697	2.3.1.41	NA
13	0.060	1rs0A	0.360	6.37	0.077	0.635	3.4.21.47	222
14	0.060	1b3bE	0.391	6.15	0.049	0.646	1.4.1.3	NA
15	0.060	1ygpA	0.385	6.35	0.048	0.660	2.4.1.1	176
16	0.060	1ox0A	0.390	5.67	0.066	0.620	2.3.1.41	NA
17	0.060	2qllA	0.325	6.69	0.048	0.605	2.4.1.1	NA
18	0.060	2ix4A	0.391	6.05	0.049	0.649	2.3.1.41	3
19	0.060	1bvuA	0.392	6.19	0.057	0.657	1.4.1.3	122,265

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.65	0.801	0.92	0.99	0.82	4k73A	GO:0008360 GO:0009252 GO:0016740 GO:0016746 GO:0071555
1	0.56	0.734	1.84	0.54	0.79	4xvoA	GO:0016740
2	0.51	0.756	1.53	0.53	0.80	4jmnA	GO:0005576 GO:0006508 GO:0008360 GO:0009252 GO:0016740 GO:0016746 GO:0018104 GO:0042597 GO:0071555 GO:0071972
3	0.29	0.698	2.98	0.33	0.82	4qr7A	GO:0005886 GO:0008360 GO:0009252 GO:0016020 GO:0016740 GO:0016746 GO:0046872 GO:0071555
4	0.19	0.652	3.15	0.27	0.77	4z7aA	GO:0016740
5	0.19	0.427	4.18	0.14	0.55	4a52A	GO:0008360 GO:0009252 GO:0016740 GO:0016757 GO:0016787 GO:0030435 GO:0031160 GO:0071555
6	0.13	0.419	3.73	0.14	0.51	4xxtA	GO:0004180 GO:0006508 GO:0016740 GO:0016787
7	0.13	0.474	3.62	0.14	0.56	2hklA	GO:0016020 GO:0016021 GO:0016740
8	0.12	0.406	2.20	0.14	0.44	5bmqA	GO:0016020 GO:0016021 GO:0016740
9	0.06	0.318	6.54	0.04	0.56	1rf4A	GO:0003824 GO:0003866 GO:0005737 GO:0008652 GO:0009073 GO:0009423 GO:0016740 GO:0016765
10	0.06	0.254	6.32	0.02	0.45	3d2lC	GO:0008168 GO:0016740 GO:0032259
11	0.06	0.256	6.69	0.04	0.47	1bh3A	GO:0006810 GO:0006811 GO:0009279 GO:0015288 GO:0016020 GO:0016021 GO:0046930 GO:0055085
12	0.06	0.391	3.06	0.10	0.45	4lzhA	GO:0016740
13	0.06	0.244	6.63	0.04	0.44	3ga9L	GO:0003840 GO:0006508 GO:0006749 GO:0008233 GO:0009405 GO:0016740 GO:0016787 GO:0045227
14	0.06	0.201	6.19	0.09	0.34	4a3bG	GO:0000291 GO:0000932 GO:0001172 GO:0003676 GO:0003697 GO:0003727 GO:0003899 GO:0003968 GO:0005634 GO:0005665 GO:0005737 GO:0006351 GO:0006366 GO:0006367 GO:0031369 GO:0045948 GO:0060213
15	0.06	0.133	4.28	0.02	0.18	3ob9D	GO:0003677 GO:0005634 GO:0005654 GO:0006338 GO:0006342 GO:0006351 GO:0006355 GO:0016568 GO:0016575 GO:0035064 GO:0035267 GO:0043968 GO:0043984 GO:0072487
16	0.06	0.107	2.81	0.02	0.13	2n5jA	GO:0000294 GO:0000932 GO:0001525 GO:0001933 GO:0002230 GO:0002376 GO:0003677 GO:0003682 GO:0003723 GO:0003729 GO:0003730 GO:0003824 GO:0004518 GO:0004519 GO:0004521 GO:0004532 GO:0004540 GO:0005634 GO:0005654 GO:0005737 GO:0005783 GO:0005791 GO:0005856 GO:0005886 GO:0006508 GO:0006915 GO:0006954 GO:0007275 GO:0007399 GO:0008152 GO:0008233 GO:0008234 GO:0010468 GO:0010508 GO:0010595 GO:0010628 GO:0010629 GO:0010656 GO:0010884 GO:0010942 GO:0016020 GO:0016579 GO:0016787 GO:0030154 GO:0030867 GO:0032088 GO:0032715 GO:0032720 GO:0034599 GO:0035198 GO:0035613 GO:0035925 GO:0036459 GO:0042149 GO:0042307 GO:0042347 GO:0042406 GO:0043022 GO:0043124 GO:0044828 GO:0045019 GO:0045600 GO:0045766 GO:0045944 GO:0046872 GO:0050713 GO:0051259 GO:0055118 GO:0061014 GO:0061158 GO:0071222 GO:0071347 GO:0071356 GO:0090501 GO:0090502 GO:0090503 GO:0098586 GO:1900016 GO:1900119 GO:1900165 GO:1900745 GO:1902714 GO:1903799 GO:1903936 GO:1904468 GO:1904628 GO:1904637 GO:1990869 GO:2000379 GO:2000627

Consensus prediction of GO terms

Molecular Function	GO:0016746	GO:0043169	GO:0071972
GO-Score	0.88	0.57	0.51
Biological Processes	GO:0071555	GO:0008360	GO:0018104	GO:0006508
GO-Score	0.88	0.88	0.51	0.51
Cellular Component	GO:0071944	GO:0005576	GO:0042597
GO-Score	0.57	0.51	0.51

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.