Threading Zmax Znorm MUSTER 6.71 1.16 dPPAS 11.96 1.29 wdPPAS 22.24 2.39 wMUSTER 9.42 1.62 wPPAS 25.79 3.68 dPPAS2 29.17 2.78 PPAS 16.52 2.36 Env-PPAS 30.37 3.80 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=1506) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.70 0.40+-0.14 13.5+-4.0 236 0.028 model2 -2.31 204 0.042 model3 -2.74 178 0.027 model4 -1.13 163 0.135 model5 -3.00 141 0.021 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).