Threading Zmax Znorm MUSTER 4.90 0.85 dPPAS 8.06 0.87 wdPPAS 8.00 0.86 wMUSTER 5.43 0.94 wPPAS 6.02 0.86 dPPAS2 13.51 1.29 PPAS 6.33 0.91 Env-PPAS 6.56 0.82 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.05 0.58+-0.14 6.5+-3.9 13469 0.380 model2 -3.59 1137 0.030 model3 -4.48 469 0.012 model4 -4.86 373 0.008 model5 -4.40 534 0.013 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).