Threading Zmax Znorm MUSTER 3.96 0.68 dPPAS 5.98 0.64 wdPPAS 5.84 0.63 wMUSTER 4.63 0.80 wPPAS 5.29 0.76 dPPAS2 13.15 1.25 PPAS 5.46 0.78 Env-PPAS 5.60 0.70 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.40 0.43+-0.14 11.0+-4.6 8386 0.116 model2 -2.85 5210 0.074 model3 -4.11 676 0.021 model4 -4.80 657 0.011 model5 -3.22 3336 0.051 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).