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I-TASSER results for job id Rv1303

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)
 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)
  Ligand binding sites

Rank C-score Cluster
size		 PDB
Hit		 Lig
Name		 Download
Complex		 Ligand Binding Site Residues
10.21 15 3b71A III Rep, Mult 29,32,120,123,127
20.12 10 4xefD III Rep, Mult 21,25,28,32,35,120,123,127,130
30.08 7 3b71B III Rep, Mult 53,57,60,89,92,93,96,97,99
40.02 2 2wscL CLA Rep, Mult 76,89,90
50.02 2 3waqA FEO Rep, Mult 24,62,63,66,81,85,128,129,133
60.01 1 2einC CDL Rep, Mult 49,53,56
70.01 1 1rwtB CLA Rep, Mult 114,117
80.01 1 1ow6A III Rep, Mult 87,90,91,94,97
90.01 1 3d1lA MPR Rep, Mult 114,140
100.01 1 3c9iA XE Rep, Mult 97,101
110.01 1 3u3cA III Rep, Mult 21,24,25,28,130
120.01 1 4xpxA FE2 Rep, Mult 24,62,66,133
130.01 1 1q90M BCR Rep, Mult 93,97
140.01 1 2fkwD BCL Rep, Mult 107,110
150.01 1 2eikC CD Rep, Mult 31,35,116,120
160.01 1 2wsfL CLA Rep, Mult 89,90
170.01 1 4ryoA MPG Rep, Mult 29,47,54
180.01 1 1xrmA III Rep, Mult 130,133

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit		TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.2473gm1B0.6342.670.0890.7832.7.10.2123
20.1411tqgA0.4773.030.0780.6272.7.13.390,98
30.1242kk1A0.5182.870.0830.6582.7.10.263
40.1143eziA0.4813.030.0490.6332.7.13.3NA
50.0661i5nD0.4782.840.0410.6032.7.13.353
60.0602wbiB0.5494.150.0570.7831.3.99.-52
70.0601udyA0.5444.150.0650.7951.3.99.3NA
80.0602nyfA0.5854.510.0570.8884.3.1.5108
90.0601m56A0.5403.760.0390.7641.9.3.1NA
100.0601q0mD0.5542.720.0440.6961.15.1.154,62,123
110.0602ohyB0.5634.710.0910.8885.4.3.6NA
120.0602o6yA0.5774.660.0710.8824.3.1.-NA
130.0601w27A0.6094.600.0320.9384.3.1.24NA
140.0602ix6E0.5544.240.0650.8141.3.3.6NA
150.0603czoB0.5824.750.0510.9324.3.1.3NA
160.0602occN0.5454.700.0570.8881.9.3.1117
170.0603gzhA0.5464.110.0510.8074.3.2.2NA
180.0602z1qB0.5414.360.0700.8071.3.99.3NA
190.0601xmeA0.5663.580.1000.7891.9.3.1NA
200.0601c3cA0.5414.030.0500.8014.3.2.2NA
210.0601occA0.5464.690.0640.8881.9.3.1NA
220.0601k04A0.5073.130.0650.6402.7.10.2126,130
230.0601y2mB0.5874.620.0780.9014.3.1.24NA
240.0602pfmA0.5444.020.0600.8014.3.2.278

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.200.6243.340.070.812l6fA GO:0000166 GO:0001525 GO:0001725 GO:0002020 GO:0004198 GO:0004672 GO:0004713 GO:0004715 GO:0004871 GO:0005178 GO:0005524 GO:0005623 GO:0005634 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0006468 GO:0006508 GO:0007015 GO:0007155 GO:0007160 GO:0007172 GO:0007173 GO:0007275 GO:0008270 GO:0008284 GO:0009268 GO:0010812 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0017166 GO:0018108 GO:0021852 GO:0030054 GO:0031234 GO:0031953 GO:0032092 GO:0035994 GO:0038083 GO:0042383 GO:0042802 GO:0044319 GO:0045087 GO:0046777 GO:0046872 GO:0048471 GO:0051894 GO:0060055 GO:0061098 GO:1904237 GO:2000811
10.190.6252.880.100.794xevA GO:0000165 GO:0000166 GO:0000302 GO:0001525 GO:0001556 GO:0001666 GO:0001954 GO:0002040 GO:0002250 GO:0002315 GO:0002376 GO:0002688 GO:0004672 GO:0004683 GO:0004713 GO:0004715 GO:0004871 GO:0004972 GO:0005102 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0005938 GO:0006461 GO:0006468 GO:0006915 GO:0006950 GO:0006968 GO:0006970 GO:0007015 GO:0007155 GO:0007165 GO:0007166 GO:0007172 GO:0007173 GO:0007204 GO:0007229 GO:0008284 GO:0008285 GO:0008360 GO:0009612 GO:0009725 GO:0009749 GO:0010226 GO:0010243 GO:0010595 GO:0010656 GO:0010752 GO:0010758 GO:0010976 GO:0014009 GO:0014069 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0017146 GO:0018108 GO:0030027 GO:0030054 GO:0030154 GO:0030155 GO:0030279 GO:0030307 GO:0030334 GO:0030335 GO:0030424 GO:0030425 GO:0030426 GO:0030500 GO:0030502 GO:0030826 GO:0030838 GO:0031175 GO:0031234 GO:0032270 GO:0032403 GO:0032960 GO:0033209 GO:0035235 GO:0035902 GO:0038083 GO:0042127 GO:0042220 GO:0042493 GO:0042542 GO:0042976 GO:0042995 GO:0043025 GO:0043066 GO:0043149 GO:0043267 GO:0043423 GO:0043507 GO:0043524 GO:0043534 GO:0043552 GO:0044297 GO:0045087 GO:0045121 GO:0045428 GO:0045429 GO:0045453 GO:0045471 GO:0045638 GO:0045727 GO:0045765 GO:0045766 GO:0045860 GO:0046330 GO:0046777 GO:0048010 GO:0048041 GO:0048471 GO:0050731 GO:0050848 GO:0051000 GO:0051279 GO:0051591 GO:0051592 GO:0051968 GO:0060291 GO:0060292 GO:0070098 GO:0070374 GO:0071300 GO:0071498 GO:0090630 GO:0097440 GO:2000058 GO:2000060 GO:2000114 GO:2000249 GO:2000310 GO:2000379 GO:2000463 GO:2000538 GO:2000573
20.180.6312.860.080.771k05B GO:0000165 GO:0000166 GO:0000226 GO:0001525 GO:0001568 GO:0001570 GO:0001725 GO:0001764 GO:0001890 GO:0001932 GO:0001934 GO:0003007 GO:0003779 GO:0004672 GO:0004713 GO:0004715 GO:0004871 GO:0005088 GO:0005102 GO:0005524 GO:0005634 GO:0005737 GO:0005815 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0005938 GO:0006468 GO:0006921 GO:0007172 GO:0007173 GO:0007179 GO:0007229 GO:0007275 GO:0007411 GO:0008284 GO:0008360 GO:0008432 GO:0009790 GO:0010594 GO:0010632 GO:0014068 GO:0016020 GO:0016301 GO:0016310 GO:0016324 GO:0016740 GO:0018108 GO:0019901 GO:0021955 GO:0022408 GO:0030010 GO:0030027 GO:0030054 GO:0030198 GO:0030335 GO:0031234 GO:0033628 GO:0038007 GO:0038083 GO:0038096 GO:0040023 GO:0042127 GO:0042169 GO:0043066 GO:0043087 GO:0043542 GO:0043547 GO:0043552 GO:0045087 GO:0045667 GO:0045860 GO:0046621 GO:0046777 GO:0048010 GO:0048013 GO:0048870 GO:0050771 GO:0051493 GO:0051893 GO:0051897 GO:0051964 GO:0060396 GO:0071560 GO:1900024 GO:2000060 GO:2000811
30.170.5873.110.060.761fntc GO:0000502 GO:0006508 GO:0008537 GO:0061136
40.150.6232.760.070.763t6gB GO:0001558 GO:0001726 GO:0004871 GO:0005730 GO:0005737 GO:0005829 GO:0005886 GO:0005925 GO:0007015 GO:0007155 GO:0007173 GO:0007186 GO:0007229 GO:0008283 GO:0008286 GO:0010595 GO:0015629 GO:0016477 GO:0017124 GO:0019901 GO:0030027 GO:0030054 GO:0030335 GO:0035729 GO:0042981 GO:0048008 GO:0048010 GO:0048011 GO:0048012 GO:0050851 GO:0050852 GO:0050853 GO:0051301 GO:0060326
50.150.6713.740.060.914iggB GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034332 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0051015 GO:0051149 GO:0051291 GO:0071681 GO:0090136 GO:0098641 GO:2000146 GO:2001045 GO:2001240 GO:2001241
60.140.6413.610.060.914k1nA GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
70.130.6103.430.060.801z7qc GO:0000502 GO:0006508 GO:0008537 GO:0061136
80.130.5903.050.060.764p9tA GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
90.080.4933.150.060.634onsC GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
100.080.6143.070.050.784k1oA GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
110.070.5843.550.090.803dyjA GO:0001726 GO:0003779 GO:0005178 GO:0005200 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0007016 GO:0007044 GO:0007155 GO:0009986 GO:0016020 GO:0017166 GO:0030054 GO:0030274 GO:0030866 GO:0032403 GO:0032587 GO:0042995 GO:0051015 GO:0070062 GO:0070527
120.070.6043.820.050.831st6A GO:0001725 GO:0002009 GO:0002162 GO:0003779 GO:0005198 GO:0005623 GO:0005737 GO:0005743 GO:0005856 GO:0005886 GO:0005903 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005916 GO:0005925 GO:0005927 GO:0007155 GO:0008013 GO:0015629 GO:0016020 GO:0017166 GO:0030018 GO:0030032 GO:0030054 GO:0030334 GO:0030486 GO:0031594 GO:0031625 GO:0034333 GO:0034394 GO:0042383 GO:0042803 GO:0043034 GO:0043234 GO:0043297 GO:0045121 GO:0045294 GO:0045296 GO:0048675 GO:0051015 GO:0051371 GO:0051393 GO:0070062 GO:0070527 GO:0090136 GO:0090636 GO:0090637 GO:0097110 GO:0098723 GO:1903561 GO:1990357
130.070.5063.210.060.661dowA GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
140.060.4523.290.070.591avoB GO:0000165 GO:0000209 GO:0000502 GO:0002223 GO:0002479 GO:0005654 GO:0005737 GO:0005829 GO:0006521 GO:0008537 GO:0010950 GO:0019884 GO:0031145 GO:0033209 GO:0038061 GO:0038095 GO:0043161 GO:0043488 GO:0050852 GO:0051436 GO:0051437 GO:0060071 GO:0061133 GO:0061136 GO:0070062 GO:0090090 GO:0090263 GO:2000045
150.060.3775.110.020.633hdlA GO:0004601 GO:0005576 GO:0006979 GO:0016491 GO:0020037 GO:0042744 GO:0046872 GO:0055114 GO:0098869
160.060.3754.740.060.601schA GO:0004601 GO:0005576 GO:0006979 GO:0016491 GO:0020037 GO:0042744 GO:0046872 GO:0055114 GO:0098869
170.060.3904.760.090.651cydA GO:0004090 GO:0005739 GO:0005759 GO:0006116 GO:0016491 GO:0043621 GO:0051262 GO:0055114
180.060.3385.320.030.584wy9A GO:0004871 GO:0007165 GO:0016020 GO:0016021


Consensus prediction of GO terms		 
Molecular Function GO:0005524 GO:0004715 GO:0004197 GO:0046914 GO:0032403 GO:0008092 GO:0050839 GO:0004970 GO:0004674 GO:0019904 GO:0005085 GO:0005102 GO:0019901
GO-Score 0.47 0.47 0.40 0.40 0.40 0.40 0.40 0.39 0.39 0.36 0.36 0.34 0.30
Biological Processes GO:0007173 GO:0007172 GO:0045087 GO:0038083 GO:0001525 GO:0008284 GO:0007229 GO:0048010 GO:0061097 GO:0051893 GO:0001954 GO:0007162 GO:1901890 GO:0051099 GO:0050731 GO:0090505 GO:0043393 GO:0021801 GO:1904235 GO:0009612 GO:0031952 GO:0001933 GO:0001764 GO:0021860 GO:1903393 GO:0006417 GO:0090279 GO:0071356 GO:0010038 GO:0036293 GO:0006809 GO:0010660 GO:0009746 GO:0043266 GO:0048246 GO:0046330 GO:1903707 GO:0006182 GO:2000403 GO:1901215 GO:1904407 GO:0030823 GO:0019722 GO:0006979 GO:0046683 GO:0051209 GO:0048167 GO:0034250 GO:0070168 GO:0051495 GO:0071396 GO:0030833 GO:0032526 GO:1903428 GO:0032878 GO:0043547 GO:0043279 GO:0030010 GO:0050999 GO:0050806 GO:1900449 GO:1903169 GO:0032412 GO:0030500 GO:0031328 GO:0019934 GO:0046849 GO:0031532 GO:0032770 GO:0043271 GO:0031032 GO:0097305 GO:0043523 GO:0032959 GO:0051054 GO:0032147 GO:0030279 GO:0001894 GO:0030038 GO:0002690 GO:0019221 GO:0045637 GO:0045927 GO:2000537 GO:0010628 GO:0010919 GO:0070372 GO:0010522 GO:0043506 GO:0043406 GO:0098815 GO:0032273 GO:0045666 GO:0051966 GO:0031346 GO:0002313 GO:0071229 GO:0014074 GO:0001558 GO:1904018 GO:0050805 GO:0048599 GO:0010557 GO:0048469 GO:0030802 GO:0034405 GO:0099601 GO:1900371 GO:2000278 GO:0046427 GO:0038094 GO:0051656 GO:0034446 GO:0010771 GO:0043062 GO:0050770 GO:0022407 GO:0001649 GO:0022411 GO:0033627 GO:0051963 GO:0097194 GO:0071559 GO:0007017 GO:0010977 GO:0014066 GO:0051647 GO:0009887 GO:0097485 GO:0051896 GO:0002431 GO:0048608 GO:0007178 GO:0002433 GO:0048640 GO:0071378 GO:0046620 GO:0007507 GO:0010498 GO:2000811 GO:0043552 GO:0008360 GO:2000060 GO:0010595 GO:0050851 GO:0038179 GO:0035728 GO:0032869
GO-Score 0.55 0.47 0.47 0.47 0.47 0.47 0.44 0.44 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.36 0.35 0.34 0.34 0.34 0.34 0.32 0.30 0.30 0.30 0.30
Cellular Component GO:0005925 GO:0031234 GO:0005829 GO:0030027 GO:0008328 GO:0044463 GO:0030425 GO:0060076 GO:0044297 GO:0030427 GO:0031981 GO:0099572 GO:0098857 GO:0045177 GO:0098590 GO:0048471 GO:0022624 GO:0005815 GO:0001725 GO:0005938
GO-Score 0.55 0.47 0.44 0.44 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.39 0.36 0.36 0.35 0.35 0.34 0.34 0.34

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]


Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.