I-TASSER results

I-TASSER results for job id Rv1255c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (202 residues)
MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREA
LRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIG
GEMAGRSEVIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE
FVVPIVTPASAAARKAGHPGPE

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE
Prediction	CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
Conf.Score	9988887567999999999999999999989655789999999899898999868999999999999999999999999975899999999999999999999796778877668866456788889999999999999867788777899999999999999977899978999999999999975677777778899999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE
Prediction	7665644555445422530140024002533144031420052061144214424641420011003211440152035215746401300130022003102534201000234445235414522420230033005414544643133002000210101011345436402420230022002233444465753558
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE

5d1wA

0.23

0.22

0.93

1.90

MUSTER

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPITTDSAPIITRASARLAPAFTDTWVATDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGV-----------

5d1wA

0.24

0.22

0.93

1.73

dPPAS

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPTTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGV-----------

5d1wA

0.24

0.22

0.93

2.12

wdPPAS

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPITTDSAPIITRASARLAPAFTDTWVATDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERGV------------

5d1wA

0.24

0.22

0.92

2.17

wMUSTER

IP----YAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDAVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPITTDSAPIITRASARLAPAFTDTWVATDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFA-HGV------------

5d1wA

0.24

0.22

0.92

2.49

wPPAS

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPITTDSAPIITRASARLAPAFTDWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFA-HGV------------

5d1wA

0.24

0.22

0.93

2.35

dPPAS2

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPTTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGV-----------

5d1wA

0.23

0.21

0.93

2.31

PPAS

---RIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDNVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKLITTDSAPIITRASARLAPAFTDTWVATTNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGV-----------

4gctA

0.15

0.13

0.87

2.65

Env-PPAS

I------------NRREEILQALAEMLENEGASRITTAKLAKQVGVSEAALYRHFPSKTRMFEGLIEFIEESLMSRINRIFDEEKDTLNRIRLVMQLLLAFAERNPGLTRILSGHALMFEERLRDRINQLFERIETSLRQILRSFPVDENILAAQLLGQVEGSLNRFKYLPTANFDEYWALLSAQIK---------------

3mnlA

0.20

0.18

0.91

1.84

MUSTER

LGS------EAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAGEPTDQYHIARVISDVWLSNLLAWRASATDVSKRLDLAVRLLIGDQD------------

3mnlA

0.19

0.17

0.91

1.65

dPPAS

------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAGEPTEDQYHIARVISDVWLSNLLRRASATDVSKRLDLAVRLLIGDQD------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.42

Estimated TM-score = 0.66±0.13

Estimated RMSD = 6.3±3.8Å

Download Model 2

C-score=-1.54

Download Model 3

C-score=-0.99

Download Model 4

C-score=-3.07

Download Model 5

C-score=-2.06

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5d1wA	0.893	1.16	0.223	0.931
2	2f07A	0.699	3.28	0.143	0.886
3	3mnlA	0.687	3.47	0.188	0.896
4	1rktA	0.682	3.28	0.106	0.881
5	4cgrA	0.668	3.64	0.172	0.891
6	2zb9A	0.665	3.28	0.159	0.852
7	3bjbB	0.662	3.41	0.199	0.847
8	2of7A	0.661	3.30	0.150	0.842
9	3bniA	0.657	2.78	0.166	0.807
10	3angC	0.656	3.39	0.196	0.842

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.09	19	5aqcB	5JB	Rep, Mult	24,101,102,127,130,157,160
2	0.09	15	5fmpA	NUC	Rep, Mult	35,36,37,38,48,52,57,58
3	0.08	15	5f08A	5TG	Rep, Mult	77,90,91,95,98,131,134,137,153,156,160,182
4	0.06	11	3zqlB	QNA	Rep, Mult	47,49,50,53,54
5	0.06	13	3btjA	DEQ	Rep, Mult	66,69,70,72,73,101,102,105,112,126
6	0.04	8	3angB	DCC	Rep, Mult	112,121,122,125,148,151,154,158,160,161
7	0.03	7	3angD	DCC	Rep, Mult	158,162,165,166,168,169
8	0.02	5	5cw8A	55X	Rep, Mult	24,69,72,73,98,101,102,105,107,134,154,157,160,164
9	0.02	4	3btjB	DEQ	Rep, Mult	109,112,165,166
10	0.02	3	3lsrA	QNA	Rep, Mult	8,36,37,38,42,48,49,52
11	0.01	3	1vi0A	DCC	Rep, Mult	66,69,70,98,101,112,117,124,128,131,132,135,150,151,153,154,157
12	0.01	2	3angA	DCC	Rep, Mult	166,169
13	0.01	3	3b6cA	SDN	Rep, Mult	157,160,161,164
14	0.01	2	2np5A	NDS	Rep, Mult	168,169,170,171,172
15	0.00	1	3angB	DCC	Rep, Mult	162,166,169,177,181
16	0.00	1	3angA	DCC	Rep, Mult	18,22,23,62
17	0.00	1	1bjyB	CTC	Rep, Mult	153,157,160
18	0.00	1	2id3B	CA	Rep, Mult	39,43
19	0.00	1	3lsjB	COA	Rep, Mult	180,183,184
20	0.00	1	2xptA	K	Rep, Mult	112,115,116,117

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1z0hB	0.337	5.37	0.023	0.545	3.4.24.69	65
2	0.060	3hi7A	0.450	5.30	0.037	0.752	1.4.3.22	NA
3	0.060	3fwnA	0.350	6.24	0.043	0.673	1.1.1.44	NA
4	0.060	2z1qB	0.450	5.43	0.056	0.752	1.3.99.3	NA
5	0.060	1qbaA	0.442	5.39	0.070	0.757	3.2.1.52	21,23,39
6	0.060	2e9bA	0.443	5.11	0.071	0.718	3.2.1.41	109,161
7	0.060	7reqB	0.443	4.59	0.098	0.663	5.4.99.2	NA
8	0.060	1e5dA	0.448	4.90	0.034	0.698	1.-.-.-	NA
9	0.060	1syyA	0.459	4.68	0.057	0.678	1.17.4.1	NA
10	0.060	1ea9C	0.442	5.00	0.058	0.708	3.2.1.54	21
11	0.060	2vuxB	0.428	4.51	0.057	0.629	1.17.4.1	NA
12	0.060	1d8cA	0.455	4.39	0.064	0.658	2.3.3.9	40
13	0.060	2aaaA	0.442	4.51	0.061	0.658	3.2.1.1	18,21
14	0.060	2w90B	0.453	5.27	0.024	0.748	1.1.1.44	NA
15	0.060	1jqoA	0.445	5.09	0.038	0.718	4.1.1.31	71,154
16	0.060	2taaA	0.448	4.65	0.054	0.683	3.2.1.1	18,56
17	0.060	1h0nA	0.441	4.55	0.062	0.653	1.17.4.1	NA
18	0.060	2z8yD	0.442	5.79	0.079	0.797	1.2.7.4,1.2.99.2	70,102
19	0.060	2np0A	0.460	4.96	0.032	0.718	3.4.24.69	175

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.41	0.891	1.28	0.23	0.94	5d1wD	GO:0003677 GO:0006351 GO:0006355
1	0.33	0.624	3.62	0.16	0.84	2g3bA	GO:0003677 GO:0006351 GO:0006355
2	0.32	0.657	2.78	0.17	0.81	3bniA	GO:0003677 GO:0006351 GO:0006355
3	0.30	0.699	3.28	0.14	0.89	2f07A	GO:0003677 GO:0006351 GO:0006355
4	0.28	0.559	4.28	0.14	0.83	4l62A	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355
5	0.26	0.664	3.40	0.13	0.88	2hytA	GO:0003677 GO:0006351 GO:0006355
6	0.24	0.528	4.61	0.10	0.77	3vprA	GO:0003677 GO:0006351 GO:0006355 GO:0042802
7	0.24	0.678	3.38	0.19	0.87	3bjbB	GO:0003677 GO:0006351 GO:0006355
8	0.23	0.575	4.14	0.14	0.81	3ppbA	GO:0003677 GO:0006351 GO:0006355
9	0.21	0.524	4.35	0.18	0.75	2qwtA	GO:0003677 GO:0006351 GO:0006355
10	0.21	0.529	4.77	0.11	0.80	3f1bA	GO:0003677 GO:0006351 GO:0006355
11	0.21	0.603	3.69	0.16	0.81	3vuqC	GO:0003677 GO:0006351 GO:0006355
12	0.21	0.627	3.99	0.17	0.86	5d18A	GO:0003677 GO:0006351 GO:0006355
13	0.20	0.590	3.94	0.13	0.82	4auxA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
14	0.20	0.675	3.62	0.18	0.90	4cgrA	GO:0003677 GO:0006351 GO:0006355
15	0.19	0.561	4.28	0.17	0.81	4nn1A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
16	0.19	0.501	4.47	0.15	0.77	3egqA	GO:0003677 GO:0006351 GO:0006355
17	0.19	0.627	3.95	0.14	0.87	2qibA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
18	0.19	0.541	4.54	0.09	0.80	3mvpA	GO:0003677 GO:0006351 GO:0006355
19	0.19	0.570	4.56	0.10	0.86	3lhqA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
20	0.17	0.608	4.19	0.13	0.88	3hggA	GO:0003677 GO:0006351 GO:0006355
21	0.17	0.511	4.37	0.17	0.76	2q24B	GO:0003677 GO:0006351 GO:0006355
22	0.17	0.604	3.48	0.13	0.81	4hkuA	GO:0003677 GO:0006351 GO:0006355
23	0.17	0.575	4.36	0.16	0.82	3he0C	GO:0003677 GO:0006351 GO:0006355
24	0.17	0.608	3.66	0.11	0.81	4mk6A	GO:0003677 GO:0006351 GO:0006355
25	0.16	0.542	4.72	0.17	0.86	3c2bA	GO:0003677 GO:0006351 GO:0006355
26	0.16	0.568	4.52	0.11	0.86	3qbmA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
27	0.15	0.570	4.65	0.11	0.86	3bcgA	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0008144 GO:0042493 GO:0043565 GO:0045892
28	0.15	0.546	4.58	0.07	0.82	2id6A	GO:0003677 GO:0006351 GO:0006355
29	0.15	0.628	3.95	0.14	0.88	3bhqA	GO:0003677 GO:0006351 GO:0006355
30	0.15	0.560	4.76	0.21	0.84	3pasB	GO:0003677 GO:0006351 GO:0006355
31	0.15	0.557	4.59	0.07	0.86	2rasB	GO:0003677 GO:0006351 GO:0006355
32	0.14	0.550	4.50	0.13	0.83	3npiA	GO:0003677 GO:0006351 GO:0006355
33	0.14	0.579	4.19	0.18	0.85	5f1jA	GO:0003677 GO:0006351 GO:0006355
34	0.14	0.560	4.72	0.07	0.85	2uxhA	GO:0003677 GO:0006351 GO:0006355
35	0.14	0.542	3.95	0.14	0.74	2o7tA	GO:0003677 GO:0006351 GO:0006355
36	0.13	0.642	3.76	0.17	0.88	3c07A	GO:0003677 GO:0006351 GO:0006355
37	0.12	0.508	4.73	0.07	0.77	3ccyA	GO:0003677 GO:0006351 GO:0006355
38	0.10	0.467	4.79	0.09	0.70	2iaiA	GO:0003677 GO:0006351 GO:0006355
39	0.10	0.665	3.28	0.16	0.85	2zb9A	GO:0003677 GO:0006351 GO:0006355
40	0.08	0.535	4.32	0.11	0.78	3cdlB	GO:0003677 GO:0006351 GO:0006355
41	0.08	0.613	4.01	0.18	0.86	3cwrA	GO:0003677 GO:0006351 GO:0006355
42	0.08	0.620	4.08	0.18	0.86	2zcxA	GO:0003677 GO:0006351 GO:0006355
43	0.07	0.585	4.12	0.15	0.84	4jl3C	GO:0003677 GO:0006351 GO:0006355
44	0.07	0.589	3.87	0.12	0.83	2iu5A	GO:0003677 GO:0006351 GO:0006355
45	0.07	0.576	3.94	0.14	0.82	2fq4A	GO:0003677 GO:0006351 GO:0006355
46	0.07	0.585	3.95	0.12	0.82	2raeA	GO:0003677 GO:0006351 GO:0006355
47	0.07	0.505	4.40	0.18	0.75	2rekB	GO:0003677 GO:0006351 GO:0006355
48	0.07	0.548	4.61	0.10	0.85	3dpjA	GO:0003677 GO:0006351 GO:0006355
49	0.07	0.504	4.54	0.13	0.75	2guhA	GO:0003677 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0044212	GO:1990837	GO:0001071
GO-Score	0.55	0.55	0.55
Biological Processes	GO:0006355
GO-Score	0.86
Cellular Component	GO:0044444
GO-Score	0.55

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.