Threading Zmax Znorm MUSTER 5.09 0.88 dPPAS 8.30 0.89 wdPPAS 5.03 0.54 wMUSTER 4.64 0.80 wPPAS 5.17 0.74 dPPAS2 15.81 1.51 PPAS 8.13 1.16 Env-PPAS 6.26 0.78 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.46 0.33+-0.11 14.3+-3.8 2707 0.035 model2 -3.47 2536 0.034 model3 -3.49 2033 0.033 model4 -4.01 1379 0.020 model5 -4.01 1762 0.020 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).