I-TASSER results

Input Sequence in FASTA format

>protein (198 residues)
MTAPSGSSGESAHDAAGGPPPVGERPPEQPIADAPWAPPASSPMANHPPPAYPPSGYPPA
YQPGYPTGYPPPMPPGGYAPPGYPPPGTSSAGYGDIPYPPMPPPYGGSPGGYYPEPGYLD
GYGPSQPGMNTMALVSLISALVGVLCCIGSIVGIVFGAIAINQIKQTREEGYGLAVAGIV
IGIATLLVYMIAGIFAIP

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MTAPSGSSGESAHDAAGGPPPVGERPPEQPIADAPWAPPASSPMANHPPPAYPPSGYPPAYQPGYPTGYPPPMPPGGYAPPGYPPPGTSSAGYGDIPYPPMPPPYGGSPGGYYPEPGYLDGYGPSQPGMNTMALVSLISALVGVLCCIGSIVGIVFGAIAINQIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
Conf.Score	999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999988888886588999999999987788999999999999998756788753589999999999999999999859
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MTAPSGSSGESAHDAAGGPPPVGERPPEQPIADAPWAPPASSPMANHPPPAYPPSGYPPAYQPGYPTGYPPPMPPGGYAPPGYPPPGTSSAGYGDIPYPPMPPPYGGSPGGYYPEPGYLDGYGPSQPGMNTMALVSLISALVGVLCCIGSIVGIVFGAIAINQIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP
Prediction	744364545643564445434464433554444444434544344543344433544334443443444344433443434433344433443334332332343334434232332332223334444421000000113213313333331220011023204554672300000012313333233333333324
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
MTAPSGSSGESAHDAAGGPPPVGERPPEQPIADAPWAPPASSPMANHPPPAYPPSGYPPAYQPGYPTGYPPPMPPGGYAPPGYPPPGTSSAGYGDIPYPPMPPPYGGSPGGYYPEPGYLDGYGPSQPGMNTMALVSLISALVGVLCCIGSIVGIVFGAIAINQIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP

4ke2A

0.09

0.98

1.12

MUSTER

MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAASAAKALETINVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAA---AAKAAATAVSAAAAAAAAAIAFAAAP

1mv3A

0.10

0.98

1.22

dPPAS

VNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEG----WLMGVKESDWNQHKKLEKCRGVFP

1mv3A

0.12

0.11

0.88

1.33

wdPPAS

VNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ----LQL--------GVVL-VIPFQNPEEQDE-GMGKKLEK---GVF------ENFTERVP

2pffA

0.18

0.13

0.74

1.25

wMUSTER

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG---------------------------------GGGGGGGGGG-GG---G---------------G

1mv3A

0.15

0.14

0.89

2.39

wPPAS

AATPEIRVNHEPEPAGGATPGATPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLGFMFKVQAQLQL--------GVVL-VIPFQNPEEQDE-GMGKKLEK---GVF---ENFT-----VP

5gaoE

0.11

1.00

1.64

dPPAS2

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

1mv3A

0.10

0.09

0.92

2.34

PPAS

VNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQVVLVIPFQNPEEQDEGWLMGVKESDWNQHKKLEKRGVFPENFT----------------VP

1f16A

0.08

0.07

0.90

0.66

Env-PPAS

--------------------MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFWQTVTIFVAGVLTASLTI

1mv3A

0.10

0.99

1.10

MUSTER

AATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGVVLVIPFQNPEEQDEGW-LMGVKESDWNQHKKLEKCRGVFP

5gaoE

0.11

1.00

0.97

dPPAS

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-4.04

Estimated TM-score = 0.28±0.09

Estimated RMSD = 15.1±3.5Å

Download Model 2

C-score=-3.86

Download Model 3

C-score=-4.71

Download Model 4

C-score=-4.90

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1mv3A	0.796	2.89	0.104	0.970
2	5e6rA	0.356	5.26	0.039	0.586
3	4f1nA	0.332	4.84	0.030	0.520
4	3k71G	0.332	5.06	0.006	0.545
5	5fmwA	0.331	4.97	0.054	0.530
6	3jb9A	0.330	5.50	0.030	0.561
7	4abnA	0.324	4.72	0.066	0.495
8	2xr9A	0.323	5.07	0.047	0.515
9	4ui9I	0.320	5.77	0.035	0.571
10	4kkdA	0.317	4.87	0.057	0.500

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.05	2	3wmm7	BCL	Rep, Mult	183,187
2	0.05	2	4iuqA	CVM	Rep, Mult	138,156,196,197
3	0.02	1	3poyA	BGC	Rep, Mult	86,89,105
4	0.02	1	3fj5B	PG4	Rep, Mult	135,152,153
5	0.02	1	1rcjA	MA4	Rep, Mult	131,157,159,191
6	0.02	1	1y4jA	UUU	Rep, Mult	63,64
7	0.02	1	1mv0B	III	Rep, Mult	137,138,144,146,164,165,166,167,177,194,196
8	0.02	1	3lw5H	CLA	Rep, Mult	124,126
9	0.02	1	3k7tA	GP7	Rep, Mult	81,82
10	0.02	1	3prqX	CLA	Rep, Mult	141,148
11	0.02	1	3wmnF	BCL	Rep, Mult	154,181
12	0.02	1	3a0bZ	CLA	Rep, Mult	161,164
13	0.02	1	1jb0K	CLA	Rep, Mult	174,179
14	0.02	1	3m6oA	ZN	Rep, Mult	29,196
15	0.02	1	3mytB	EQU	Rep, Mult	61,62
16	0.02	1	1cq1B	CA	Rep, Mult	3,4
17	0.02	1	3rbhD	C8E	Rep, Mult	155,179
18	0.02	1	4mpoH	MG	Rep, Mult	95,96
19	0.02	1	2a68P	MG	Rep, Mult	181,185

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2qy0C	0.153	5.30	0.029	0.253	3.4.21.41,3.4.21.42	NA
2	0.060	1jxaA	0.280	5.49	0.026	0.480	2.6.1.16	NA
3	0.060	2bf4A	0.283	5.51	0.063	0.490	1.6.2.4	NA
4	0.060	1ut9A	0.287	4.82	0.054	0.455	3.2.1.4	NA
5	0.060	3fjoA	0.271	5.69	0.035	0.475	1.6.2.4	NA
6	0.060	1e1yA	0.235	6.14	0.015	0.444	2.4.1.1	NA
7	0.060	1soxA	0.281	4.91	0.048	0.439	1.8.3.1	NA
8	0.060	2qf7A	0.282	5.66	0.031	0.495	6.4.1.1	NA
9	0.060	3dwbA	0.280	5.77	0.039	0.505	3.4.24.71	NA
10	0.060	1mosA	0.205	6.43	0.047	0.394	2.6.1.16	NA
11	0.060	1vcnA	0.298	5.39	0.040	0.515	6.3.4.2	NA
12	0.060	1moqA	0.213	5.13	0.039	0.338	2.6.1.16	31
13	0.060	3fegA	0.287	5.19	0.051	0.475	2.7.1.82	122
14	0.060	2ad5B	0.298	5.32	0.017	0.515	6.3.4.2	NA
15	0.060	2qf7B	0.231	6.22	0.026	0.439	6.4.1.1	NA
16	0.060	2gajB	0.279	5.26	0.022	0.465	5.99.1.2	NA
17	0.060	1n1hA	0.280	5.52	0.052	0.490	2.7.7.48	NA
18	0.060	3es9B	0.258	4.85	0.024	0.399	1.6.2.4	NA
19	0.060	3gpbA	0.196	5.47	0.037	0.318	2.4.1.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.17	0.796	2.89	0.10	0.97	1mv3A	GO:0005634 GO:0005737 GO:0006897 GO:0006997 GO:0007275 GO:0008283 GO:0015629 GO:0016020 GO:0016032 GO:0030018 GO:0030100 GO:0030154 GO:0030315 GO:0030424 GO:0031674 GO:0033268 GO:0042692 GO:0042802 GO:0043065 GO:0043194 GO:0045664 GO:0048156 GO:0048711 GO:0051015 GO:0060987 GO:0060988 GO:0070063 GO:0071156
1	0.06	0.249	3.19	0.12	0.31	2e5kA	GO:0004721 GO:0004725 GO:0005634 GO:0005737 GO:0006469 GO:0009968 GO:0016787 GO:0035335 GO:0045670 GO:0045671 GO:0045779 GO:0051279 GO:0090331
2	0.06	0.257	3.11	0.04	0.32	1wxuA	GO:0000268 GO:0001561 GO:0001764 GO:0001967 GO:0002230 GO:0005777 GO:0005778 GO:0005779 GO:0006810 GO:0007626 GO:0015031 GO:0016020 GO:0016021 GO:0016560 GO:0021795 GO:0043231 GO:0060152 GO:0098779 GO:0098792
3	0.06	0.248	3.88	0.04	0.33	2vgeA	GO:0000122 GO:0003215 GO:0003229 GO:0003714 GO:0005634 GO:0005654 GO:0005737 GO:0005913 GO:0006351 GO:0006355 GO:0006915 GO:0008134 GO:0009791 GO:0030054 GO:0031076 GO:0035264 GO:0042633 GO:0042802 GO:0045171 GO:0045597 GO:0048871 GO:0060048 GO:0098609 GO:0098641 GO:1901796
4	0.06	0.252	2.82	0.07	0.30	2k9gA	GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005925 GO:0006897 GO:0006915 GO:0007010 GO:0007267 GO:0008360 GO:0016020 GO:0016477 GO:0017124 GO:0030054 GO:0030139 GO:0030659 GO:0031410 GO:0042059 GO:0043005 GO:0045202
5	0.06	0.245	3.11	0.07	0.30	1udlA	GO:0005070 GO:0005089 GO:0005509 GO:0005737 GO:0005813 GO:0006897 GO:0009967 GO:0030154 GO:0035023 GO:0043547 GO:0046872 GO:0070062 GO:1903861
6	0.06	0.241	3.81	0.03	0.32	4a63B	GO:0002039 GO:0005070 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0006915 GO:0007049 GO:0007165 GO:0017124 GO:0042802 GO:0042981 GO:0045786 GO:0048471 GO:0051059 GO:0072332 GO:1900119 GO:1900740 GO:1901216 GO:1901796
7	0.06	0.241	2.91	0.10	0.29	2ed0A	GO:0003677 GO:0005737 GO:0005829 GO:0005856 GO:0006928 GO:0007010 GO:0008093 GO:0008154 GO:0016032 GO:0016477 GO:0016601 GO:0017124 GO:0018108 GO:0019900 GO:0030027 GO:0030175 GO:0031209 GO:0031625 GO:0032403 GO:0042995 GO:0048365 GO:0070064 GO:2000601
8	0.06	0.240	2.74	0.14	0.29	2lj0A	GO:0001725 GO:0003779 GO:0005070 GO:0005158 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005856 GO:0005886 GO:0005899 GO:0005912 GO:0005913 GO:0005915 GO:0005924 GO:0005925 GO:0006810 GO:0006936 GO:0007015 GO:0007160 GO:0008092 GO:0008286 GO:0009967 GO:0015758 GO:0016020 GO:0016363 GO:0030054 GO:0032869 GO:0043149 GO:0045121 GO:0045725 GO:0046326 GO:0046889 GO:0048041 GO:0090004
9	0.06	0.243	2.75	0.10	0.29	2rf0A	GO:0000166 GO:0000186 GO:0003714 GO:0004672 GO:0004674 GO:0004706 GO:0004709 GO:0005524 GO:0005737 GO:0006468 GO:0006915 GO:0007165 GO:0007224 GO:0007254 GO:0007256 GO:0007257 GO:0008219 GO:0016301 GO:0016310 GO:0016740 GO:0018105 GO:0018107 GO:0042803 GO:0043065 GO:0043425 GO:0043433 GO:0043507 GO:0045892 GO:0046330 GO:0046777
10	0.06	0.221	2.94	0.11	0.27	2w10B	GO:0005634 GO:0005654 GO:0005737 GO:0005768
11	0.06	0.220	2.45	0.04	0.26	2a36A	GO:0001700 GO:0004871 GO:0005070 GO:0005118 GO:0005654 GO:0005737 GO:0005886 GO:0007015 GO:0007165 GO:0007175 GO:0007256 GO:0007265 GO:0007476 GO:0007613 GO:0007614 GO:0008293 GO:0008306 GO:0008355 GO:0008360 GO:0008595 GO:0016020 GO:0030707 GO:0038202 GO:0043410 GO:0045500 GO:0045678
12	0.06	0.228	2.83	0.08	0.27	2m0yA	GO:0002244 GO:0005085 GO:0005096 GO:0005634 GO:0005654 GO:0005737 GO:0006909 GO:0006915 GO:0007010 GO:0007264 GO:0010634 GO:0016020 GO:0016477 GO:0017124 GO:0032045 GO:0043547 GO:1900026
13	0.06	0.239	2.83	0.07	0.29	2lcsA	GO:0000173 GO:0000200 GO:0005737 GO:0006469 GO:0006972 GO:0009408 GO:0030674
14	0.06	0.232	3.23	0.08	0.29	3nmzC	GO:0005085 GO:0005089 GO:0005737 GO:0005829 GO:0005886 GO:0016020 GO:0019904 GO:0030032 GO:0030676 GO:0032587 GO:0035023 GO:0035556 GO:0042995 GO:0043065 GO:0043547 GO:0046847 GO:0051056
15	0.06	0.230	2.72	0.13	0.28	1k4uS	GO:0001669 GO:0002479 GO:0005730 GO:0005737 GO:0005829 GO:0006801 GO:0006968 GO:0008022 GO:0009055 GO:0016175 GO:0032010 GO:0042554 GO:0043020 GO:0045087 GO:0045454 GO:0045730 GO:0048010 GO:0048365 GO:0055114
16	0.06	0.220	2.74	0.07	0.26	1ujyA	GO:0005085 GO:0005089 GO:0005096 GO:0005622 GO:0005829 GO:0006915 GO:0007254 GO:0030027 GO:0030032 GO:0035023 GO:0042995 GO:0043065 GO:0043547 GO:0051056
17	0.06	0.233	2.43	0.11	0.27	2jteA	GO:0001726 GO:0005172 GO:0005730 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005938 GO:0007049 GO:0007067 GO:0008013 GO:0008022 GO:0016050 GO:0016337 GO:0016477 GO:0017124 GO:0030139 GO:0031252 GO:0031941 GO:0032403 GO:0032911 GO:0042995 GO:0043161 GO:0043234 GO:0045296 GO:0048259 GO:0048471 GO:0051301 GO:0070062 GO:1900182 GO:2000249
18	0.06	0.224	2.77	0.06	0.27	1s1nA	GO:0005198 GO:0005737 GO:0005829 GO:0005856 GO:0005911 GO:0005912 GO:0005923 GO:0005929 GO:0007165 GO:0007283 GO:0007588 GO:0007632 GO:0016020 GO:0016337 GO:0030030 GO:0030036 GO:0030054 GO:0030154 GO:0031514 GO:0032391 GO:0042995 GO:0048515 GO:0060041

Consensus prediction of GO terms

Molecular Function	GO:0032403	GO:0019899	GO:0003779
GO-Score	0.33	0.33	0.33
Biological Processes	GO:0060627	GO:0044764	GO:0043068	GO:0006996	GO:0051128	GO:0044403	GO:0048710	GO:0061061	GO:0045687	GO:0010564	GO:0034622	GO:0007050	GO:0030182	GO:0042981	GO:0065005
GO-Score	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33
Cellular Component	GO:0043231	GO:0005856	GO:0032994	GO:0030017	GO:0044304	GO:0044459	GO:0042383
GO-Score	0.54	0.33	0.33	0.33	0.33	0.33	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv1233c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]