Threading Zmax Znorm MUSTER 6.49 1.12 dPPAS 14.09 1.52 wdPPAS 24.61 2.65 wMUSTER 8.48 1.46 wPPAS 23.65 3.38 dPPAS2 31.67 3.02 PPAS 13.02 1.86 Env-PPAS 24.57 3.07 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=3012) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.22 0.45+-0.15 12.2+-4.4 704 0.048 model2 -2.32 622 0.044 model3 -2.67 487 0.031 model4 -2.96 320 0.023 model5 -3.39 240 0.015 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).