Threading Zmax Znorm MUSTER 5.23 0.90 dPPAS 6.94 0.75 wdPPAS 6.33 0.68 wMUSTER 4.58 0.79 wPPAS 5.78 0.83 dPPAS2 10.45 1.00 PPAS 6.45 0.92 Env-PPAS 6.61 0.83 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.11 0.46+-0.15 8.7+-4.5 11056 0.146 model2 -4.47 978 0.014 model3 -4.79 792 0.010 model4 -3.50 2577 0.036 model5 -4.94 629 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).