Threading Zmax Znorm MUSTER 4.25 0.73 dPPAS 7.31 0.79 wdPPAS 12.36 1.33 wMUSTER 4.97 0.86 wPPAS 9.66 1.38 dPPAS2 17.12 1.63 PPAS 7.28 1.04 Env-PPAS 10.38 1.30 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=9789) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.60 0.32+-0.11 16.4+-3.0 753 0.024 model2 -3.89 753 0.018 model3 -4.38 730 0.011 model4 -4.88 488 0.007 model5 -4.88 457 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).