Threading Zmax Znorm MUSTER 4.54 0.78 dPPAS 6.83 0.73 wdPPAS 8.12 0.87 wMUSTER 4.94 0.85 wPPAS 8.05 1.15 dPPAS2 11.19 1.07 PPAS 6.49 0.93 Env-PPAS 6.74 0.84 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.70 0.40+-0.14 9.5+-4.6 5973 0.075 model2 -3.07 4279 0.051 model3 -3.98 1819 0.021 model4 -4.45 758 0.013 model5 -4.18 1437 0.017 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).