I-TASSER results

I-TASSER results for job id Rv1059

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (354 residues)
MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGEIIGSPPLGVIAT
NSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVVTPLGWFYPSEKEAAPLEVAAQAG
NATLHGAGIGPGAVTELFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPD
SALTGPMQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEPGQVA
GRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEVRGSPDTCVTIKGWQ
PQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGIQSFFDLPLITGRAAPGLAR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGEIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVVTPLGWFYPSEKEAAPLEVAAQAGNATLHGAGIGPGAVTELFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGPMQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEPGQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEVRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGIQSFFDLPLITGRAAPGLAR
Prediction	CCCCCEEEEHCCCHHHHHHHHHHHHCCCCEEEEEEEHCHHHCCCCHHHHHCCCCCCEEEHCCHHHHHHCCCCEEEHCCCHHHHHHHHHHHHHCCCEEHCCCCCCCCHHHHHHHHHHHHHCCCEEEHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEHCCCCEEHCCEEHCCCEEEEEEEEEEEEHCCEEEEEEEEEEEHCCCCCCCCCCCCCCCCCEEEEEEHCCCEEEEEEHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	999848999868989999999999889967999999586777887889868888886886899999875998999879858999999999999979977887679999999999999996998998567887789999999999976775899999975666886689998868999966554554557644454899999999989955676899998885687567665898898799999999999999899999999997787788888888889858999996787799999768888888877776468888999888989987799866544468878877777789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGEIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVVTPLGWFYPSEKEAAPLEVAAQAGNATLHGAGIGPGAVTELFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGPMQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEPGQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEVRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGIQSFFDLPLITGRAAPGLAR
Prediction	872400000000120011004102735501000000235631021002004146140200220341152401000000144006201300624020000021112366115302500663400000000001100100000000002303301020001025241230023000002214424333344212201320021003104151355042424312054415132230431100001020202146312010202020236514261633675520201030404040303124264343442311010000010010021005020102000301012213133448
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCEEEEHCCCHHHHHHHHHHHHCCCCEEEEEEEHCHHHCCCCHHHHHCCCCCCEEEHCCHHHHHHCCCCEEEHCCCHHHHHHHHHHHHHCCCEEHCCCCCCCCHHHHHHHHHHHHHCCCEEEHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEHCCCCEEHCCEEHCCCEEEEEEEEEEEEHCCEEEEEEEEEEEHCCCCCCCCCCCCCCCCCEEEEEEHCCCEEEEEEHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGEIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVVTPLGWFYPSEKEAAPLEVAAQAGNATLHGAGIGPGAVTELFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGPMQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEPGQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEVRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGIQSFFDLPLITGRAAPGLAR

3ijpB

0.16

0.12

0.74

1.28

MUSTER

---SMRLTVVGAGRMGRELITAIQRRKDVELCAVLVRKSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIHIIGTTGF--SKTEEAQIADFAKYTTIVKMSLGVN--LLANLVKRAAKALDDDF-DIEIYEMHHANKVDSPS-------------------------GTALLLGQAAAEGRNIMLKNVSVNGRSGHTGKRKGTIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDV--------LGLN-

3ijpB

0.15

0.11

0.74

1.80

dPPAS

---SMRLTVVGNGRMGRELITAIQRRKDVELCAVLVRGSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAK-YTTIVKSGNMSLGNLLANLVKRAAKALDDDFDIEIYEMHHANKVDSP-------------------------SGTALLLGQAAAEGRNIMLKNVSVNGRSGHTGKREKTIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDVLGLN---------

3ijpB

0.16

0.12

0.73

2.12

wdPPAS

---SMRLTVVGAGRMGRELITAIQRRKDVELCAVLVRGSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAKYTTSGNMSLGVN--LLANLVKRAAKALDDDF-DIEIYEMHHANKVDSPS------G--------------------ALLLGQAAAEGRNIMLKNVSVNGRSGHTGKRE-TIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDLGLN----------

3ijpB

0.16

0.12

0.73

1.55

wMUSTER

----MRLTVVGAGRMGRELITAIQRRKDVELCAVLVRKSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAKYTTIVKMSLGVN--LLANLVKRAAKALDDDF-DIEIYEMHHANKVDSPS------G-------------------TALLLGQAAAEGRNIMLKNVSVNGRSGHTGKRKGTIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDV--------LGLN-

3ijpB

0.16

0.12

0.73

2.19

wPPAS

---SMRLTVVGNGRMGRELITAIQRRKDVELCAVLVRGSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAKYTTSGNMSLGVN--LLANLVKRAAKALDDDF-DIEIYEMHHANKVDSPS------G--------------------ALLLGQAAAEGRNIMLKNVSVNGRSGHTGKRE-TIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDLGLN----------

3ijpB

0.16

0.12

0.74

3.54

dPPAS2

---SMRLTVVGNGRMGRELITAIQRRKDVELCAVLVRGSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAK-YTTIVKSGNMSLGNLLANLVKRAAKALDDDFDIEIYEMHHANKVDSPS-------------------------GTALLLGQAAAEGRNIMLKNVSVNGRSGHTGKREKTIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDLGLN----------

3ijpB

0.16

0.12

0.73

2.03

PPAS

---SMRLTVVGNGRMGRELITAIQRRKDVELCAVLVRGSSFVDKDASILIGSDFLGVRITDDPESAFSNTEGILDFSQPQASVLYANYAAQKSLIIIGTTGF---SKTEEAQIADFAKYTT-IVKSGNMSLGNLLANLVKRAAKALDDDFDIEIYEMHHANKVDSPS------G--------------------ALLLGQAAAEGRNIMLKNVSVNGRSGHTGKRE-TIGFACSRGGTVIGDHSITFAGENERIVLSHIAQ---------------------------------------------------ERSIFANGALKAALWAKNHENGLYSMLDLGLN----------

1ebuA

0.15

0.13

0.88

0.97

Env-PPAS

STKVVNVAVIGAGVVGSAFLDQLLAMKSYNLVLLAEAEPLNVGSDWKAALAASTTKTLPLDDLIAHLKTSPKLVDNTSSAYIAGFYTKFVENGISIATPNKAFSSDLATWKALFSNKPTNGFVYHGAGL-P--IISFLREIIQTG-DEVEKIEGIEFSTSQANDVSDVVKVAKKLGYTEPDPRD----DLNGLDVARKVTIVGRISGVEVESPTSFPVQSLIPKPLESVKSADEFLEKLSDYDKDLTQLKKATENKVLRFIGKVDVATKSYSHPFASKGSDNVISIKTKRYTPVVIQGAG-----------AGAAVTAAGVLGDVIKIAQ---RL-------------------

5kt0A

0.17

0.13

0.73

1.28

MUSTER

--APIPVIVNGAGKMGREVVKAIAQAPDLNLLGAIDSSPEHQGKDAGELAGLSPLEVPITNQLEPMLGYPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGL--SPAQIQNLADFAEKASTGCLIIP-NFSIGMVLLQQAAVTASQYFDHVEIIELHHNQKADAPSGTAIQT---------------------AELLAEL-----GKTFNSAIVEETEKIPGARGSLIRIHSVRLPGLIAHQEVIFGAPGQIYTLRHDTSDRAC---------------------------------------------------YMPGVLLAIRKVLQLKSLVYGLEKI-L-----------

5kt0A

0.19

0.14

0.73

1.78

dPPAS

--APIPVIVNGAGKMGREVVKAIAQAPDLNLLGAIDSSPEHQGKDAGELAGLSPLEVPITNQLEPMLGYPGVIVDFTHPDSVYDNVRSAIAYGIRVVGTTGL---SPAQIQNLADFAEKASTGCLIIP-NFSIGMVLLQQAAVTASQYFDHVEIIELHHNQKADAPSGTAIQTALGKTFNSAIVEETEKIPGAR-------------------------GSLAGEGIRI--HSVRLPGLIAHQEVIFGAPGQIYTLRHDTSDRAC---------------------------------------------------YMPGVLLAIRKVLQLKSLVYGLEKIL------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.46

Estimated TM-score = 0.54±0.15

Estimated RMSD = 9.9±4.6Å

Download Model 2

C-score=-2.55

Download Model 3

C-score=-2.42

Download Model 4

C-score=-3.88

Download Model 5

C-score=-3.25

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3ijpB	0.724	1.13	0.144	0.743
2	4ywjA	0.679	2.14	0.156	0.740
3	4f3yA	0.671	2.39	0.186	0.743
4	1dihA	0.668	2.68	0.164	0.757
5	3qy9A	0.623	2.05	0.135	0.669
6	5kt0A	0.617	3.03	0.174	0.709
7	1yl5A	0.592	2.64	0.122	0.650
8	4lgvA	0.589	4.74	0.098	0.774
9	2nvwA	0.582	5.10	0.068	0.799
10	5eerA	0.582	2.75	0.105	0.647

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.36	18	1druA	NAD	Rep, Mult	10,13,14,15,36,37,76,77,78,81,99,100,101,126,127,128,129,317
2	0.04	2	3ec7C	NAD	Rep, Mult	13,14,15,35,36,37,38,41,63,76,78,79,81,82,99,100,101,317
3	0.04	2	1yl5A	MG	Rep, Mult	23,24,26,29
4	0.04	2	1arzB	PDC	Rep, Mult	100,127,159,162,167,193,194,317
5	0.02	1	2o4uX	PO4	Rep, Mult	11,13,41
6	0.02	1	1h6dA	NDP	Rep, Mult	86,92,93,94,95,96
7	0.02	1	1arzA	PO4	Rep, Mult	159,162,240,314

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.208	1dihA	0.668	2.68	0.164	0.757	1.3.1.26	NA
2	0.144	1vm6B	0.513	3.14	0.116	0.605	1.3.1.26	NA
3	0.067	2o48X	0.576	4.96	0.085	0.774	1.1.1.179,1.3.1.20	NA
4	0.067	2h63D	0.523	4.78	0.105	0.701	1.3.1.24	NA
5	0.067	3ec7A	0.567	4.61	0.098	0.751	1.1.1.18	NA
6	0.067	3ceaA	0.560	4.91	0.085	0.754	1.1.1.18	13,78,109
7	0.066	2dc1A	0.467	4.61	0.096	0.622	1.4.1.21	127
8	0.066	1gcuA	0.525	4.63	0.102	0.695	1.3.1.24	205
9	0.060	1qkiF	0.579	4.82	0.053	0.768	1.1.1.49	NA
10	0.060	2cvoA	0.557	4.87	0.082	0.746	1.2.1.38	318
11	0.060	2gd1O	0.528	5.06	0.106	0.723	1.2.1.12	13,127,236
12	0.060	3euwD	0.553	4.71	0.113	0.735	1.1.1.18	83,124
13	0.060	1dpgA	0.577	4.96	0.059	0.780	1.1.1.49	NA
14	0.060	2ep5A	0.541	5.23	0.124	0.749	1.2.1.11	NA
15	0.060	1yl5A	0.592	2.64	0.122	0.650	1.3.1.26	NA
16	0.060	2ph5A	0.565	4.82	0.087	0.763	2.5.1.44	13,15
17	0.060	2g17A	0.541	4.96	0.114	0.735	1.2.1.38	13
18	0.060	1h6dA	0.565	4.95	0.076	0.774	1.1.99.28	NA
19	0.060	3ijpB	0.724	1.13	0.144	0.743	1.3.1.26	NA
20	0.060	1k3tA	0.530	5.06	0.070	0.729	1.2.1.12	NA
21	0.060	2ixaA	0.555	5.35	0.084	0.771	3.2.1.49	11,13,78,88
22	0.060	1ydwB	0.546	5.00	0.079	0.749	1.-.-.-	NA
23	0.060	1e5qA	0.568	4.81	0.079	0.760	1.5.1.10	98,318
24	0.060	2glxE	0.551	5.08	0.088	0.751	1.1.1.263	NA
25	0.060	1i33C	0.532	5.01	0.081	0.729	1.2.1.12	NA
26	0.060	1p1jA	0.565	4.69	0.110	0.751	5.5.1.4	13
27	0.060	2o4uX	0.575	4.96	0.088	0.774	1.3.1.20	13

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.25	0.592	2.64	0.12	0.65	1yl5A	GO:0005618 GO:0005737 GO:0005829 GO:0005886 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114 GO:0070402 GO:0070404
1	0.24	0.724	1.13	0.14	0.74	3ijpB	GO:0005737 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114
2	0.21	0.679	2.14	0.16	0.74	4ywjA	GO:0005737 GO:0005829 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114
3	0.20	0.671	2.39	0.19	0.74	4f3yA	GO:0005737 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114
4	0.18	0.668	2.68	0.16	0.76	1dihA	GO:0005737 GO:0005829 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0042802 GO:0050661 GO:0051287 GO:0055114
5	0.17	0.582	2.75	0.10	0.65	5eerA	GO:0005737 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114
6	0.16	0.505	4.32	0.13	0.63	3bioB	GO:0008652 GO:0009085 GO:0009089 GO:0016491 GO:0019877 GO:0047850 GO:0055114
7	0.13	0.511	4.28	0.16	0.65	3wb9A	GO:0000166 GO:0008652 GO:0009085 GO:0009089 GO:0016491 GO:0019877 GO:0047850 GO:0055114
8	0.12	0.594	2.73	0.10	0.67	3qy9B	GO:0005737 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0042802 GO:0050661 GO:0051287 GO:0055114
9	0.08	0.538	5.01	0.13	0.73	3c1aA	GO:0016491 GO:0055114
10	0.08	0.513	3.14	0.12	0.60	1vm6B	GO:0005737 GO:0005829 GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0016726 GO:0019877 GO:0050661 GO:0051287 GO:0055114
11	0.07	0.528	4.24	0.10	0.67	3wybA	GO:0008652 GO:0008839 GO:0009085 GO:0009089 GO:0016491 GO:0019877 GO:0047850 GO:0055114
12	0.07	0.525	4.88	0.10	0.71	4mvjB	GO:0006006 GO:0016491 GO:0016620 GO:0050661 GO:0051287 GO:0055114
13	0.06	0.380	3.62	0.11	0.45	3e8xA	GO:0000166
14	0.06	0.380	6.77	0.03	0.65	4txgA	GO:0004553 GO:0004568 GO:0005576 GO:0005975 GO:0006032 GO:0008152 GO:0016787 GO:0016798 GO:0030246
15	0.06	0.309	7.03	0.05	0.55	3n5mA	GO:0003824 GO:0008483 GO:0016740 GO:0030170
16	0.06	0.309	3.87	0.06	0.39	2gt1A	GO:0008152 GO:0008920 GO:0009244 GO:0016740 GO:0016757
17	0.06	0.263	7.26	0.03	0.47	3ugtC	GO:0000166 GO:0003723 GO:0004812 GO:0004829 GO:0005524 GO:0005737 GO:0005739 GO:0005759 GO:0006412 GO:0006418 GO:0006435 GO:0016874 GO:0070159
18	0.06	0.301	7.04	0.07	0.52	1hfeL	GO:0005506 GO:0008901 GO:0016491 GO:0042597 GO:0046872 GO:0051536 GO:0051539 GO:0055114
19	0.06	0.172	6.08	0.04	0.27	1ojvA	GO:0000139 GO:0001618 GO:0002376 GO:0005576 GO:0005886 GO:0005887 GO:0006888 GO:0006958 GO:0007204 GO:0008289 GO:0009986 GO:0016020 GO:0016032 GO:0030133 GO:0030449 GO:0031225 GO:0031664 GO:0033116 GO:0035743 GO:0045087 GO:0045121 GO:0045730 GO:0045916 GO:0046718 GO:0070062 GO:2000516 GO:2000563

Consensus prediction of GO terms

Molecular Function	GO:0050661	GO:0051287	GO:0016726	GO:0008839	GO:0005515
GO-Score	0.70	0.70	0.70	0.70	0.36
Biological Processes	GO:0009089	GO:0055114	GO:0019877
GO-Score	0.70	0.70	0.70
Cellular Component	GO:0005829	GO:0030312	GO:0016020
GO-Score	0.51	0.51	0.38

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.