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I-TASSER results for job id Rv1057

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)


 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)


  Ligand binding sites

Rank C-score Cluster
size
PDB
Hit
Lig
Name
Download
Complex
Ligand Binding Site Residues
10.16 23 5sxmA III Rep, Mult 38,39,40,81,82,83,102,125,127,128,143,172,173,191,296,334,350
20.07 11 2xu7A III Rep, Mult 35,36,40,57,83,84,125,127,175,219,293,295,332,350,352
30.06 9 2ce9A III Rep, Mult 81,83,125,127,146,173,175,247,263,295,334,350,377
40.04 7 2h6nA III Rep, Mult 38,39,40,83,102,127,146,267,268,291,293,311,333,334,335,337,393
50.03 4 3odtA CA Rep, Mult 38,350,352
60.03 4 3iiwA III Rep, Mult 40,83,263,294,295,296,334
70.03 4 4a0bD NUC Rep, Mult 80,102,122,146,147,171,173,217,263,293,311
80.03 6 4a0bB NUC Rep, Mult 37,78,79,102,103,123,125,173,193,217,267,292
90.03 5 3jzhA III Rep, Mult 40,83,244,245,263,294,295,296,334
100.02 3 3frxC MN Rep, Mult 86,130,131
110.01 1 3mksD C1C Rep, Mult 286,287,289,315,316,317,324,326,327
120.01 1 1kb0A CA Rep, Mult 56,59,61
130.01 1 2xl2A III Rep, Mult 46,89,90,92,96,118,131,133,156
140.01 2 2xl2B III Rep, Mult 181,300,301,302,304,305,326,343,360
150.01 1 3odtA CA Rep, Mult 47,340
160.01 1 2xl3B III Rep, Mult 181,252,253,254,257,283,320
170.01 1 2xl3B III Rep, Mult 89,132,133,134,137,162,181,202
180.01 1 4a09B CA Rep, Mult 176,222,337
190.01 1 1a0rB FAR Rep, Mult 329,332,333,347,349,351,353,355,357
200.01 1 4a09B NUC Rep, Mult 291,311,331,332,352

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit
TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.1503fw0A0.5463.820.1440.6624.3.2.5NA
20.1491rwlA0.5073.950.1300.6262.7.11.1129
30.1091ri6A0.6422.890.1460.7233.1.1.31NA
40.0973dr2A0.5204.000.1170.6493.1.1.17NA
50.0771pjxA0.5254.170.1000.6593.1.8.2NA
60.0672h47H0.6183.380.1140.7251.4.99.463,111,133
70.0672fpcA0.5123.940.1110.6364.3.3.2124,126,170
80.0661vcuB0.5604.020.0710.7003.2.1.18NA
90.0662htrA0.5265.240.0810.7303.2.1.18NA
100.0661cvmA0.5404.070.0680.6743.1.3.842,295
110.0662aepA0.5535.120.0660.7533.2.1.18NA
120.0661a4gA0.5514.670.0510.7303.2.1.18NA
130.0661v04A0.5194.150.1030.6543.1.1.2,3.1.8.1NA
140.0661v0zA0.5505.170.0500.7483.2.1.18NA
150.0662uvkB0.5154.410.0710.6625.1.3.-85,89,130
160.0601ingA0.5535.120.0630.7533.2.1.18NA
170.0603elqB0.5535.100.0550.7532.8.2.22NA
180.0603fsnB0.5784.710.0570.7585.2.1.7NA
190.0601nn2A0.5555.070.0660.7513.2.1.18164
200.0601lrwA0.6604.430.0720.8371.1.99.8NA
210.0601aomB0.6594.250.0830.8321.7.99.1,1.7.2.1NA
220.0601yr2A0.5944.330.0860.7563.4.21.26NA
230.0601jofA0.6273.330.0990.7285.5.1.5147
240.0601k32A0.5754.700.0600.7483.4.21.-NA
250.0602ht8A0.5255.200.0810.7283.2.1.18NA
260.0601madH0.5933.820.0550.7231.4.99.385,109
270.0603c75J0.5993.820.1190.7301.4.99.390,108,131,133
280.0602madH0.5963.860.0900.7301.4.99.3110,133
290.0601kv9A0.7084.330.0860.9031.1.99.-NA
300.0602f10A0.5454.210.0830.6903.2.1.18NA
310.0601qksB0.6594.240.0830.8321.7.2.180,82,102
320.0602gc7A0.5973.840.1090.7301.4.99.3108,110,131,133
330.0601lrwC0.6594.380.0660.8351.1.99.8NA
340.0601yiqA0.6754.370.0670.8551.1.99.-NA

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.290.6112.540.110.674yvdA GO:0000398 GO:0000974 GO:0005634 GO:0005654 GO:0005662 GO:0005681 GO:0005730 GO:0006397 GO:0008380 GO:0016607 GO:0031965 GO:0034504 GO:0071011 GO:0071013 GO:0080008 GO:1900087
10.260.7043.300.150.792ymuA GO:0016020 GO:0016021
20.260.6762.040.110.733jb9L GO:0005634 GO:0005681 GO:0005682 GO:0006397 GO:0008380 GO:0045292
30.240.6872.140.130.742pbiD GO:0001750 GO:0001917 GO:0004871 GO:0005096 GO:0005634 GO:0005829 GO:0005886 GO:0007165 GO:0007186 GO:0016020 GO:0031682 GO:0043209 GO:0043547 GO:0051087 GO:1901386
40.240.6232.950.130.695a2qg GO:0001649 GO:0001891 GO:0001934 GO:0005080 GO:0005102 GO:0005634 GO:0005737 GO:0005739 GO:0005829 GO:0005886 GO:0005913 GO:0006417 GO:0006915 GO:0006919 GO:0007049 GO:0007275 GO:0007369 GO:0008200 GO:0008656 GO:0010629 GO:0010803 GO:0015935 GO:0016020 GO:0016032 GO:0017148 GO:0019899 GO:0019903 GO:0030178 GO:0030292 GO:0030308 GO:0030335 GO:0030425 GO:0030496 GO:0030822 GO:0030971 GO:0032436 GO:0032464 GO:0032880 GO:0032947 GO:0033137 GO:0035591 GO:0040008 GO:0042169 GO:0042803 GO:0042995 GO:0042998 GO:0043005 GO:0043025 GO:0043065 GO:0043204 GO:0043547 GO:0044297 GO:0044822 GO:0048471 GO:0048511 GO:0050765 GO:0051302 GO:0051343 GO:0051726 GO:0051898 GO:0051901 GO:0061099 GO:0070062 GO:0071333 GO:0071363 GO:0090003 GO:0098609 GO:0098641 GO:1900102 GO:1903208 GO:1990630 GO:2000114 GO:2000304 GO:2000543 GO:2001244
50.230.6423.650.100.741pguB GO:0003779 GO:0005737 GO:0005856 GO:0005884 GO:0006970 GO:0030042 GO:0030479 GO:0032466 GO:0051016
60.230.7213.290.120.834wjsA GO:0005634 GO:0005730 GO:0042254
70.230.6933.550.090.813v7dB GO:0000082 GO:0000086 GO:0004842 GO:0005634 GO:0007049 GO:0007067 GO:0007126 GO:0016363 GO:0016567 GO:0019005 GO:0030435 GO:0031146 GO:0042787 GO:0043130 GO:0043224 GO:0050815 GO:0051301 GO:0061630
80.220.6882.320.100.752ybaB GO:0000122 GO:0000281 GO:0003682 GO:0005634 GO:0005667 GO:0005700 GO:0006281 GO:0006334 GO:0006335 GO:0006342 GO:0006351 GO:0006355 GO:0007307 GO:0007346 GO:0007379 GO:0007517 GO:0008284 GO:0016568 GO:0016571 GO:0016573 GO:0016581 GO:0016584 GO:0016589 GO:0016590 GO:0031491 GO:0031497 GO:0031523 GO:0033186 GO:0035035 GO:0035097 GO:0035098 GO:0042054 GO:0042393 GO:0042766 GO:0042803 GO:0042826 GO:0046974 GO:0046976 GO:0048666 GO:0048812 GO:0048813 GO:0051567 GO:0061085 GO:0070615 GO:0070734 GO:0070822
90.220.6762.750.080.763acpA GO:0000502 GO:0005634 GO:0005737 GO:0005829 GO:0006511 GO:0070682
100.220.6772.320.170.743ow8C GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0016055 GO:0016593 GO:0032968 GO:0035327 GO:0045638 GO:0045944 GO:0051571 GO:0055087 GO:0080182 GO:2001162
110.210.6792.290.090.744j87A GO:0000139 GO:0005198 GO:0005737 GO:0005794 GO:0006810 GO:0006886 GO:0006888 GO:0006890 GO:0006891 GO:0015031 GO:0016020 GO:0016192 GO:0030117 GO:0030126 GO:0030137
120.200.6872.340.100.753gfcA GO:0000790 GO:0000978 GO:0000980 GO:0004407 GO:0005634 GO:0005654 GO:0006260 GO:0006335 GO:0006336 GO:0006338 GO:0006351 GO:0006355 GO:0007049 GO:0008094 GO:0008285 GO:0016568 GO:0016575 GO:0016580 GO:0016581 GO:0016589 GO:0031492 GO:0031497 GO:0033186 GO:0034080 GO:0035098 GO:0042393 GO:0042826 GO:0043044 GO:0043234 GO:0045814 GO:0051726 GO:1901796
130.200.6882.500.120.764lg8A GO:0000209 GO:0000244 GO:0000245 GO:0000398 GO:0000974 GO:0001833 GO:0004842 GO:0005634 GO:0005654 GO:0005662 GO:0005681 GO:0005737 GO:0005811 GO:0005819 GO:0005856 GO:0006281 GO:0006283 GO:0006303 GO:0006397 GO:0006974 GO:0008380 GO:0008610 GO:0010498 GO:0016020 GO:0016567 GO:0016607 GO:0016874 GO:0034450 GO:0034613 GO:0035861 GO:0042802 GO:0045665 GO:0048026 GO:0048711 GO:0061630 GO:0070534 GO:0071013 GO:0072422
140.180.6863.230.100.794lg9A GO:0000118 GO:0000122 GO:0002021 GO:0003677 GO:0003714 GO:0005634 GO:0005654 GO:0005876 GO:0006351 GO:0006355 GO:0008013 GO:0010468 GO:0016042 GO:0016568 GO:0016575 GO:0017053 GO:0030814 GO:0035264 GO:0042393 GO:0043161 GO:0044212 GO:0044255 GO:0045892 GO:0045893 GO:0045944 GO:0047485 GO:0050872 GO:0060070 GO:0060612 GO:0060613 GO:0090207
150.160.6762.300.120.741b9xA GO:0001750 GO:0003924 GO:0004871 GO:0005622 GO:0005765 GO:0005834 GO:0007165 GO:0007186 GO:0007191 GO:0007200 GO:0008283 GO:0016020 GO:0016056 GO:0022400 GO:0032403 GO:0043209 GO:0050909 GO:0051020 GO:0060041 GO:0070062 GO:0071380 GO:0071870 GO:0097381 GO:1903561
160.160.6842.710.080.763i2nA GO:0006915 GO:0043130
170.150.6912.250.120.753jcrL GO:0000375 GO:0000398 GO:0005634 GO:0005654 GO:0005681 GO:0006396 GO:0006397 GO:0008380 GO:0015030 GO:0016607 GO:0017070 GO:0030621 GO:0046540 GO:0071001 GO:0097525
180.140.6892.220.110.743fm0A GO:0006357 GO:0007059 GO:0008284 GO:0016226 GO:0071817 GO:0097361
190.140.6922.440.110.754v6wAg GO:0000398 GO:0005080 GO:0005737 GO:0005776 GO:0005829 GO:0005875 GO:0007626 GO:0009267 GO:0016243 GO:0018991 GO:0035220 GO:0042335 GO:0044829 GO:0045725 GO:0046716 GO:0048477 GO:0071011 GO:0071013 GO:0075522
200.140.6842.470.110.743jb9K GO:0000974 GO:0005634 GO:0005662 GO:0005681 GO:0006397 GO:0008380 GO:0045292 GO:0071011 GO:0071013 GO:0080008
210.140.6822.430.110.745it9g GO:0000747 GO:0001403 GO:0001965 GO:0004871 GO:0005080 GO:0005092 GO:0005737 GO:0007186 GO:0010255 GO:0017148 GO:0022627 GO:0031139 GO:0031954 GO:0032995 GO:0034613 GO:0035556 GO:0043022 GO:0050790 GO:0060733
220.140.5942.900.130.664g56D GO:0005634 GO:0005737 GO:0005829 GO:0034709 GO:0035097
230.140.5872.870.090.653odtA GO:0005634 GO:0005737 GO:0006303 GO:0006511 GO:0010992 GO:0043130
240.130.6772.450.120.744v6iAa GO:0001403 GO:0001965 GO:0004871 GO:0005092 GO:0005737 GO:0007186 GO:0010255 GO:0017148 GO:0022627 GO:0050790 GO:2001125
250.130.6692.350.150.735igoC GO:0000152 GO:0004842 GO:0005634 GO:0005737 GO:0006281 GO:0008270 GO:0009585 GO:0009640 GO:0009641 GO:0009647 GO:0009649 GO:0010017 GO:0010119 GO:0016567 GO:0016604 GO:0016874 GO:0032436 GO:0042802 GO:0046283 GO:0046872 GO:0048573 GO:0061630 GO:0080008
260.130.6682.290.110.732hesX GO:0002098 GO:0005634 GO:0005737 GO:0005829 GO:0016226 GO:0044281 GO:0097361
270.130.6842.390.110.742h9lA GO:0000123 GO:0001501 GO:0005622 GO:0005634 GO:0005654 GO:0005671 GO:0006351 GO:0006355 GO:0016568 GO:0018024 GO:0031175 GO:0035064 GO:0035097 GO:0035948 GO:0042800 GO:0043966 GO:0043981 GO:0043982 GO:0043984 GO:0043995 GO:0043996 GO:0044666 GO:0046972 GO:0048188 GO:0051568 GO:0071339
280.130.6852.450.120.754btsAR GO:0005840
290.120.6163.050.100.695hqgA GO:0000139 GO:0004842 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005925 GO:0008270 GO:0010212 GO:0016567 GO:0016607 GO:0016874 GO:0032436 GO:0046872 GO:0061630
300.120.6152.710.100.683rfhA GO:0001403 GO:0001965 GO:0004871 GO:0005092 GO:0005737 GO:0007186 GO:0010255 GO:0017148 GO:0022627 GO:0050790 GO:2001125
310.120.6233.090.100.691erjC GO:0000122 GO:0000123 GO:0000433 GO:0001191 GO:0001198 GO:0005634 GO:0006351 GO:0006355 GO:0007070 GO:0008023 GO:0016584 GO:0017053 GO:0033588 GO:0035955 GO:0036033 GO:0042393 GO:0042826 GO:0043486 GO:0080025 GO:2000217 GO:2000531 GO:2001020
320.120.6842.560.120.763zwlD GO:0001731 GO:0002183 GO:0002188 GO:0003743 GO:0005737 GO:0005852 GO:0006412 GO:0006413 GO:0006446 GO:0016282 GO:0033290 GO:0043614
330.110.6493.010.100.734l9oA GO:0005634 GO:0005643 GO:0005783 GO:0005789 GO:0006810 GO:0012507 GO:0015031 GO:0016020 GO:0016192 GO:0031410 GO:0051028
340.110.6772.940.130.765hynB GO:0000122 GO:0001739 GO:0003682 GO:0005634 GO:0005654 GO:0005694 GO:0005730 GO:0006349 GO:0006351 GO:0006355 GO:0016568 GO:0016571 GO:0021510 GO:0035098 GO:0042054 GO:0042802 GO:0045120 GO:0045814 GO:0045892 GO:0061087
350.110.6832.720.100.763mmyC GO:0000972 GO:0003723 GO:0005634 GO:0005635 GO:0005643 GO:0005730 GO:0005737 GO:0006406 GO:0006409 GO:0006606 GO:0007077 GO:0008017 GO:0010827 GO:0016032 GO:0016925 GO:0019083 GO:0031047 GO:0043130 GO:0071407 GO:0075733 GO:1900034
360.110.6682.590.140.742ce8A GO:0000122 GO:0001106 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0007165 GO:0007275 GO:0008134 GO:0009887 GO:0010628 GO:0016055 GO:0030178 GO:0042802 GO:0043124 GO:0045892 GO:1904837 GO:2000811
370.110.5584.810.110.745em2A GO:0000463 GO:0000466 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030687 GO:0042254 GO:0042273 GO:0043021
380.110.6862.780.120.764a11B GO:0000109 GO:0000209 GO:0003678 GO:0004842 GO:0005634 GO:0005654 GO:0006281 GO:0006283 GO:0006289 GO:0006974 GO:0006979 GO:0008094 GO:0009411 GO:0010165 GO:0016363 GO:0016567 GO:0031464 GO:0032403 GO:0043161 GO:0043234 GO:0045739 GO:0051865
390.110.6452.700.110.715flcD GO:0005654 GO:0005737 GO:0005829 GO:0007050 GO:0016236 GO:0030838 GO:0031295 GO:0031931 GO:0031932 GO:0032008 GO:0032956 GO:0043087 GO:0048015 GO:0050731 GO:1900034
400.110.6822.420.080.754pswB GO:0000123 GO:0000781 GO:0004402 GO:0005634 GO:0005737 GO:0006333 GO:0006348 GO:0016568 GO:0016573 GO:0042393
410.110.6722.680.110.751s4uX GO:0000228 GO:0005634 GO:0005694 GO:0005737 GO:0006461 GO:0007131 GO:0034427 GO:0051321 GO:0051607 GO:0055087 GO:0065004 GO:0070478 GO:0070481
420.110.6852.490.120.754xyhA GO:0000070 GO:0000778 GO:0000790 GO:0005634 GO:0005829 GO:0051382 GO:0061638 GO:0061641 GO:0070317 GO:0098654
430.100.7152.280.120.771vyhC GO:0000132 GO:0000226 GO:0000235 GO:0000776 GO:0001667 GO:0001675 GO:0001764 GO:0001961 GO:0005634 GO:0005635 GO:0005737 GO:0005813 GO:0005815 GO:0005819 GO:0005829 GO:0005856 GO:0005871 GO:0005874 GO:0005875 GO:0005938 GO:0006629 GO:0006810 GO:0007017 GO:0007049 GO:0007067 GO:0007097 GO:0007268 GO:0007275 GO:0007399 GO:0007405 GO:0007420 GO:0007611 GO:0008017 GO:0008090 GO:0008344 GO:0009306 GO:0010977 GO:0015630 GO:0016020 GO:0016042 GO:0016477 GO:0017145 GO:0019226 GO:0021540 GO:0021766 GO:0021819 GO:0021895 GO:0021987 GO:0030036 GO:0030154 GO:0030424 GO:0030426 GO:0031023 GO:0031252 GO:0031512 GO:0031965 GO:0031982 GO:0032403 GO:0032420 GO:0036035 GO:0040019 GO:0042249 GO:0042803 GO:0043005 GO:0043025 GO:0043087 GO:0043622 GO:0045502 GO:0045505 GO:0045773 GO:0045931 GO:0046329 GO:0047496 GO:0048471 GO:0048854 GO:0050885 GO:0051081 GO:0051130 GO:0051219 GO:0051301 GO:0051660 GO:0051661 GO:0060117 GO:0061003 GO:0070062 GO:0070507 GO:0090102 GO:0090176 GO:1904115 GO:2000574
440.100.6053.380.110.724v16A GO:0000407 GO:0005773 GO:0005774 GO:0005794 GO:0006810 GO:0006914 GO:0015031 GO:0016020 GO:0030659 GO:0031410
450.100.5644.680.110.744u7aA GO:0000463 GO:0000466 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030687 GO:0042254 GO:0042273 GO:0043021 GO:0070180 GO:0070545
460.100.6732.940.090.754jxmA GO:0003723 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030529 GO:0031428 GO:0032040 GO:0034511 GO:0044822
470.100.6303.440.090.713cfvB GO:0000122 GO:0003723 GO:0004407 GO:0005634 GO:0005654 GO:0006260 GO:0006351 GO:0006355 GO:0007275 GO:0008283 GO:0016568 GO:0016575 GO:0016581 GO:0030308 GO:0034080 GO:0035098 GO:0045814 GO:0045892 GO:0048545 GO:0070370 GO:1901796
480.100.5542.390.110.613eweA GO:0005634 GO:0005643 GO:0005773 GO:0005774 GO:0006810 GO:0006913 GO:0015031 GO:0016020 GO:0017056 GO:0031080 GO:0031965 GO:0035859 GO:0051028 GO:0097042 GO:1904263
490.100.6642.870.090.754a0aB GO:0003677 GO:0003684 GO:0005634 GO:0006281 GO:0006974 GO:0016567 GO:0080008
500.100.6092.580.120.683mzkA GO:0000139 GO:0005198 GO:0005634 GO:0005643 GO:0005773 GO:0005774 GO:0005783 GO:0005789 GO:0006810 GO:0012507 GO:0015031 GO:0016020 GO:0016192 GO:0030127 GO:0030433 GO:0031080 GO:0031081 GO:0031410 GO:0035859 GO:0042802 GO:0043547 GO:0045893 GO:0051028 GO:0090114 GO:1904263
510.100.6912.570.120.764v3pSa GO:0007165
520.100.6373.580.100.754ci8A GO:0000226 GO:0002244 GO:0005509 GO:0005737 GO:0005829 GO:0005856 GO:0005874 GO:0005875 GO:0007052 GO:0007405 GO:0007420 GO:0008017 GO:0015631 GO:0048471 GO:0097431 GO:1990023
530.100.6612.680.100.741u2vC GO:0003779 GO:0005200 GO:0005737 GO:0005829 GO:0005856 GO:0005885 GO:0005925 GO:0015629 GO:0030833 GO:0034314 GO:0051015 GO:0070062
540.100.6702.520.110.744ui9R GO:0005634 GO:0005654 GO:0005680 GO:0005737 GO:0005829 GO:0006281 GO:0006974 GO:0007049 GO:0007067 GO:0008284 GO:0010997 GO:0016567 GO:0031145 GO:0031572 GO:0031965 GO:0040020 GO:0042787 GO:0045732 GO:0051301 GO:0051436 GO:0051437 GO:0051439 GO:0070306 GO:0070979 GO:0090344 GO:0097027 GO:1904668
550.100.6863.510.150.814v7fq GO:0000027 GO:0005634 GO:0005730 GO:0042254
560.100.6052.870.130.673jcrD GO:0000375 GO:0000398 GO:0005634 GO:0005654 GO:0005681 GO:0005682 GO:0005732 GO:0005737 GO:0006396 GO:0006397 GO:0008380 GO:0044822 GO:0071011 GO:0071013
570.100.5912.480.130.655a9q6 GO:0000139 GO:0000776 GO:0002474 GO:0005634 GO:0005635 GO:0005643 GO:0005654 GO:0005783 GO:0005789 GO:0005829 GO:0006810 GO:0006886 GO:0007062 GO:0012507 GO:0015031 GO:0016020 GO:0016192 GO:0019886 GO:0031080 GO:0031410 GO:0032008 GO:0043231 GO:0048208 GO:0051028 GO:0061700 GO:0070062
580.100.6102.660.120.683f3fA GO:0005634 GO:0005643 GO:0005773 GO:0005774 GO:0006810 GO:0006913 GO:0015031 GO:0016020 GO:0017056 GO:0031080 GO:0031965 GO:0035859 GO:0051028 GO:0097042 GO:1904263
590.100.6842.960.110.774bujC GO:0000228 GO:0005634 GO:0005694 GO:0005737 GO:0006461 GO:0007131 GO:0034427 GO:0051321 GO:0051607 GO:0055087 GO:0065004 GO:0070478 GO:0070481
600.100.6882.340.100.754pc0B GO:0000790 GO:0000978 GO:0000980 GO:0004407 GO:0005634 GO:0005654 GO:0006260 GO:0006335 GO:0006336 GO:0006338 GO:0006351 GO:0006355 GO:0007049 GO:0008094 GO:0008285 GO:0016568 GO:0016575 GO:0016580 GO:0016581 GO:0016589 GO:0031492 GO:0031497 GO:0033186 GO:0034080 GO:0035098 GO:0042393 GO:0042826 GO:0043044 GO:0043234 GO:0045814 GO:0051726 GO:1901796
610.090.6463.390.100.762aq5A GO:0001772 GO:0001845 GO:0001891 GO:0003779 GO:0003785 GO:0005737 GO:0005769 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005911 GO:0005938 GO:0006816 GO:0006909 GO:0007015 GO:0008022 GO:0008064 GO:0008092 GO:0008360 GO:0015629 GO:0016020 GO:0016477 GO:0030027 GO:0030036 GO:0030335 GO:0030424 GO:0030595 GO:0030670 GO:0030833 GO:0030864 GO:0031252 GO:0031339 GO:0031410 GO:0031589 GO:0032036 GO:0032796 GO:0032956 GO:0034097 GO:0038180 GO:0042102 GO:0042802 GO:0042803 GO:0043029 GO:0043234 GO:0043320 GO:0043524 GO:0043548 GO:0044822 GO:0045335 GO:0048873 GO:0050870 GO:0050918 GO:0051015 GO:0051126 GO:0051279 GO:0061502 GO:0070062 GO:0071353
620.090.6603.240.070.754j0xB GO:0000154 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030515 GO:0030529 GO:0031167 GO:0031428 GO:0032040 GO:0042254
630.090.6083.280.110.724av8A GO:0000407 GO:0005773 GO:0005774 GO:0005794 GO:0006810 GO:0006914 GO:0015031 GO:0016020 GO:0030659 GO:0031410
640.090.6523.200.210.741l0qA GO:0016020 GO:0016021
650.090.6752.490.120.744aezA GO:0000070 GO:0005634 GO:0007049 GO:0007067 GO:0010997 GO:0032153 GO:0033597 GO:0034613 GO:0044732 GO:0051301 GO:0072686 GO:0097027 GO:1904668
660.080.6132.640.130.685a9q7 GO:0000775 GO:0000776 GO:0000777 GO:0002534 GO:0005634 GO:0005635 GO:0005643 GO:0005694 GO:0005829 GO:0006406 GO:0006409 GO:0006810 GO:0006999 GO:0007049 GO:0007059 GO:0007062 GO:0007067 GO:0007077 GO:0007080 GO:0010827 GO:0015031 GO:0016032 GO:0016925 GO:0019083 GO:0031047 GO:0031080 GO:0032008 GO:0034198 GO:0034629 GO:0050830 GO:0051028 GO:0051301 GO:0051315 GO:0061700 GO:0075733 GO:1900034 GO:1904263
670.080.6603.010.090.754e54B GO:0000209 GO:0000715 GO:0000717 GO:0003677 GO:0003684 GO:0004842 GO:0005634 GO:0005654 GO:0006281 GO:0006289 GO:0006290 GO:0006293 GO:0006294 GO:0006295 GO:0006296 GO:0006974 GO:0009411 GO:0016567 GO:0030054 GO:0031465 GO:0033683 GO:0035518 GO:0043234 GO:0051865 GO:0070911 GO:0070914 GO:0080008
680.080.6822.360.140.743jcmB GO:0000398 GO:0005634 GO:0005681 GO:0006397 GO:0008380 GO:0017070 GO:0030621 GO:0034247 GO:0046540
690.080.6084.360.070.771r5mA GO:0003714 GO:0005634 GO:0006355 GO:0006357 GO:0016568 GO:0016575 GO:0031939 GO:0032874 GO:0034967 GO:0045835 GO:1903507
700.070.6722.370.100.735g04R GO:0000922 GO:0005634 GO:0005654 GO:0005680 GO:0005737 GO:0005813 GO:0005815 GO:0005819 GO:0005829 GO:0005856 GO:0007049 GO:0007062 GO:0007067 GO:0007399 GO:0008022 GO:0008284 GO:0010997 GO:0016567 GO:0019899 GO:0030154 GO:0031145 GO:0031915 GO:0040020 GO:0042787 GO:0042826 GO:0043161 GO:0043234 GO:0048471 GO:0050773 GO:0051301 GO:0051436 GO:0051437 GO:0051439 GO:0090129 GO:0097027 GO:1904668
710.070.6362.550.080.715a9q2 GO:0000775 GO:0000776 GO:0000777 GO:0005634 GO:0005635 GO:0005643 GO:0005654 GO:0005694 GO:0005829 GO:0006406 GO:0006409 GO:0006810 GO:0007049 GO:0007059 GO:0007062 GO:0007067 GO:0007077 GO:0010827 GO:0015031 GO:0016032 GO:0016925 GO:0019083 GO:0031047 GO:0031080 GO:0051028 GO:0051301 GO:0075733 GO:1900034
720.070.7123.270.140.825fl8q GO:0000027 GO:0005634 GO:0005730 GO:0042254
730.070.7093.450.140.833jctx GO:0000027 GO:0005634 GO:0005730 GO:0042254
740.070.6203.600.100.711p22A GO:0000086 GO:0000209 GO:0002223 GO:0004842 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006470 GO:0006511 GO:0007165 GO:0008013 GO:0016032 GO:0016055 GO:0016567 GO:0016874 GO:0019005 GO:0030163 GO:0031146 GO:0031648 GO:0033598 GO:0038061 GO:0038095 GO:0042752 GO:0042753 GO:0043122 GO:0043161 GO:0043433 GO:0045309 GO:0045862 GO:0045879 GO:0045892 GO:0045893 GO:0046983 GO:0048511 GO:0050852 GO:0051403 GO:0051437 GO:0051726 GO:0060444 GO:0060828 GO:0061136 GO:0061630 GO:0071407
750.070.6712.550.090.745a31R GO:0005634 GO:0005680 GO:0005737 GO:0007049 GO:0007067 GO:0010697 GO:0010997 GO:0030332 GO:0045842 GO:0051301 GO:0097027 GO:1904668 GO:2000060 GO:2000600
760.070.6752.430.100.745cxbA GO:0000463 GO:0000466 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030687 GO:0042254 GO:0042273 GO:0043021
770.070.5273.660.080.631q7fB GO:0005622 GO:0005737 GO:0006417 GO:0006909 GO:0007400 GO:0007402 GO:0007405 GO:0007406 GO:0007411 GO:0007419 GO:0007420 GO:0008270 GO:0008285 GO:0008356 GO:0008582 GO:0009303 GO:0017148 GO:0022008 GO:0030182 GO:0030371 GO:0035282 GO:0043025 GO:0045179 GO:0045180 GO:0045182 GO:0046872 GO:0048477 GO:0050767 GO:0051726 GO:0055060 GO:1900242
780.070.6852.800.070.765cvlA GO:0000724 GO:0005634 GO:0005737 GO:0005764 GO:0005768 GO:0005770 GO:0006974 GO:0007283 GO:0007338 GO:0008584 GO:0016032 GO:0016579 GO:0035264 GO:0043588 GO:0048568 GO:0048705 GO:0048872 GO:0050679 GO:0072520 GO:1902525
790.070.5484.490.110.703dasA GO:0003824 GO:0005975 GO:0016901 GO:0046872 GO:0048038 GO:0055114
800.070.6164.440.120.782ovqB GO:0000209 GO:0001944 GO:0004842 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006974 GO:0007062 GO:0010868 GO:0010883 GO:0016032 GO:0016567 GO:0019005 GO:0030332 GO:0030674 GO:0031146 GO:0031398 GO:0031625 GO:0032876 GO:0032880 GO:0034644 GO:0042802 GO:0043234 GO:0045741 GO:0045746 GO:0050816 GO:0050821 GO:0051443 GO:0055088 GO:0070374 GO:0097027 GO:1901800 GO:1902806 GO:1903146 GO:1903378 GO:1903955 GO:1990452 GO:2000060 GO:2000346 GO:2000639


Consensus prediction of GO terms
 
Molecular Function GO:0030695 GO:0045296 GO:0043028 GO:0016248 GO:0060090 GO:0005198 GO:0098632 GO:0005102 GO:0019904 GO:0016505 GO:0046983 GO:1990782 GO:0003723 GO:0004860 GO:0042802 GO:0019902
GO-Score 0.49 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47
Biological Processes GO:0000377 GO:1901992 GO:2000045 GO:1902808 GO:0033365 GO:1901385 GO:1901020 GO:2001258 GO:0006397 GO:0033135 GO:0030816 GO:0030807 GO:0032462 GO:1903206 GO:2000113 GO:0090154 GO:0070848 GO:1901800 GO:0001959 GO:2001242 GO:0007155 GO:0001558 GO:1903204 GO:0050732 GO:0006417 GO:0033209 GO:0061097 GO:0042996 GO:0043280 GO:0032461 GO:0030820 GO:0009749 GO:1903573 GO:0045806 GO:0032434 GO:0040019 GO:0051900 GO:0034250 GO:2000147 GO:0042327 GO:1904181 GO:0033123 GO:0050764 GO:0034249 GO:0010470 GO:0051896 GO:0030154 GO:1902533 GO:0030334 GO:0001503 GO:1903207 GO:0044764 GO:0031401 GO:2000303 GO:0006469 GO:0051301 GO:0030111 GO:1900101 GO:0051342 GO:0045926 GO:0071331 GO:1902532 GO:0032878 GO:0001678 GO:0044403 GO:0090004 GO:2001235 GO:0051222 GO:0030010 GO:0043547
GO-Score 0.59 0.59 0.59 0.59 0.59 0.49 0.49 0.49 0.48 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.42
Cellular Component GO:0005635 GO:0031090 GO:0043601 GO:0031461 GO:0016604 GO:0097525 GO:0031513 GO:0005681 GO:0044297 GO:0044391 GO:0005912 GO:0005911 GO:0036477 GO:1903561 GO:0031988 GO:0044459 GO:0005829 GO:0031224
GO-Score 0.59 0.59 0.59 0.59 0.59 0.53 0.49 0.48 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.42 0.42

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]



Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.