I-TASSER results

Input Sequence in FASTA format

>protein (174 residues)
MKVQARVGWNRRQLSAVGGRGQQLFANAPGHIPSTSHRRGTGDINRKIDESLAGAARPQA
NANYGATSDPPLTHQPKPGSPTQVGPRSPSPPGLRGLVKQLPEVHQSSLHLDTVASLPSS
RPSPHHTPLALRSRSGHFSPDEIRNRRSRKRSQSHMPPRTPPRGRCLRAPEALA

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MKVQARVGWNRRQLSAVGGRGQQLFANAPGHIPSTSHRRGTGDINRKIDESLAGAARPQANANYGATSDPPLTHQPKPGSPTQVGPRSPSPPGLRGLVKQLPEVHQSSLHLDTVASLPSSRPSPHHTPLALRSRSGHFSPDEIRNRRSRKRSQSHMPPRTPPRGRCLRAPEALA
Prediction	CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	976555555456666647777644578999999988878888888765444467777777777889999999899999999888999999997545678998655567888644357889999988888767788899956544444444555689999999887667874459
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MKVQARVGWNRRQLSAVGGRGQQLFANAPGHIPSTSHRRGTGDINRKIDESLAGAARPQANANYGATSDPPLTHQPKPGSPTQVGPRSPSPPGLRGLVKQLPEVHQSSLHLDTVASLPSSRPSPHHTPLALRSRSGHFSPDEIRNRRSRKRSQSHMPPRTPPRGRCLRAPEALA
Prediction	752434332545425534564453245244424635435354544563445254444442435544464442435444443553346464244233235434523554234520140356444453343334545341336405545435435444475444434125236638
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160

                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
MKVQARVGWNRRQLSAVGGRGQQLFANAPGHIPSTSHRRGTGDINRKIDESLAGAARPQANANYGATSDPPLTHQPKPGSPTQVGPRSPSPPGLRGLVKQLPEVHQSSLHLDTVASLPSSRPSPHHTPLALRSRSGHFSPDEIRNRRSRKRSQSHMPPRTPPRGRCLRAPEALA

3jbmA

0.14

0.13

0.93

1.05

MUSTER

LSGMSRISQAVLPAGT-GTDGYVVVDATPDLLPRLGHA--ARIFQRYAVETLEFEIQPMCPANTGGGYVAGFLPDPTDNDHTFDALQATR--GAVVAKWWESRTVRPQYTRTLLWTSSGKEQR-LTSPGRLILLCVGNNTDVVN-------VSVLCRWSVRLSVPSLETPEETT

3jbmA

0.11

0.10

0.94

1.17

dPPAS

LSGMSRIS------QAVLPAGTGTDGYVVVDATIVPDLLPRLGHAARIFQRYAVETLEFEIQPMCPANTGGGYVAGFLPDPTDNDHTFDALQATRGAVVAKWWESRTVRPQYTRTLLWTSSGKEQRLTSPGRLILLCVGNNTDV-----VNVSVLCRWSVRLSVPSLETPEETT

1r5sA

0.27

0.18

0.69

0.84

wdPPAS

-----------------------------GPLGSPSKDCGSP---------------KYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS--SCRNYNKQASEQNWANYSAETISNSHAQPDFPDDNQNAKKVAAGHLQPLAIVDQRPSSRASSRASSR--PR------PDDLE

1zlgA

0.16

0.15

0.94

1.17

wMUSTER

VTVQPIRP------KSHSKAEAVFFTTPPCSALKGKSHKPIGCLGEAGHVLSKVLAKPENLSASFIVQDVNITAKANLYQPAEVTTESRQNSLPNSIISQSQILPSDHYVLTEVQVLTPGGEGPA-TIKTFRTPEL--PPSSAHRSHLKHRHPHHYKPSPERYGK--PIPNPLL

3jbmA

0.17

0.14

0.86

0.83

wPPAS

LSGMSRIS----VLPAGTGTDGYVVVDAT--VPDLPRLGHAARIFQRYAETLEFEIQPMCPANTGGLPDPT-DNDHTFDALQATRGAVVAKW--ESRTVRPQ--YTRTLLWTSSGKEQR---SPGRLILLCVGNNTDVVNVSVLCRWS---VRLSVPS--------LETPEETT

1mv3A

0.08

0.07

0.83

1.49

dPPAS2

-------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGT--QPAAGAQEPGETAASEAASSS--LPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV

3jbmA

0.17

0.16

0.89

1.13

PPAS

LSGMSRISQAVLPAGT-GTDGYVVVDATPDLLPRLGHA--ARIFQRYAVETLEFEIQPMCPANTGGGYVAGFLPDPTDNDHTFDALQA-----TRGAVVAKWRTVRPQYTRTLLWTSSGKEQSPGRLILLCVGNNTDVVNVSVLCRWS---VRLSVPS--------LETPEETT

2b3bA1

0.15

0.13

0.90

0.72

Env-PPAS

MKLEIFSWWEGPALEAL----IRLYKQKPGVNATVTGGAGVNARAVLKTRMLGGDPPDTFQVHAGMELIGTWV------VANRMEDLSALFRQEGWLQAFPKGLIDLISYKGGIWSVPVNI----SDSFGL--PKGAKNRQNAINWLRLVGSKEGQDTSNPLKGSIARL-DSDP

3gv2A

0.13

0.99

0.95

MUSTER

PIVQNLQG--QMVHQAISPRTLNAWVKVVEEKAFSPEIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKLNKIVRMYSPTSILDIRQGPKEPRDYVDRFYKTLRAEQASQEVK

1mv3A

0.08

0.06

0.83

1.02

dPPAS

-------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP----ATVNGTVEGGSGAGRLDLPPGFMFKV

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.49

Estimated TM-score = 0.33±0.11

Estimated RMSD = 13.2±4.1Å

Download Model 2

C-score=-3.24

Download Model 3

C-score=-3.40

Download Model 4

C-score=-3.75

Download Model 5

C-score=-4.24

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1bmv2	0.645	3.66	0.038	0.897
2	2ztnA	0.607	4.13	0.089	0.891
3	2bfuL	0.600	4.09	0.057	0.902
4	5ewnA	0.593	4.03	0.076	0.868
5	3napC	0.592	4.27	0.057	0.891
6	4nwvA	0.590	4.22	0.097	0.874
7	3jbmA	0.590	4.40	0.135	0.891
8	5j96A	0.586	4.17	0.089	0.874
9	1b35C	0.584	4.31	0.038	0.891
10	5cdcB	0.584	4.49	0.031	0.914

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	7	1po11	J80	Rep, Mult	28,54,56,69,96
2	0.04	4	4niaA	NUC	Rep, Mult	1,2,3,51,54,147
3	0.04	4	1mqtA	SPL	Rep, Mult	28,50,52,54,111,112,113,124
4	0.03	3	1oopA	SPH	Rep, Mult	28,52,54,73,110,111,124
5	0.03	3	1al21	SPH	Rep, Mult	52,54,104,107,111,125
6	0.02	2	2hwe1	W54	Rep, Mult	28,29,56,68,69,70,141
7	0.02	2	1nd3A	W11	Rep, Mult	56,67,68,69,96
8	0.02	2	1c8m1	W11	Rep, Mult	9,55,57,69,70,71,124,126
9	0.02	2	2wff1	III	Rep, Mult	2,50,103,146,151
10	0.02	2	1vrh1	SD8	Rep, Mult	28,52,54,56,70,104
11	0.02	2	1fi1A	GMH	Rep, Mult	45,163
12	0.02	2	1eah1	SC4	Rep, Mult	28,49,52,54,56,111,113,124
13	0.02	2	1k5mA	SPH	Rep, Mult	48,54,111,113
14	0.02	2	3pcaM	DHB	Rep, Mult	29,32
15	0.01	1	3e3gB	SO4	Rep, Mult	57,95
16	0.01	1	1igxA	UUU	Rep, Mult	61,64,127
17	0.01	1	2rr11	W8R	Rep, Mult	56,89,90,91,96
18	0.01	1	1d4m1	W71	Rep, Mult	28,29,111,115,116,121,122,123,124,125
19	0.01	1	1hx6B	MPD	Rep, Mult	5,6,28,51,145
20	0.01	1	3aj0A	ZN	Rep, Mult	36,37,126,141

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1d3i1	0.566	4.44	0.059	0.874	3.6.1.15	NA
2	0.060	1kfxL	0.446	3.91	0.029	0.638	3.4.22.53	NA
3	0.060	1sdwA	0.449	4.32	0.029	0.684	4.3.2.5,1.14.17.3	NA
4	0.060	1piv1	0.561	4.45	0.066	0.874	3.4.22.29	NA
5	0.060	2aryA	0.300	5.79	0.038	0.575	3.4.22.52	NA
6	0.060	2cseA	0.479	4.71	0.034	0.770	2.7.7.50	NA
7	0.060	1gu3A	0.436	4.40	0.102	0.672	3.2.1.4	72
8	0.060	2bbvA	0.512	4.67	0.052	0.822	3.4.23.44	55
9	0.060	1pov0	0.555	4.25	0.040	0.851	3.4.22.29	66
10	0.060	1tme1	0.527	4.29	0.073	0.816	2.7.7.48	107,109,150
11	0.060	1h8tA	0.565	4.47	0.059	0.874	3.4.22.28	NA
12	0.060	1jew1	0.565	4.48	0.079	0.874	3.4.22.28	86,104,129
13	0.060	1zba1	0.474	4.51	0.030	0.736	3.6.1.15	NA
14	0.060	2nqaB	0.306	5.82	0.008	0.581	3.4.22.53,3.4.22.52	NA
15	0.060	1novC	0.512	4.89	0.058	0.845	3.4.23.44	69
16	0.060	1bev1	0.569	4.26	0.079	0.862	2.7.7.48	113
17	0.060	1h6yA	0.454	4.02	0.066	0.672	3.2.1.8	NA
18	0.060	1fmd2	0.546	4.33	0.055	0.839	3.4.22.46	92
19	0.060	1kgyA	0.459	3.93	0.067	0.672	2.7.10.1	143

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.07	0.558	4.57	0.06	0.88	5aooC	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0033644 GO:0034220 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0046718 GO:0051259
1	0.07	0.578	4.41	0.04	0.90	5j98C	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005524 GO:0006351 GO:0006508 GO:0008233 GO:0008234 GO:0016020 GO:0016740 GO:0016779 GO:0016787 GO:0019012 GO:0019028 GO:0033644 GO:0039694
2	0.07	0.585	4.30	0.03	0.89	5j98B	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005524 GO:0006351 GO:0006508 GO:0008233 GO:0008234 GO:0016020 GO:0016740 GO:0016779 GO:0016787 GO:0019012 GO:0019028 GO:0033644 GO:0039694
3	0.07	0.572	4.48	0.07	0.89	4qpgC	GO:0005198 GO:0019012 GO:0019028
4	0.07	0.608	4.11	0.08	0.89	2zzqA	GO:0003723 GO:0005198 GO:0016032 GO:0019012 GO:0019028 GO:0030430 GO:0039615 GO:0044228
5	0.07	0.562	4.58	0.06	0.88	1tmf3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019030 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039544 GO:0039548 GO:0039657 GO:0039694 GO:0039707 GO:0042025 GO:0044161 GO:0044162 GO:0044385 GO:0046718 GO:0046872 GO:0051259
6	0.07	0.560	4.45	0.04	0.86	1z7s3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006260 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0046872 GO:0051259 GO:0075509
7	0.07	0.562	4.42	0.07	0.86	1mqtC	GO:0005198 GO:0019012 GO:0019028
8	0.07	0.558	4.47	0.04	0.86	1pov3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0051259 GO:0075509
9	0.07	0.556	4.34	0.13	0.86	3zx8C	GO:0003723 GO:0005198 GO:0016032 GO:0019012 GO:0019028 GO:0039617
10	0.07	0.575	4.34	0.09	0.87	1c8nC	GO:0005198 GO:0019028 GO:0046872
11	0.07	0.556	4.52	0.04	0.86	1eah3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006260 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0019065 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0051259 GO:0075509
12	0.07	0.565	4.37	0.07	0.87	3dprC	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006260 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0051259 GO:0075509
13	0.07	0.558	4.59	0.07	0.89	5cfcB	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0019012 GO:0019028 GO:0019030 GO:0019062 GO:0030430 GO:0033644 GO:0034220 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0046718 GO:0051259
14	0.07	0.592	4.27	0.06	0.89	3napC	GO:0005198 GO:0019012 GO:0019028
15	0.07	0.559	4.42	0.07	0.86	1cov3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006260 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0046872 GO:0051259 GO:0075509
16	0.07	0.584	4.31	0.04	0.89	1b35C	GO:0005198 GO:0019012 GO:0019028 GO:0030430
17	0.07	0.559	4.42	0.08	0.86	1aym3	GO:0000166 GO:0001172 GO:0003723 GO:0003724 GO:0003968 GO:0004197 GO:0004386 GO:0005198 GO:0005216 GO:0005524 GO:0006260 GO:0006351 GO:0006508 GO:0006810 GO:0006811 GO:0008233 GO:0008234 GO:0016020 GO:0016032 GO:0016740 GO:0016779 GO:0016787 GO:0017111 GO:0018144 GO:0019012 GO:0019028 GO:0019062 GO:0030430 GO:0030683 GO:0033644 GO:0034220 GO:0039503 GO:0039520 GO:0039522 GO:0039540 GO:0039544 GO:0039611 GO:0039618 GO:0039657 GO:0039690 GO:0039694 GO:0039707 GO:0044161 GO:0044162 GO:0044385 GO:0044694 GO:0046718 GO:0051259 GO:0075509
18	0.07	0.556	4.64	0.07	0.87	4bipC	GO:0005198 GO:0019012 GO:0019028

Consensus prediction of GO terms

Molecular Function	GO:0003676	GO:0004175	GO:0008234	GO:0034062	GO:0032550	GO:0017111	GO:0032559	GO:0035639
GO-Score	0.48	0.37	0.37	0.37	0.37	0.37	0.37	0.37
Biological Processes	GO:0019538	GO:0019079	GO:0034645	GO:0039703	GO:0044033	GO:0010467	GO:0097659
GO-Score	0.37	0.37	0.37	0.37	0.37	0.37	0.37
Cellular Component	GO:0044423	GO:0033643	GO:0044218
GO-Score	0.58	0.37	0.37

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv1046c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]