Threading Zmax Znorm MUSTER 6.25 1.08 dPPAS 11.73 1.26 wdPPAS 12.06 1.30 wMUSTER 7.03 1.21 wPPAS 7.96 1.14 dPPAS2 19.39 1.85 PPAS 8.14 1.16 Env-PPAS 8.57 1.07 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.67 0.31+-0.10 12.5+-4.3 1842 0.020 model2 -2.67 1566 0.055 model3 -4.12 865 0.013 model4 -3.95 839 0.015 model5 -4.44 835 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).