Threading Zmax Znorm MUSTER 4.82 0.83 dPPAS 8.84 0.95 wdPPAS 9.71 1.04 wMUSTER 4.72 0.81 wPPAS 7.84 1.12 dPPAS2 17.03 1.62 PPAS 6.31 0.90 Env-PPAS 7.59 0.95 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.55 0.42+-0.14 11.9+-4.4 4104 0.076 model2 -4.04 1010 0.017 model3 -4.51 610 0.011 model4 -4.95 398 0.007 model5 -5.00 328 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).