Threading Zmax Znorm MUSTER 7.03 1.21 dPPAS 9.91 1.07 wdPPAS 10.35 1.11 wMUSTER 7.81 1.35 wPPAS 9.38 1.34 dPPAS2 19.60 1.87 PPAS 9.53 1.36 Env-PPAS 17.14 2.14 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=5271) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.99 0.48+-0.15 12.8+-4.2 1506 0.096 model2 -2.74 753 0.045 model3 -3.17 569 0.029 model4 -4.60 144 0.007 model5 -3.10 144 0.031 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).