Threading Zmax Znorm MUSTER 5.52 0.95 dPPAS 16.20 1.74 wdPPAS 15.51 1.67 wMUSTER 5.90 1.02 wPPAS 7.37 1.05 dPPAS2 31.45 3.00 PPAS 8.36 1.19 Env-PPAS 12.11 1.51 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=753) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.02 0.47+-0.15 12.4+-4.3 274 0.088 model2 -2.91 147 0.036 model3 -3.37 72 0.023 model4 -2.07 70 0.083 model5 -2.25 70 0.069 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).