I-TASSER results

Input Sequence in FASTA format

>protein (135 residues)
MPTGKVKWYDPDKGFGFLSQEGGEDVYVRSSALPTGVEALKAGQRVEFGIASGRRGPQAL
SLRLIEPPPSLSRPRREPAAEHKHSPDELHGMVEDMITLLESTVQPELRKGRYPDRKTAR
RVAEVVRAVAREFES

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MPTGKVKWYDPDKGFGFLSQEGGEDVYVRSSALPTGVEALKAGQRVEFGIASGRRGPQALSLRLIEPPPSLSRPRREPAAEHKHSPDELHGMVEDMITLLESTVQPELRKGRYPDRKTARRVAEVVRAVAREFES
Prediction	CCCCEEEEHCCCCCCEEEHCCCCCEEEEEHCCCCCCCCCCCCCEEEEEEEEHCCCCCCEEEEEEHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
Conf.Score	998668776589997567679998689886467768655799989999987589985456678977888764455554665589978999999999999987668467668999878999999999999999759
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MPTGKVKWYDPDKGFGFLSQEGGEDVYVRSSALPTGVEALKAGQRVEFGIASGRRGPQALSLRLIEPPPSLSRPRREPAAEHKHSPDELHGMVEDMITLLESTVQPELRKGRYPDRKTARRVAEVVRAVAREFES
Prediction	876140301277311000356726200001221554153055535141425627514304604414545545556455456674425301310330040025534651443432557505400500330065368
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120

                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCEEEEHCCCCCCEEEHCCCCCEEEEEHCCCCCCCCCCCCCEEEEEEEEHCCCCCCEEEEEEHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
MPTGKVKWYDPDKGFGFLSQEGGEDVYVRSSALPTGVEALKAGQRVEFGIASGRRGPQALSLRLIEPPPSLSRPRREPAAEHKHSPDELHGMVEDMITLLESTVQPELRKGRYPDRKTARRVAEVVRAVAREFES

3a0jA

0.40

0.21

0.52

1.97

MUSTER

MQKGRVKWFNAEKGYGFIEREGDTDVFVHYTAINKGFRTLNEGDIVTFDVEPGRKGPQAVNVTVVEPARR-----------------------------------------------------------------

2k5nA

0.21

0.11

0.54

2.06

dPPAS

AMNGTITTWFKDKGFGFIKDENGDNRYFHVIKV-ANPDLIKKDAAVTFEPTTNNKGLSAYAVKVVPLEHHHHHH-------------------------------------------------------------

2k5nA

0.21

0.11

0.54

3.01

wdPPAS

AMNGTITTWFKDKGFGFIKDENGDNRYFHVIKV-ANPDLIKKDAAVTFEPTTNNKGLSAYAVKVVPLEHHHHHH-------------------------------------------------------------

2k5nA

0.21

0.11

0.54

2.33

wMUSTER

AMNGTITTWFKDKGFGFIKDENGDNRYFHVIKV-ANPDLIKKDAAVTFEPTTNNKGLSAYAVKVVPLEHHHHHH-------------------------------------------------------------

1g6pA

0.49

0.24

0.48

2.59

wPPAS

M-RGKVKWFDSKKGYGFITKDEGGDVFVHWSAIEEGFKTLKEGQVVEFEIQEGKKGPQAAHVKVVE---------------------------------------------------------------------

2k5nA

0.21

0.11

0.54

3.77

dPPAS2

AMNGTITTWFKDKGFGFIKDENGDNRYFHVIKV-ANPDLIKKDAAVTFEPTTNNKGLSAYAVKVVPLEHHHHHH-------------------------------------------------------------

1g6pA

0.49

0.24

0.48

2.49

PPAS

M-RGKVKWFDSKKGYGFITKDEGGDVFVHWSAIEEGFKTLKEGQVVEFEIQEGKKGPQAAHVKVVE---------------------------------------------------------------------

1g6pA

0.49

0.24

0.48

2.15

Env-PPAS

M-RGKVKWFDSKKGYGFITKDEGGDVFVHWSAIEEGFKTLKEGQVVEFEIQEGKKGPQAAHVKVVE---------------------------------------------------------------------

2k5nA

0.21

0.11

0.54

1.97

MUSTER

AMNGTITTWFKDKGFGFIKDENGDNRYFHVIKV-ANPDLIKKDAAVTFEPTTNNKGLSAYAVKVVPLEHHHHHH-------------------------------------------------------------

1g6pA

0.48

0.23

0.48

1.99

dPPAS

-MRGKVKWFDSKKGYGFITKDEGGDVFVHWSAIEEGFKTLKEGQVVEFEIQEGKKGPQAAHVKVVE---------------------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.34

Estimated TM-score = 0.44±0.14

Estimated RMSD = 9.7±4.6Å

Download Model 2

C-score=-2.30

Download Model 3

C-score=-2.54

Download Model 4

C-score=-2.32

Download Model 5

C-score=-2.90

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3sqgA1	0.490	4.03	0.036	0.741
2	3kjpA	0.483	3.84	0.105	0.719
3	2z6bA	0.480	4.29	0.103	0.756
4	3m7nA	0.478	3.77	0.032	0.681
5	4ifdI	0.474	3.85	0.083	0.689
6	3trzA	0.474	2.98	0.242	0.593
7	4q5vA3	0.472	4.42	0.072	0.807
8	3k5nA	0.469	4.92	0.069	0.815
9	3m07A2	0.468	4.70	0.044	0.785
10	3aqqA	0.466	2.53	0.224	0.563

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	7	3trzB	QNA	Rep, Mult	7,8,9,10,11,12,13,15,17,25,27,29,30,31,32,42,53,55,56,57,58
2	0.10	5	4a75A	NUC	Rep, Mult	7,8,10,15,17,25,27,29,53,55,57,58
3	0.06	4	3trzA	NUC	Rep, Mult	9,10
4	0.05	3	3pf5A	NUC	Rep, Mult	8,17,25
5	0.04	3	3trzB	NUC	Rep, Mult	15,27,53,55,56,57,58
6	0.04	3	3trzB	NUC	Rep, Mult	11,12,13,27,29,30,31,32,37,38,55
7	0.04	3	3trzB	NUC	Rep, Mult	80,82,83,84,96,97,98
8	0.03	2	1c9oB	NA	Rep, Mult	19,20,22,23
9	0.03	2	3trzA	NUC	Rep, Mult	7,8
10	0.03	2	3ts0A	NUC	Rep, Mult	15,27,29,31,32,55
11	0.02	2	3ts0B	NUC	Rep, Mult	85,106,107,110,111,112,113
12	0.02	1	2es2A	CA	Rep, Mult	1,3
13	0.01	1	3ts2A	NUC	Rep, Mult	30,36,37,38
14	0.01	1	3trzA	UUU	Rep, Mult	84,97,103
15	0.01	1	3ts2A	UUU	Rep, Mult	41,113,116
16	0.01	1	3ts2A	NUC	Rep, Mult	36,37,76
17	0.01	1	2bxyA	TRE	Rep, Mult	32,33,36,61,62
18	0.01	1	3ts2A	NUC	Rep, Mult	12,76

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2gjtA	0.440	3.92	0.095	0.644	3.1.3.48	NA
2	0.060	1zklA	0.425	5.03	0.095	0.763	3.1.4.17	34,37,122
3	0.060	3ebgA	0.436	4.91	0.052	0.726	3.4.11.-	NA
4	0.060	1p4oB	0.403	4.40	0.099	0.674	2.7.10.1,2.7.1.112	25,29
5	0.060	1zvuA	0.428	4.70	0.068	0.741	5.99.1.-	NA
6	0.060	1is9A	0.375	5.03	0.040	0.696	3.2.1.4	NA
7	0.060	3iceC	0.448	4.31	0.109	0.704	3.6.1.-	88
8	0.060	3go6A	0.432	4.65	0.064	0.741	2.7.1.15	62
9	0.060	2wodA	0.436	4.45	0.103	0.689	3.2.2.24	NA
10	0.060	1l8kA	0.380	4.77	0.113	0.659	3.1.3.48	63
11	0.060	1lf6A	0.343	5.69	0.035	0.704	3.2.1.3	47,124
12	0.060	1wchA	0.428	3.93	0.089	0.644	3.1.3.48	NA
13	0.060	2qxfA	0.439	4.76	0.074	0.756	3.1.11.1	NA
14	0.060	2iobB	0.432	5.29	0.046	0.822	3.5.1.78,6.3.1.8	NA
15	0.060	1mc0A	0.325	5.35	0.053	0.578	3.1.4.17	NA
16	0.060	1po5A	0.403	4.70	0.117	0.704	1.14.14.1	NA
17	0.060	2r8qA	0.444	4.99	0.079	0.778	3.1.4.17	NA
18	0.060	3ecnB	0.444	5.38	0.081	0.830	3.1.4.17	NA
19	0.060	3m07A	0.468	4.68	0.044	0.785	3.2.1.141	95,97

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.22	0.464	1.84	0.20	0.53	2k5nA	GO:0003677 GO:0006355
1	0.07	0.483	3.84	0.10	0.72	3kjpA	GO:0000723 GO:0000781 GO:0000783 GO:0000784 GO:0003677 GO:0005634 GO:0005654 GO:0005694 GO:0007004 GO:0010521 GO:0016233 GO:0017151 GO:0032202 GO:0032212 GO:0032508 GO:0042162 GO:0043047 GO:0051096 GO:0051973 GO:0051974 GO:0060383 GO:0070187 GO:0070200 GO:0098505
2	0.07	0.480	4.29	0.10	0.76	2z6bA	GO:0003796 GO:0003824 GO:0008152 GO:0009253 GO:0016787 GO:0016798 GO:0016998 GO:0019012 GO:0019076 GO:0019835 GO:0033922 GO:0042742 GO:0046718 GO:0085027 GO:0098025
3	0.07	0.486	4.06	0.04	0.75	3sqgA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
4	0.07	0.451	4.44	0.05	0.73	1e6yA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
5	0.07	0.437	4.53	0.07	0.73	1hbmA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
6	0.06	0.457	3.90	0.04	0.68	2i0qA	GO:0000723 GO:0000781 GO:0000784 GO:0003677 GO:0005634 GO:0005694 GO:0016233 GO:0043047
7	0.06	0.357	5.02	0.00	0.64	3v2yA	GO:0001525 GO:0001664 GO:0001955 GO:0003245 GO:0003376 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005768 GO:0005829 GO:0005886 GO:0006935 GO:0007155 GO:0007165 GO:0007186 GO:0007193 GO:0007420 GO:0008152 GO:0008284 GO:0009253 GO:0009897 GO:0016020 GO:0016021 GO:0016477 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019226 GO:0019835 GO:0030032 GO:0030155 GO:0030182 GO:0030335 GO:0030430 GO:0030500 GO:0031226 GO:0031532 GO:0038036 GO:0042742 GO:0043547 GO:0045121 GO:0045124 GO:0045446 GO:0045944 GO:0046625 GO:0048661 GO:0050927 GO:0051482 GO:0051497 GO:0061384 GO:0072678
8	0.06	0.361	5.23	0.02	0.70	1e6vA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
9	0.06	0.395	4.64	0.05	0.65	4phuA	GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005085 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0008152 GO:0008289 GO:0009253 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030073 GO:0030430 GO:0032024 GO:0042593 GO:0042742 GO:0043547 GO:0045125 GO:0051928 GO:0070542
10	0.06	0.354	5.27	0.04	0.67	3hzuA	GO:0004792 GO:0005618 GO:0005829 GO:0005886 GO:0016740
11	0.06	0.356	5.28	0.03	0.69	4u14A	GO:0003056 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006939 GO:0007165 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007586 GO:0008144 GO:0008152 GO:0009253 GO:0016020 GO:0016021 GO:0016323 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019229 GO:0019835 GO:0030054 GO:0030425 GO:0030430 GO:0032279 GO:0042166 GO:0042742 GO:0043679 GO:0045202 GO:0045211 GO:0045987 GO:0046541
12	0.06	0.323	5.01	0.08	0.57	1qzgA	GO:0000723 GO:0000781 GO:0000783 GO:0000784 GO:0003677 GO:0005634 GO:0005694 GO:0005724 GO:0005829 GO:0010521 GO:0016233 GO:0032211 GO:0043047 GO:0051974 GO:0070187 GO:0098505
13	0.06	0.346	5.40	0.06	0.69	1ei5A	GO:0004177 GO:0006508 GO:0008233 GO:0016787
14	0.06	0.299	5.68	0.07	0.61	4k5yA	GO:0003796 GO:0003824 GO:0004871 GO:0004888 GO:0004930 GO:0005768 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007166 GO:0007186 GO:0007190 GO:0007565 GO:0007567 GO:0008152 GO:0009253 GO:0010578 GO:0010579 GO:0015056 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030430 GO:0031226 GO:0042742 GO:0051458 GO:0071376 GO:1901386 GO:2000852
15	0.06	0.371	4.90	0.05	0.67	5d5aA	GO:0001666 GO:0001889 GO:0001965 GO:0001993 GO:0002024 GO:0002025 GO:0002028 GO:0002032 GO:0002086 GO:0003059 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004935 GO:0004941 GO:0005634 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005886 GO:0005887 GO:0005901 GO:0006898 GO:0006940 GO:0007165 GO:0007166 GO:0007171 GO:0007186 GO:0007188 GO:0007189 GO:0007190 GO:0007267 GO:0007565 GO:0007568 GO:0008144 GO:0008152 GO:0008179 GO:0008284 GO:0008306 GO:0008333 GO:0009253 GO:0009409 GO:0010765 GO:0015459 GO:0016020 GO:0016021 GO:0016324 GO:0016525 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0019899 GO:0030279 GO:0030424 GO:0030425 GO:0030430 GO:0030501 GO:0031398 GO:0031649 GO:0031713 GO:0032403 GO:0032570 GO:0032781 GO:0032809 GO:0033574 GO:0035240 GO:0035249 GO:0035255 GO:0035811 GO:0040015 GO:0042060 GO:0042312 GO:0042383 GO:0042742 GO:0042803 GO:0043065 GO:0043197 GO:0043231 GO:0043235 GO:0043268 GO:0043410 GO:0043627 GO:0044849 GO:0045453 GO:0045823 GO:0045909 GO:0045944 GO:0045986 GO:0048633 GO:0050728 GO:0050873 GO:0051379 GO:0051380 GO:0051924 GO:0051930 GO:0060079 GO:0071456 GO:0071548 GO:0071867 GO:0071880 GO:0090331 GO:0097421 GO:1901098 GO:1904504 GO:1904925
16	0.06	0.361	5.19	0.00	0.67	3uonA	GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006940 GO:0007165 GO:0007186 GO:0007187 GO:0007188 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007399 GO:0008016 GO:0008144 GO:0008152 GO:0009253 GO:0009615 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019835 GO:0030054 GO:0030425 GO:0030430 GO:0032279 GO:0032280 GO:0042742 GO:0043025 GO:0043679 GO:0045202 GO:0045211
17	0.06	0.369	4.83	0.03	0.66	5dsgB	GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005085 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007166 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0008152 GO:0008283 GO:0009253 GO:0010033 GO:0014069 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019835 GO:0030054 GO:0030430 GO:0032279 GO:0040012 GO:0042383 GO:0042742 GO:0043025 GO:0043547 GO:0043679 GO:0045202 GO:0045211
18	0.06	0.368	4.74	0.06	0.64	1u1wB	GO:0002047 GO:0003824 GO:0009058 GO:0009405 GO:0016853 GO:0017000
19	0.06	0.363	5.00	0.03	0.67	3pblA	GO:0000122 GO:0001588 GO:0001591 GO:0001963 GO:0001975 GO:0002016 GO:0002031 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004952 GO:0005886 GO:0005887 GO:0006874 GO:0007165 GO:0007186 GO:0007191 GO:0007194 GO:0007195 GO:0007212 GO:0007611 GO:0007612 GO:0007626 GO:0008144 GO:0008152 GO:0008284 GO:0008542 GO:0009253 GO:0014059 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019216 GO:0019835 GO:0019904 GO:0030139 GO:0030430 GO:0030814 GO:0031748 GO:0032416 GO:0032467 GO:0032922 GO:0034776 GO:0035176 GO:0035240 GO:0035483 GO:0035815 GO:0040012 GO:0040014 GO:0042220 GO:0042417 GO:0042493 GO:0042742 GO:0042995 GO:0043278 GO:0045177 GO:0045187 GO:0045471 GO:0045776 GO:0045840 GO:0045944 GO:0046717 GO:0048148 GO:0048715 GO:0050482 GO:0050709 GO:0050883 GO:0051584 GO:0051898 GO:0060134 GO:0060160 GO:0060161 GO:0090325

Consensus prediction of GO terms

Molecular Function	GO:0003676
GO-Score	0.54
Biological Processes	GO:0006351	GO:1903506	GO:2000112	GO:0010468
GO-Score	0.43	0.43	0.43	0.43
Cellular Component	GO:0070187	GO:0005654	GO:0098025
GO-Score	0.07	0.07	0.07

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0871

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]