I-TASSER results

Input Sequence in FASTA format

>protein (270 residues)
MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVPGLSVLDVGCGPGTITVDLAAR
VVPGSVTGVEPTDDALSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHV
ADPVRALQEMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEPDAG
RRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQSDLAHQLVDSGLATAAQ
LEEISTAWREWAAAPDGWLAIPHGEILCRA

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDALSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQEMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQSDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA
Prediction	CCCCCCCCHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCCHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHHHHCCCCEEEEHCCHHHCCCCCCCCEEEEEHCHHHHCCCHHHHHHHHHHHHCCCEEEEEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEHC
Conf.Score	986555534468657899999999999999998866999957999779988999999997699799999599999999999999989997599985655599998876478874447778899999999999848995999997788887667767899999999999998758998668999999999899858999999996887788999999998876557999999987999999999999999999789948998768999869
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDALSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQEMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQSDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA
Prediction	875544531220122411430322103400430054044423040001101300020063047030000211460053026206747154031220102504135612000000000110431430030012002230100000012432212242410430141034014334131211540350266051650424333232435413310131123203445224302743213462044015104501733400000000001037
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCCHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHHHHCCCCEEEEHCCHHHCCCCCCCCEEEEEHCHHHHCCCHHHHHHHHHHHHCCCEEEEEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEHC
MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDALSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQEMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQSDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA

3mggA

0.21

0.19

0.89

2.38

MUSTER

--------------------------ETLEKLLHHDYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.20

0.18

0.90

3.15

dPPAS

------------------------ETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.20

0.18

0.90

3.19

wdPPAS

------------------------ETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.21

0.19

0.90

2.83

wMUSTER

-----------------------ETLEKLLHHDT-VYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.20

0.18

0.90

3.33

wPPAS

------------------------ETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.20

0.18

0.90

4.49

dPPAS2

------------------------ETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.21

0.19

0.90

3.04

PPAS

-----------------------ETLEKLLHHDT-VYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

3mggA

0.21

0.19

0.90

3.61

Env-PPAS

-----------------------ETLEKLLHHDT-VYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYK-GNSLVGRQIYPLLQESGFEKIRVEPRVYIDSSK-PELVDGFILKTIIPVEGVKEQSLKQ-IIKEEEWEKGIEELHKTA-EHGGTFCYTFFKGWGTK

5egpA

0.17

0.16

0.96

1.90

MUSTER

MFQTKSDRY---YTEKLTGLYAQTLVDYSG--VANTSQKPLVVLDNACGIGAVSSVLNHTLQDWKLTCGDLSEGMLETTKRRLQDEGWVNAETKIVNALDTGLPDGHYTHVFVAFGFQSFPDANAALKECFRILASGGILASSTWQ--NFNWIPIMKAAIEFPTQKEFITLHNAGWDS-ESYIQSELEKLGFRDVKVIPVPKETSIPIDEFFEVCMMIIPYLLPKFWTEEQRESH--EKDVPMVLRQYLQDTYGANGQVPLEAVALITTG

1vl5A

0.22

0.18

0.82

2.19

dPPAS

-------------------------GSDLAKLQIAALKGNEEVLDVATGGGHVANAFAPFV--KKVVAFDLTEDILKVARAFIEGNGHQQVEYVQGDAE-QPFTDERFHIVTCRIAAHHFPNPASFVSEAYRVLKKGGQLLLVDNSA------PENDAFDVFYNYVEKERDYSHHRAWK-KSDWLKLEEAGFELEELHCFHKTFI--------FEDWCDRNVTTEKKQELSDFIKSKPTEYYQKFK-----IVVEDGRVYSFRGESILKA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.79

Estimated TM-score = 0.82±0.08

Estimated RMSD = 4.3±2.9Å

Download Model 2

C-score=-2.21

Download Model 3

C-score=-3.16

Download Model 4

C-score=-2.93

Download Model 5

C-score=-4.45

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3mggA	0.848	1.56	0.207	0.896
2	5egpA	0.747	3.77	0.133	0.944
3	3g5tA	0.737	3.60	0.127	0.930
4	2gh1A	0.723	3.85	0.156	0.900
5	2yqzA	0.707	4.00	0.143	0.907
6	1m6eX	0.702	4.48	0.073	0.952
7	5f2kA	0.694	4.30	0.097	0.930
8	2eg5E	0.687	4.25	0.087	0.918
9	2aoxA	0.675	4.42	0.104	0.922
10	3egeA	0.668	3.63	0.159	0.833

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.61	36	4qnuH	GEK	Rep, Mult	26,46,47,49,70,71,72,75,97,98,99,114,115,116,118,120,263
2	0.03	2	1p91A	SAM	Rep, Mult	47,48,49,50,51,52,53,114,115,144,145,150,263

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.347	1wznA	0.595	3.38	0.179	0.719	2.1.1.-	55
2	0.308	2p35A	0.626	3.94	0.159	0.804	2.1.1.144	47,50,67,74,93,97,116,118,120
3	0.212	3g5tA	0.737	3.60	0.127	0.930	2.1.1.145	13,48,52
4	0.155	3e05D	0.553	3.08	0.101	0.656	2.1.1.132	76
5	0.148	3bgdA	0.579	3.61	0.142	0.722	2.1.1.67	NA
6	0.145	2iftA	0.474	3.68	0.125	0.593	2.1.1.52	60
7	0.077	3e05B	0.555	3.09	0.100	0.659	2.1.1.132	54
8	0.073	1f38A	0.540	3.09	0.163	0.644	2.1.1.-	NA
9	0.070	3hnrA	0.539	3.62	0.151	0.663	2.1.1.-	NA
10	0.067	2cl5A	0.548	3.06	0.125	0.648	2.1.1.6	NA
11	0.067	3bwmA	0.548	3.07	0.119	0.648	2.1.1.6	NA
12	0.067	3grzB	0.506	3.05	0.142	0.596	2.1.1.-	NA
13	0.066	3gdhA	0.520	3.12	0.127	0.615	2.1.1.-	NA
14	0.060	1kyzE	0.592	3.26	0.104	0.711	2.1.1.68	173,175
15	0.060	1p91A	0.643	3.64	0.162	0.796	2.1.1.51	187
16	0.060	3lccA	0.583	3.21	0.132	0.696	2.1.1.-	47,55,76,92
17	0.060	2pxxA	0.561	2.75	0.206	0.644	3.4.24.71	NA
18	0.060	2a14A	0.597	3.66	0.137	0.741	2.1.1.49	13,47,49,73,98
19	0.060	1jq3A	0.565	3.49	0.096	0.696	2.5.1.16	47
20	0.060	1fp2A	0.580	3.31	0.143	0.700	2.1.1.150	NA
21	0.060	2h11B	0.586	3.49	0.137	0.722	2.1.1.67	10
22	0.060	2ip2A	0.590	3.49	0.134	0.719	2.1.1.-	NA
23	0.060	1xcjA	0.571	3.37	0.117	0.700	2.1.1.2	53
24	0.060	1sqfA	0.554	3.80	0.096	0.681	2.1.1.-	NA
25	0.060	3i58A	0.597	3.00	0.147	0.707	2.1.1.-	NA
26	0.060	1kywC	0.585	3.42	0.109	0.707	2.1.1.68	NA
27	0.060	1ri5A	0.591	4.08	0.152	0.767	2.1.1.56	47,97
28	0.060	2aovA	0.673	4.43	0.112	0.911	2.1.1.8	71
29	0.060	1l1eA	0.634	4.47	0.099	0.844	2.1.1.79	NA
30	0.060	1xxlA	0.624	3.65	0.153	0.774	2.1.1.-	NA
31	0.060	2iipA	0.599	3.67	0.152	0.741	2.1.1.1	47,49,73,76,97
32	0.060	2ex4A	0.599	3.19	0.162	0.722	2.1.1.-	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.41	0.868	1.74	0.19	0.93	3mggB	GO:0008168 GO:0016740 GO:0032259
1	0.38	0.558	3.42	0.16	0.69	2p8jB	GO:0008152 GO:0008168 GO:0016740 GO:0032259
2	0.35	0.575	2.85	0.16	0.66	3l8dA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
3	0.32	0.579	3.14	0.20	0.69	3sm3A	GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0046872
4	0.31	0.473	2.65	0.16	0.54	5bxyA	GO:0008168 GO:0032259
5	0.29	0.530	2.81	0.16	0.61	1dusA	GO:0008168 GO:0016740 GO:0032259
6	0.29	0.638	3.80	0.16	0.81	2p35A	GO:0005737 GO:0008168 GO:0016740 GO:0030798 GO:0032259
7	0.29	0.644	4.23	0.26	0.83	3busA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
8	0.27	0.601	3.94	0.19	0.76	4necB	GO:0008168 GO:0016740 GO:0032259
9	0.27	0.613	3.65	0.15	0.76	4htfB	GO:0008033 GO:0008168 GO:0016740 GO:0032259
10	0.27	0.509	3.51	0.16	0.63	2i6gB	GO:0005737 GO:0008168 GO:0008757 GO:0016740 GO:0032259 GO:0046690
11	0.26	0.627	3.64	0.16	0.77	2gluA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0016740 GO:0032259
12	0.26	0.604	3.31	0.22	0.72	2gs9A	GO:0008152 GO:0008168 GO:0032259
13	0.25	0.675	3.65	0.16	0.84	3egeA	GO:0008152 GO:0008168 GO:0032259
14	0.25	0.710	3.95	0.13	0.91	2yqzA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
15	0.25	0.606	3.26	0.20	0.72	1vlmA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0032259
16	0.24	0.653	4.32	0.15	0.85	4krhA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
17	0.23	0.598	2.80	0.18	0.69	3dh0B	GO:0005737 GO:0008757 GO:0032259 GO:0046872 GO:0051536 GO:0051539
18	0.23	0.670	4.18	0.20	0.85	4pneB	GO:0008152 GO:0008168 GO:0016740 GO:0032259
19	0.23	0.747	3.77	0.13	0.94	5egpA	GO:0008168 GO:0016740 GO:0032259
20	0.23	0.546	2.78	0.14	0.63	3jwhA	GO:0001510 GO:0008171 GO:0008173
21	0.22	0.553	3.21	0.14	0.66	3jwgA	GO:0001510 GO:0008168 GO:0008171 GO:0008173 GO:0016740 GO:0032259
22	0.21	0.644	3.85	0.15	0.83	3ccfB	GO:0008152 GO:0008168 GO:0016740 GO:0030798 GO:0032259
23	0.21	0.651	4.17	0.15	0.84	4ineA	GO:0000773 GO:0005737 GO:0006656 GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0080101
24	0.21	0.583	3.21	0.13	0.70	3lccA	GO:0005886 GO:0006952 GO:0008168 GO:0008757 GO:0016740 GO:0018708 GO:0019762 GO:0032259
25	0.21	0.621	4.13	0.14	0.80	4iv8A	GO:0000234 GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
26	0.20	0.573	3.25	0.21	0.69	3e23A	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
27	0.20	0.541	3.12	0.18	0.64	3mb5A	GO:0008033 GO:0008168 GO:0016429 GO:0016740 GO:0030488 GO:0031515 GO:0032259
28	0.20	0.641	4.30	0.14	0.83	3f4kA	GO:0005737 GO:0008168 GO:0008757 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
29	0.20	0.540	3.09	0.16	0.64	1f38A	GO:0006479 GO:0008168 GO:0008276 GO:0009236 GO:0016740 GO:0032259 GO:0046140
30	0.20	0.631	3.76	0.16	0.78	1vl5A	GO:0008152 GO:0008168 GO:0016740 GO:0032259
31	0.20	0.606	3.11	0.20	0.71	1ve3B	GO:0046872 GO:0051536 GO:0051539
32	0.19	0.506	3.05	0.14	0.60	3grzB	GO:0005737 GO:0006479 GO:0008168 GO:0008276 GO:0016740 GO:0032259
33	0.19	0.616	3.70	0.17	0.76	4obwC	GO:0005739 GO:0005743 GO:0005759 GO:0006744 GO:0008168 GO:0009060 GO:0016020 GO:0016740 GO:0031314 GO:0032259 GO:0043334 GO:0102005
34	0.19	0.588	3.06	0.15	0.70	4qdkA	GO:0005737 GO:0008168 GO:0008757 GO:0015979 GO:0015995 GO:0016740 GO:0032259 GO:0036068 GO:0046406
35	0.19	0.461	3.35	0.13	0.56	3ckkA	GO:0000049 GO:0003723 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0006400 GO:0008033 GO:0008168 GO:0008176 GO:0016740 GO:0030488 GO:0032259 GO:0036265 GO:0043527
36	0.18	0.634	4.59	0.13	0.85	3kkzA	GO:0046872 GO:0051536 GO:0051539
37	0.18	0.557	3.63	0.15	0.68	3dtnA	GO:0046872
38	0.18	0.492	3.52	0.15	0.60	3cggA	GO:0008168 GO:0016740 GO:0032259
39	0.18	0.522	3.69	0.13	0.67	2kw5A	GO:0005737 GO:0008757 GO:0032259
40	0.18	0.599	3.58	0.15	0.74	2i62B	GO:0005737 GO:0005829 GO:0008112 GO:0008168 GO:0010243 GO:0016740 GO:0031100 GO:0032259 GO:0042493
41	0.18	0.626	3.76	0.19	0.79	5je1A	GO:0008168 GO:0016740 GO:0032259
42	0.18	0.636	4.51	0.15	0.84	3e7pA	GO:0046872 GO:0051536 GO:0051539
43	0.18	0.590	3.46	0.19	0.71	3d2lC	GO:0008168 GO:0016740 GO:0032259
44	0.17	0.479	3.10	0.11	0.56	3dxxA	GO:0006400 GO:0008033 GO:0008168 GO:0008176 GO:0016740 GO:0030488 GO:0032259 GO:0036265 GO:0043527
45	0.17	0.624	4.29	0.14	0.81	2o57A
46	0.17	0.636	3.53	0.14	0.78	3ggdA
47	0.17	0.546	3.01	0.20	0.63	2b3tA	GO:0003676 GO:0006415 GO:0006479 GO:0008168 GO:0008276 GO:0008757 GO:0010468 GO:0016740 GO:0018364 GO:0032259 GO:0036009
48	0.16	0.498	3.04	0.12	0.59	1jsxA	GO:0005737 GO:0005829 GO:0006364 GO:0008168 GO:0008649 GO:0016740 GO:0032259 GO:0070043 GO:0070475 GO:0070476
49	0.16	0.498	2.79	0.11	0.57	2fcaA	GO:0006400 GO:0008033 GO:0008168 GO:0008176 GO:0016740 GO:0032259 GO:0036265 GO:0043527
50	0.15	0.520	3.12	0.13	0.61	3gdhA	GO:0000387 GO:0001510 GO:0005615 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0008168 GO:0008173 GO:0009452 GO:0015030 GO:0016740 GO:0022613 GO:0030532 GO:0032259 GO:0036261 GO:0044255 GO:0071164 GO:0071167
51	0.15	0.537	2.82	0.13	0.63	4qpnA	GO:0005622 GO:0005737 GO:0008168 GO:0016740 GO:0032259
52	0.15	0.587	3.91	0.18	0.74	1bhjA	GO:0001887 GO:0005542 GO:0005634 GO:0005737 GO:0005829 GO:0006544 GO:0008168 GO:0008757 GO:0016594 GO:0016740 GO:0017174 GO:0032259 GO:0046498 GO:0046500 GO:0046655 GO:0051262 GO:0051289 GO:0098603 GO:1901052
53	0.14	0.538	3.13	0.17	0.64	5c1iB	GO:0008033 GO:0008168 GO:0016429 GO:0016740 GO:0030488 GO:0031515 GO:0032259
54	0.13	0.608	3.98	0.18	0.77	4p7cA	GO:0002098 GO:0006400 GO:0008033 GO:0016300 GO:0016740 GO:0016765 GO:0030488
55	0.12	0.507	3.11	0.20	0.60	3g07A	GO:0000122 GO:0001510 GO:0008168 GO:0008173 GO:0008757 GO:0016073 GO:0016740 GO:0032259 GO:0035562 GO:0040031 GO:0044822 GO:1900087
56	0.11	0.583	3.63	0.17	0.71	4kdcA	GO:0005829 GO:0006744 GO:0008168 GO:0008425 GO:0008689 GO:0008757 GO:0016740 GO:0032259 GO:0043431 GO:0061542 GO:0102004
57	0.10	0.598	3.03	0.15	0.71	2r3sA
58	0.09	0.529	3.29	0.11	0.64	2hnkB	GO:0008168 GO:0008171 GO:0016740 GO:0032259
59	0.09	0.673	3.90	0.16	0.86	3bkxA	GO:0008168 GO:0016740 GO:0032259
60	0.09	0.653	3.70	0.16	0.81	1p91A	GO:0005737 GO:0006364 GO:0008168 GO:0008270 GO:0008989 GO:0016740 GO:0032259 GO:0046872 GO:0052911 GO:0070475
61	0.08	0.583	3.82	0.17	0.74	3bkwA	GO:0008152 GO:0008168 GO:0032259
62	0.08	0.599	3.17	0.16	0.72	5cvdA	GO:0005634 GO:0005654 GO:0005737 GO:0006480 GO:0007051 GO:0007059 GO:0008168 GO:0008276 GO:0016740 GO:0018011 GO:0018012 GO:0018016 GO:0032259 GO:0035572 GO:0035573 GO:0071885
63	0.07	0.644	3.99	0.10	0.82	4f86A	GO:0008168 GO:0008169 GO:0008757 GO:0016740 GO:0032259 GO:0042214
64	0.07	0.590	3.93	0.11	0.75	4gekG	GO:0002098 GO:0008168 GO:0016300 GO:0016740 GO:0016743 GO:0030488 GO:0032259 GO:1904047
65	0.07	0.525	2.69	0.16	0.61	3evzA	GO:0008168 GO:0032259
66	0.07	0.495	2.88	0.17	0.58	3i9fB	GO:0008152 GO:0008168 GO:0032259 GO:0046872
67	0.07	0.522	3.59	0.15	0.64	3cc8A
68	0.07	0.507	2.79	0.13	0.59	2gpyB	GO:0008168 GO:0008171 GO:0016740 GO:0032259 GO:0046872
69	0.07	0.614	4.06	0.15	0.78	4qnuA	GO:0002098 GO:0006400 GO:0008033 GO:0016300 GO:0016740 GO:0016765 GO:0030488
70	0.07	0.542	3.73	0.12	0.68	5bp9A	GO:0008168 GO:0016740 GO:0032259
71	0.07	0.547	3.44	0.10	0.68	4ymgB	GO:0008171 GO:0032259 GO:0046872 GO:0051536 GO:0051539
72	0.07	0.499	2.99	0.11	0.57	1yzhB	GO:0006400 GO:0008033 GO:0008168 GO:0008176 GO:0016740 GO:0032259 GO:0036265

Consensus prediction of GO terms

Molecular Function	GO:0008168	GO:0046872
GO-Score	0.89	0.32
Biological Processes	GO:0032259
GO-Score	0.89
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0839

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]