I-TASSER results

I-TASSER results for job id Rv0798c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (265 residues)
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKA
PTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIF
EGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTK
VSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTD
TVRLYLQETLTFLCYTAEASVALSH

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTDTVRLYLQETLTFLCYTAEASVALSH
Prediction	CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHCCCCCCCCEEEEHCCEEEHCCCCCCCEEEEEEEEEEEEEEEEEEEHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEHCCCCCEEEEHCCCCCEEEEEEEEEEEEEHCCCCCEEEEEEEEEEEEEHCCCCEEEEHCC
Conf.Score	9765556789999999999999999999863456788757888986578856757765678888778778988878999868976999999999599999789999999999999999997876659977545788765558888679999999999999998998986899889999889853689864899999997898799666688799978999768998754677775578988999999999998759876999859
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTDTVRLYLQETLTFLCYTAEASVALSH
Prediction	6542436413136610540252025004520100010304234314132132131452554664142342432301302340403241032045464324153035004300420140014016724052036366454151464354015101500430373416210000003610430152274413125204511736102011042000002444301000001111013337644020102000001033260002038
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHCCCCCCCCEEEEHCCEEEHCCCCCCCEEEEEEEEEEEEEEEEEEEHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEHCCCCCEEEEHCCCCCEEEEEEEEEEEEEHCCCCCEEEEEEEEEEEEEHCCCCEEEEHCC
MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTDTVRLYLQETLTFLCYTAEASVALSH

3dktA

0.35

0.99

3.66

MUSTER

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

7.22

dPPAS

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLRGGIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

7.57

wdPPAS

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.34

0.99

4.20

wMUSTER

-EFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

6.13

wPPAS

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

14.99

dPPAS2

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLRGGIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

5.54

PPAS

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

3dktA

0.35

0.99

7.75

Env-PPAS

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEER-KIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLK-

4pt2P

0.23

0.99

3.03

MUSTER

PDFLGHAENPLREEEWARLNETVIQVARRSLVGRRILDIYGPLGAGVQTVPYDEFQGVSPGTAMVFTDARKFKTIPIIYKDFLLHWRDIEAARTHNMPLDVSAAAGAAALCAQQEDELIFYGDARLGYEGLMTANGRLTVPLGDWPGGGFQAIVEATRKLNEQGHFGPYAVVLSPRLYSQLHRIYETGVLEIETIRQLASDGVYQSNRLRGGVVVSTGRENMDLAVSMDMVAAYLGASRMNHPFRVLEALLLRIKHPDAICTL--

4pt2P

0.23

0.99

5.39

dPPAS

PDFLGHAENPLREEEWARLNETVIQVARRSLVGRRILDIYGPLGAGVQTVPYDEFQGVSPGTAMVFTDARKFKTIPIIYKDFLLHWRDIEAARTHNMPLDVSAAAGAAALCAQQEDELIFYGDARLGYEGLMTANGRLTVPLGDWPGGGFQAIVEATRKLNEQGHFGPYAVVLSPRLYSQLHRIYETGVLEIETIRQLASDGVYQSNRLRGGVVVSTGRENMDLAVSMDMVAAYLGASRMNHPFRVLEALLLRIKHPDAICTL--

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 2 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=2.00

Estimated TM-score = 0.99±0.04

Estimated RMSD = 2.0±1.6Å

Download Model 2

C-score=-0.14

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3dktA	0.977	0.83	0.350	0.993
2	4pt2P	0.775	2.87	0.207	0.909
3	2e0zA	0.701	2.98	0.178	0.826
4	3bjqE	0.652	3.96	0.079	0.838
5	3bqwA	0.638	4.52	0.048	0.887
6	2fs3A	0.628	4.05	0.088	0.807
7	3jb5A	0.619	3.85	0.061	0.796
8	1yueA	0.615	4.29	0.107	0.830
9	3iyhA	0.602	4.88	0.082	0.872
10	4an5A	0.570	3.94	0.078	0.743

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.49	3	3dktA	III	Rep, Mult	1,6,20,24,34,42,229,230,231
2	0.17	3	2whxA	ADP	Rep, Mult	23,24,25,26,27,28
3	0.06	1	3enhA	TBR	Rep, Mult	154,157,161,167
4	0.06	1	3en9B	TBR	Rep, Mult	167,216,218,221
5	0.06	1	2jlsA	ADP	Rep, Mult	115,116,117,249

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2dkiA	0.377	6.32	0.049	0.641	1.14.13.23	NA
2	0.060	1l7qA	0.377	6.10	0.087	0.641	3.1.1.1	NA
3	0.060	3hmjA	0.372	6.00	0.059	0.645	2.3.1.86	NA
4	0.060	2vwbA	0.368	6.01	0.042	0.626	3.4.24.57	26
5	0.060	3e90D	0.178	6.02	0.017	0.302	3.4.21.91	261
6	0.060	1nfgA	0.407	5.31	0.066	0.619	3.5.2.2	186,187
7	0.060	1qf6A	0.376	5.55	0.045	0.589	6.1.1.3	NA
8	0.060	1gkrA	0.398	5.38	0.063	0.604	3.5.2.2	NA
9	0.060	3d64B	0.372	5.92	0.027	0.615	3.3.1.1	145,215
10	0.060	1uaaA	0.377	5.74	0.042	0.608	3.6.4.12	NA
11	0.060	1ie7C	0.397	6.22	0.050	0.672	3.5.1.5	NA
12	0.060	2bhrA	0.328	6.16	0.039	0.551	3.4.21.91	NA
13	0.060	2is4B	0.375	6.04	0.042	0.615	3.6.1.-	NA
14	0.060	2icsA	0.369	4.92	0.080	0.536	3.5.4.2	210
15	0.060	2ftwA	0.394	5.65	0.083	0.634	3.5.2.2	NA
16	0.060	2vr2A	0.379	5.95	0.086	0.634	3.5.2.2	228,229
17	0.060	3e74B	0.389	5.80	0.088	0.619	3.5.2.5	45
18	0.060	2qeqB	0.297	6.21	0.052	0.502	3.4.21.91	176
19	0.060	1kogH	0.309	6.02	0.085	0.536	6.1.1.3	116,117,119

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.62	0.977	0.83	0.35	0.99	3dktA	GO:0005576 GO:0006508 GO:0008233 GO:0016787 GO:0019835 GO:0042742
1	0.40	0.774	2.95	0.20	0.91	4pt2A	GO:0006508 GO:0008233 GO:0042742
2	0.17	0.633	3.76	0.10	0.80	3ddxA	GO:0019012 GO:0019028 GO:0019076 GO:0039620
3	0.11	0.701	2.98	0.18	0.83	2e0zA	GO:0006508 GO:0008233 GO:0016491 GO:0042742 GO:0046872 GO:0055114
4	0.08	0.652	3.85	0.08	0.83	3bjqE	GO:0019028
5	0.08	0.638	4.52	0.05	0.89	3bqwA	GO:0019028
6	0.07	0.624	4.29	0.10	0.85	1yueA	GO:0019012 GO:0019028 GO:0039621
7	0.06	0.414	2.75	0.12	0.48	3j1aG	GO:0019012 GO:0019028 GO:0019076 GO:0039620
8	0.06	0.330	6.73	0.10	0.62	2x41A	GO:0004553 GO:0005975 GO:0008152 GO:0008422 GO:0016787 GO:0016798 GO:0102483
9	0.06	0.305	5.38	0.05	0.46	3btnA	GO:0003824 GO:0005634 GO:0005737 GO:0006595 GO:0006596 GO:0033387 GO:0042177 GO:0042978 GO:0043085 GO:1902269
10	0.06	0.282	5.22	0.03	0.41	2qjjA	GO:0000287 GO:0003824 GO:0005975 GO:0008152 GO:0008927 GO:0009063 GO:0016052 GO:0016829 GO:0046872 GO:0047929
11	0.06	0.312	5.66	0.03	0.48	4n48B	GO:0003676 GO:0004483 GO:0005634 GO:0005654 GO:0005737 GO:0006370 GO:0006397 GO:0008168 GO:0016740 GO:0032259 GO:0080009 GO:0097309
12	0.06	0.311	5.98	0.04	0.52	3c0yA	GO:0000118 GO:0000122 GO:0001570 GO:0003682 GO:0003714 GO:0004407 GO:0005080 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0007043 GO:0016568 GO:0016575 GO:0016787 GO:0016925 GO:0019789 GO:0019901 GO:0030182 GO:0032041 GO:0032703 GO:0033613 GO:0045668 GO:0045892 GO:0046872 GO:0051402 GO:0070491 GO:0070932 GO:0071260 GO:0071889 GO:0090050 GO:1901215 GO:1901223
13	0.06	0.271	5.90	0.06	0.46	4gxpA	GO:0000272 GO:0004553 GO:0005975 GO:0008152 GO:0008422 GO:0016787 GO:0016798 GO:0030245 GO:0102483
14	0.06	0.246	6.05	0.06	0.42	5iw7D	GO:0000461 GO:0000462 GO:0003924 GO:0005525 GO:0005634 GO:0005730 GO:0005737 GO:0030688 GO:0034511 GO:0042254 GO:0043021
15	0.06	0.308	6.26	0.05	0.53	3c0zC	GO:0000118 GO:0000122 GO:0001570 GO:0003682 GO:0003714 GO:0004407 GO:0005080 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0007043 GO:0016568 GO:0016575 GO:0016787 GO:0016925 GO:0019789 GO:0019901 GO:0030182 GO:0032041 GO:0032703 GO:0033613 GO:0045668 GO:0045892 GO:0046872 GO:0051402 GO:0070491 GO:0070932 GO:0071260 GO:0071889 GO:0090050 GO:1901215 GO:1901223
16	0.06	0.275	6.39	0.07	0.46	5iw7B	GO:0000461 GO:0000462 GO:0003924 GO:0005525 GO:0005634 GO:0005730 GO:0005737 GO:0030688 GO:0034511 GO:0042254 GO:0043021
17	0.06	0.248	6.52	0.03	0.45	4m7xA	GO:0000166 GO:0004594 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
18	0.06	0.278	6.16	0.05	0.48	5iw7A	GO:0000461 GO:0000462 GO:0003924 GO:0005525 GO:0005634 GO:0005730 GO:0005737 GO:0030688 GO:0034511 GO:0042254 GO:0043021

Consensus prediction of GO terms

Molecular Function	GO:0008233
GO-Score	0.80
Biological Processes	GO:0042742	GO:0006508	GO:0019835	GO:0019058
GO-Score	0.80	0.80	0.62	0.34
Cellular Component	GO:0005576	GO:0019030
GO-Score	0.62	0.34

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.