I-TASSER results

I-TASSER results for job id Rv0791c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (347 residues)
MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKV
AGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHP
SVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWT
EPNPTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQV
TQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIVGTPDR
CVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Prediction	CCCCCCCEEEEEHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHCCEEHCCCCCCCCCCCEEHCCCCHHHHHHHHHHCCEEHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCEEEEEEEEEHCCCHHHHHHHHHHHHHHCCCCCEHCCHHHHHHHHHHHHHHCCCEEEEHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
Conf.Score	99989867999975778888889999999999999998997899756566778877777776655555566677777777778888886559999999999889589987555788789999999999999986995999876689888998779999998899999999999999998589855766789986857589999999997898589989999999989877679999999999999999999998999666668999999867989999999988887567875778999999999999998999999977998678999999999999999986579
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Prediction	86555301000000122423422315201400410140100000000000103434334333333334333334334444332444220100000000002203301000000100111001001000000200500010000001144004113140442630141022003002200666505150321305604131212364300000003133004100310000002113053035005203500562424264022001000013444440351154146134310000103200410450161100100000032522300320053003203531768
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCEEEEEHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHCCEEHCCCCCCCCCCCEEHCCCCHHHHHHHHHHCCEEHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCEEEEEEEEEHCCCHHHHHHHHHHHHHHCCCCCEHCCHHHHHHHHHHHHHHCCCEEEEHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP

1rhcA

0.22

0.19

0.86

2.41

MUSTER

M----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQ------------------------------SAQAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTG-EWPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSSPD-VNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

4.11

dPPAS

----MKTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQ------------------------------SAQAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTGE-WPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSSPD-VNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

4.48

wdPPAS

M----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQSA------------------------------QAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTGE-WPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSS-PDVNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

2.92

wMUSTER

-----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQSA------------------------------QAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTG-EWPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSSPD-VNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

4.07

wPPAS

M----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQSA------------------------------QAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTG-EWPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSS-PDVNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

6.08

dPPAS2

M----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQ------------------------------SAQAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTGE-WPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSSPD-VNFGIDIFKEVIPAVRD-----

1rhcA

0.22

0.19

0.86

3.47

PPAS

M----KTQIGYFAS-----LEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQ------------------------------SAQAWAWMGAALQATKKVFISTCITCPIMRNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTG-EWPSVPVRQDMTVEAVKVMRMLWESDPVTFKGDYFTLDKAFLYTKP--DDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAASTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPYMCATDAEEMIKEIERFKEAGINHFCLGNSS-PDVNFGIDIFKEVIPAVRD-----

3raoA

0.23

0.20

0.88

4.76

Env-PPAS

--YFQGVEYGFWLPIFVNDESPPTFEYAKQTAQAAEQLGFSTTLIAELNLNDIK-----------------------------GVSAPSLEAWTTAAALAAVTDRLEITAVR--PGFHN-PAVTAKAANIDQLSNGRFTLNVVSAWWEEEAKQYGGVFTAHDERYDRTEEFVTILKGLWKEEEFSYKGNFYELHHTHLSPKPVQKQGIKLYAGGESKRGKEVIVNHADAYVHGGT-VEEVSVKIEDKNRRKKVTEEPL--QSFGLAAYVICRHTEEEALEEWRRITDVKFRPNLIGTPEQIAERILAFEKVGVTLLLLQFSPQLE----EKRFSEKVPLVEAKRKEL

2b81C

0.23

0.20

0.85

2.24

MUSTER

YNAKDQLTLGVHIPIENYQFH-APTEKQVELVQKAEQYGFTGVWLRDVLLQDPDFGDP----------------------------ATGQIYDIYLTYLASKTEKIAFGTSATVLSLRHPLRVAKEIATLDQLFPERI-LGVSSGDRRADFKALGVSH---ETRGEKFREAFAYLEEILYKNFPSIQSTLGEVHGANLVPKPSK--RVPTFITGFSQQN-EWFAEHGDGWYYPR-SPVHQAGAIGQWRELVEDYHPDVFKP--FIQPHLDLSEDPNERPTPI--------RLGYRTGRKALIELLDIYKSIGVNHLFLALFDRPADEVLDELGEEVLPHFPAL----

3raoA

0.23

0.20

0.88

3.86

dPPAS

--YFQGVEYGFWLPIFVNDESPPTFEYAKQTAQAAEQLGFSTTLIAELNLNDIK-----------------------------GVSAPSLEAWTTAAALAAVTDRLEITAVR--PGFHN-PAVTAKAANIDQLSNGRFTLNVVSAWWEEEAKQYGGVFTAHDERYDRTEEFVTILKGLWKEEEFSYKGNFYELHHTHLSPKPVQKQGIKLYAGGESKRGKEVIVNHADAYVHGGT-VEEVSVKIEDKNRRKKVTEEPL--QSFGLAAYVICRHTEEEALEEWRRITDVKFRPNLIGTPEQIAERILAFEKVGVTLLLLQFSPQLEE----KRFSEKVPLVEAKRKEL

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.25

Estimated TM-score = 0.75±0.11

Estimated RMSD = 6.0±3.7Å

Download Model 2

C-score=-0.31

Download Model 3

C-score=-1.40

Download Model 4

C-score=-1.28

Download Model 5

C-score=-2.15

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1rhcA	0.829	1.48	0.214	0.862
2	3c8nA	0.781	2.06	0.238	0.844
3	3sdoA	0.774	3.16	0.185	0.893
4	3raoA	0.773	2.79	0.244	0.870
5	3b9nB	0.770	3.21	0.171	0.899
6	3fgcA	0.764	2.81	0.164	0.867
7	5dqpA	0.763	3.16	0.145	0.879
8	3fgcD	0.762	2.89	0.166	0.865
9	1yw1A	0.758	3.42	0.181	0.882
10	1ezwA	0.757	2.60	0.205	0.844

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.49	19	3b4yA	F42	Rep, Mult	46,47,48,111,112,114,143,144,145,146,149,161,213,214,215,216,217,218,219,231,233,266
2	0.08	4	1luc1	III	Rep, Mult	29,49,50,51,90,91,94,95,97,98,101,102,117,118,119,121,122,125,126,129,130,132,133,135,154,192,194,196,197,199,200,201
3	0.02	1	1rhcA	ACN	Rep, Mult	48,52,146,268
4	0.02	1	1yw1A	GLC	Rep, Mult	14,46,47,48,149
5	0.02	1	3b4yA	FLC	Rep, Mult	52,146,233,236,268,288
6	0.02	1	1ezwA	MG	Rep, Mult	100,103,104

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.384	1nqkA	0.745	2.66	0.203	0.833	1.14.14.5	145,164,169,213,217
2	0.296	1xkjA	0.758	2.89	0.176	0.862	1.14.14.3	NA
3	0.283	1f07A	0.729	2.20	0.199	0.795	1.5.99.11	112,115,117,165
4	0.242	1ezwA	0.757	2.60	0.205	0.844	1.5.99.11	213,232
5	0.180	1xbzB	0.498	3.11	0.089	0.582	4.1.1.85	123
6	0.105	1xi3A	0.461	3.34	0.110	0.545	2.5.1.3	NA
7	0.097	2v81A	0.478	3.33	0.119	0.571	4.1.2.21	NA
8	0.081	1vlwB	0.469	3.30	0.112	0.559	4.1.3.16	NA
9	0.078	1tqxA	0.497	3.54	0.106	0.594	5.1.3.1	NA
10	0.070	1tqjC	0.501	3.40	0.091	0.602	5.1.3.1	47
11	0.069	3exrA	0.501	3.23	0.098	0.591	4.1.1.85	NA
12	0.069	2fliC	0.503	3.28	0.102	0.594	5.1.3.1	NA
13	0.067	2czfA	0.483	2.87	0.109	0.553	4.1.1.23	96
14	0.067	3f4wA	0.488	3.01	0.092	0.565	4.1.2.-	NA
15	0.067	2cz5A	0.479	3.04	0.098	0.556	4.1.1.23	NA
16	0.067	3inpA	0.497	3.39	0.097	0.594	5.1.3.1	NA
17	0.067	1h1yB	0.489	3.45	0.094	0.582	5.1.3.1	264
18	0.067	1h1yA	0.487	3.43	0.089	0.582	5.1.3.1	NA
19	0.067	1v5xA	0.453	3.13	0.107	0.533	5.3.1.24	NA
20	0.066	1xi3B	0.459	3.35	0.111	0.542	2.5.1.3	143,214
21	0.060	3ii1A	0.590	3.98	0.066	0.735	3.2.1.4	NA
22	0.060	1z69C	0.744	2.20	0.209	0.813	1.5.99.11	112,213
23	0.060	1rhcA	0.829	1.48	0.214	0.862	1.1.99.5	NA
24	0.060	1tr1D	0.582	4.48	0.069	0.767	3.2.1.21	NA
25	0.060	1lucA	0.764	2.79	0.164	0.867	1.14.14.3	NA
26	0.060	1wcgA	0.581	4.39	0.067	0.755	3.2.1.147	NA
27	0.060	1itxA	0.574	5.16	0.084	0.801	3.2.1.14	NA
28	0.060	1myrA	0.577	4.63	0.043	0.775	3.2.1.147	171,215
29	0.060	1hp4A	0.584	4.39	0.086	0.767	3.2.1.52	NA
30	0.060	1reqA	0.586	4.28	0.060	0.764	5.4.99.2	22,146
31	0.060	1qoxM	0.578	4.65	0.065	0.775	3.2.1.21	99
32	0.060	3fgcA	0.764	2.81	0.164	0.867	1.14.14.3	NA
33	0.060	2bfgA	0.573	4.27	0.097	0.738	3.2.1.37	NA
34	0.060	2gftB	0.595	4.55	0.072	0.790	3.2.1.89	103,210
35	0.060	2zoxA	0.579	4.65	0.058	0.769	3.2.1.21	122,130
36	0.060	2vrkA	0.588	4.62	0.064	0.781	3.2.1.55	NA
37	0.060	2eqdA	0.577	4.04	0.071	0.729	3.2.1.151	NA
38	0.060	1r8lB	0.594	4.53	0.072	0.787	3.2.1.89	NA
39	0.060	2e3zA	0.574	4.71	0.075	0.769	3.2.1.21	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.42	0.764	2.79	0.16	0.87	1lucA	GO:0004497 GO:0008218 GO:0016491 GO:0016705 GO:0047646 GO:0055114
1	0.40	0.764	2.72	0.20	0.86	2i7gB	GO:0004497 GO:0016705 GO:0055114
2	0.40	0.791	2.77	0.24	0.89	3raoB	GO:0016705 GO:0055114
3	0.34	0.749	3.33	0.18	0.88	5aecA	GO:0004497 GO:0016491 GO:0016705 GO:0055114
4	0.33	0.829	1.48	0.21	0.86	1rhcA	GO:0016705 GO:0055114
5	0.32	0.736	3.34	0.22	0.85	2b81C	GO:0004497 GO:0005886 GO:0016491 GO:0016705 GO:0055114
6	0.31	0.801	2.06	0.23	0.86	3c8nA	GO:0004497 GO:0005618 GO:0005829 GO:0005886 GO:0005975 GO:0016491 GO:0016614 GO:0016705 GO:0045454 GO:0052749 GO:0055114 GO:0070967
7	0.31	0.729	2.20	0.20	0.80	1f07A	GO:0005737 GO:0006730 GO:0015948 GO:0016491 GO:0016705 GO:0018537 GO:0019386 GO:0055114
8	0.30	0.707	3.23	0.14	0.82	4us5C	GO:0004497 GO:0016705 GO:0055114
9	0.30	0.766	3.35	0.18	0.89	1yw1A	GO:0004497 GO:0016491 GO:0016705 GO:0055114
10	0.27	0.745	2.19	0.21	0.81	1z69A	GO:0005737 GO:0006730 GO:0015948 GO:0016491 GO:0016705 GO:0018537 GO:0019386 GO:0055114
11	0.25	0.745	2.66	0.20	0.83	1nqkA	GO:0004497 GO:0008726 GO:0009408 GO:0016491 GO:0016705 GO:0042802 GO:0046306 GO:0055114
12	0.25	0.764	2.81	0.16	0.87	3fgcA	GO:0004497 GO:0008218 GO:0016491 GO:0016705 GO:0047646 GO:0055114
13	0.25	0.767	3.34	0.19	0.89	3sdoB	GO:0004497 GO:0016491 GO:0016705 GO:0055114
14	0.21	0.774	3.16	0.18	0.89	3sdoA	GO:0004497 GO:0016491 GO:0016705 GO:0055114
15	0.19	0.770	3.21	0.17	0.90	3b9nB	GO:0000166 GO:0004497 GO:0016705 GO:0055114
16	0.15	0.763	3.16	0.14	0.88	5dqpA	GO:0004497 GO:0016705 GO:0055114
17	0.13	0.757	2.60	0.20	0.84	1ezwA	GO:0005737 GO:0006730 GO:0015948 GO:0016491 GO:0016705 GO:0018537 GO:0019386 GO:0055114
18	0.07	0.534	4.91	0.06	0.74	5bxpA	GO:0004553 GO:0004563 GO:0005975 GO:0008152 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0047403
19	0.06	0.404	6.13	0.05	0.63	4bkqA	GO:0004318 GO:0006629 GO:0006631 GO:0006633 GO:0016491 GO:0051287 GO:0055114
20	0.06	0.382	7.04	0.05	0.69	4qa0A	GO:0000118 GO:0000122 GO:0000228 GO:0004407 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0006333 GO:0006351 GO:0006355 GO:0007062 GO:0008134 GO:0016568 GO:0016575 GO:0016787 GO:0030544 GO:0031397 GO:0031647 GO:0032041 GO:0032204 GO:0046872 GO:0051879 GO:0070932 GO:0071922
21	0.06	0.583	4.27	0.09	0.76	3gh4A	GO:0004553 GO:0004563 GO:0005975
22	0.06	0.365	7.21	0.04	0.67	3sfhA	GO:0000118 GO:0000122 GO:0000228 GO:0004407 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0006333 GO:0006351 GO:0006355 GO:0007062 GO:0008134 GO:0016568 GO:0016575 GO:0016787 GO:0030544 GO:0031397 GO:0031647 GO:0032041 GO:0032204 GO:0046872 GO:0051879 GO:0070932 GO:0071922
23	0.06	0.323	5.65	0.07	0.49	2iipA	GO:0005737 GO:0005829 GO:0008112 GO:0008168 GO:0010243 GO:0016740 GO:0030760 GO:0031100 GO:0032259 GO:0042493
24	0.06	0.299	4.73	0.06	0.40	4rshA	GO:0016020 GO:0016021

Consensus prediction of GO terms

Molecular Function	GO:0047646
GO-Score	0.42
Biological Processes	GO:0055114	GO:0008218
GO-Score	0.91	0.42
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.