Threading Zmax Znorm MUSTER 5.04 0.87 dPPAS 8.53 0.92 wdPPAS 5.74 0.62 wMUSTER 3.92 0.68 wPPAS 5.42 0.77 dPPAS2 13.65 1.30 PPAS 6.93 0.99 Env-PPAS 6.24 0.78 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11034) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.69 0.40+-0.14 11.6+-4.5 4320 0.078 model2 -2.80 1839 0.070 model3 -2.21 1522 0.127 model4 -3.81 1470 0.025 model5 -3.80 1625 0.026 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).