I-TASSER results

I-TASSER results for job id Rv0776c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (259 residues)
MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPYVVGDCLVAFDAPLV
VANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFADVPRAARLARQLALDMDPLSSATR
RAIEVYPHPATVALFRLPRALKYKAKPGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQ
PDWVSLRRQVTVAQRKSDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPS
LPTDFRTAPDAGRRARARR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPYVVGDCLVAFDAPLVVANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFADVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRALKYKAKPGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRKSDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPSLPTDFRTAPDAGRRARARR
Prediction	CEEEEEHCCCCCCCCCEEEEEHCCCCEEEEHCCCCHHHHHHHHHHHCCCCCEEEHCCCCCEHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHCHCCCCCCCCCCEEEEHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHCHHHHCHHHHHHHHHHHHHHHHCCCCEEEHCCCCCCEEEEHCCCCCCCCCCCCCCCCCCCC
Conf.Score	9899997788899985899997899599986579999999999998588858997677655579888868999999987647765578888755555556999999975656766788858999868589999877654454555667658999999999999999998768766445665787766666654555554555567899999999999998688668866789878999768887787766667788899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPYVVGDCLVAFDAPLVVANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFADVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRALKYKAKPGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRKSDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPSLPTDFRTAPDAGRRARARR
Prediction	0200000001164321000001453310213303415300410362255400000210011337424130333025304535021221233343344323122015214333433465331000012200011014264325244545442542443033024204403624242414425312414452544445451452433000000000010013355412100236300000022357344444456546568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CEEEEEHCCCCCCCCCEEEEEHCCCCEEEEHCCCCHHHHHHHHHHHCCCCCEEEHCCCCCEHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHCHCCCCCCCCCCEEEEHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHCHHHHCHHHHHHHHHHHHHHHHCCCCEEEHCCCCCCEEEEHCCCCCCCCCCCCCCCCCCCC
MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPYVVGDCLVAFDAPLVVANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFADVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRALKYKAKPGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRKSDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPSLPTDFRTAPDAGRRARARR

2e2oA

0.11

0.10

0.96

0.67

MUSTER

MIIVGVDAGGTK---TKAVAYDCEGNFIGEGSSGPIENIKEAVKIAAKGEAVVGMGVAGL-----DSKFDWENFTPLASLIAPKVI-GVIALFAETLGEPGVVVIAGTGSVVEGYNGKEFLRVGGRGWAYWVGRKALRKVLKMMDGLENKTILYNKVLKTILDELVMWSYTS-SCQIDLVASIAKAVDEAANEGDTVAMDILKQGAELLASQAVYLARKIGTNKVYLKGGMFRSNIYHKFFTLYLEKEGIISDLGKRSP

4ke2A

0.13

0.10

0.76

0.54

dPPAS

--------------------MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALETINV------KAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAAATAVSAAAAAAAAAIAFAAAP-------------------------------------

4idhA2

0.14

0.10

0.74

wdPPAS

AVVSAHDPSDTGPDAKGYASRHGS-KRIAEGLLMDINEGADWATSLAIGADHYLWDG-----DGVGA--LRRQTTEAFSGKKITATMFKGSES---------------PFDEDAPYQAVRTIGDVFRNRLYLTYRAVVHGEYADPDDMLSFDKEAIGEKMLEKLFAELTQIQRKFNNNGK-------------MTKVEMKQKLNLADALMMCMH--------CPALVR---EETEIYVP--------------------

2e2oA

0.14

0.13

0.91

0.68

wMUSTER

MIIVGVDAGGTK---TKAVAYDCEGNFIGEGSSGPIENIKEAVKIAAKGEAVVGMGVA-----GLDSKFDWENFTPLASLIAPKVI--------IQHDGVIALFAETLGEPG--YNGKEFLRV--WLSAYWVGRKALRKVLKMMDGLENKTILYNKVLKTILDELVMWSYTS-SCQIDLVASIAKAVDEAANEGDTVAMDILKQGAELLASQAVYLARKIGTNKVYLKG-FRSNIYFFTLYLEKEGIISDLGKRSPE-K

4idhA2

0.14

0.10

0.73

0.92

wPPAS

AVVSAHDPSDTGPDAKGYASRHGS-KRIAEGLLMDINEGADWATSLAIGADHYLWDG-----DGVGA--LRRQTTEAFSGKKITATMFKGSES---------------PFDEDAPYQAVRTIGDVFRNYALADRLYVVHGEYADPDDMLSFDKEAIGEKMLEKLFAELTQ--IQRKFNNN-------------MTKVEMKQKLNLADALMMCM---------CPALVREET---EIYVP--------------------

4ke2A

0.13

0.10

0.76

0.87

dPPAS2

--------------------MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALETINV------KAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAAATAVSAAAAAAAAAIAFAAAP-------------------------------------

1zc6B

0.16

0.15

0.94

0.83

PPAS

IYLIGVDGGGT----TRIRLHASDGTPLAAEGGASWQAVLSTLEAAFQQAGLPAAPASACAIGLGLSGVHNRQWAGEFESQ---APGFA---RLSLATDGYTTLLGAHGGQP--ALGTGSIGEALYPDGSHREAGGWGYPSGDEASGQRAAQLTQALHSPLTRAVLDFVGGDWQAAWATPAQFARLAPLVLSAARVDPEDALLRQAGEDAWAIARALDPQDELPVALCG----GQALRDWLPPGFRQRLVAPQGDSAQR

4ep4A

0.16

0.10

0.63

1.05

Env-PPAS

MVVAGIDPGITH---LGLGVVAVEGK---------------------GALKARLLHGEVVKTSPQEPAERVGRIHARVLEVLHRFRPEAVEQFFYRQNELAYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHA-------------AKEEVALMVRGILGLKEAPRP----------------------------SHLADALAIALTHAFYARMGTAKPL--------------------------------

5cwiA

0.09

0.08

0.90

0.66

MUSTER

---------------------DIEKLCKKAESAREARSKAEELRQRHPDSQAARDAQKLA----SQAEEAVKLACELAQEHPNADIAKLCIKAASEAAEAASKAAELAQRHPDSQAARDAIKLASQAAEAVKLACELAQEHPNADIAKLCIKAASEAAEAASKAAELAQRHPDSQAARDAIKLASQAAEAVKLACELAQEHPNADIAKKCIKAASEAAEEASKAAEEAQRHPDSQKARDEIKEASQKAEEVKERCER--

5cwiA

0.13

0.12

0.87

0.53

dPPAS

----------------------DIEKLCKKAESEAREARSKAEELRQRHPDSQAARDAQKLASQA---EEAVKLACELAQEHPNADIAKLCIKAASEAAEAASKAAELAQRHPDSQAARDAIKLASQAAEAVKLACELAQEHPNADIAKLCIKAASEAAEAASKAAELAQRHPDSQAARDAIKLASQAAEAVKLACELAQEHPNADIAKKCIKAASEAAEEASKAAEE---------AQRHPDSQKARDEIKEASQKAE

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.85

Estimated TM-score = 0.49±0.15

Estimated RMSD = 10.1±4.6Å

Download Model 2

C-score=-4.44

Download Model 3

C-score=-4.37

Download Model 4

C-score=-5.00

Download Model 5

C-score=-4.23

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2e2oA	0.831	2.21	0.112	0.930
2	2ch5A	0.756	3.17	0.086	0.938
3	1zbsA	0.719	3.06	0.107	0.869
4	1zxoB	0.712	3.27	0.109	0.884
5	1zc6B	0.701	3.43	0.126	0.892
6	4qs7A	0.700	3.56	0.078	0.880
7	3imxA	0.699	3.52	0.069	0.880
8	1dgkN2	0.694	3.57	0.061	0.880
9	1bdgA	0.691	3.49	0.057	0.873
10	3hm8A	0.691	3.56	0.065	0.873

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.24	13	3hm9A	MG	Rep, Mult	7,56
2	0.04	2	1hkbA	CA	Rep, Mult	207,210,212,214
3	0.04	2	2e2qA	ADP	Rep, Mult	9,11,14,15,17,181,182,184,185,188,229,231,233,235
4	0.04	2	4dlmA	ZN	Rep, Mult	207,259
5	0.04	2	1k9yA	MG	Rep, Mult	124,204,206,207
6	0.02	1	1zc60	III	Rep, Mult	191,193,194,199,203,207,210,214,239,242,243,244
7	0.02	1	1qgxA	MG	Rep, Mult	92,124
8	0.02	1	3imxA	NA	Rep, Mult	61,64,65,66
9	0.02	1	2ch6D	GLC	Rep, Mult	9,14,17,33
10	0.02	1	2wc9A	MN	Rep, Mult	7,128

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.145	2e2oA	0.831	2.21	0.112	0.930	2.7.1.1	NA
2	0.066	1woqA	0.541	3.60	0.093	0.703	2.7.1.63	NA
3	0.066	3bf3A	0.543	4.12	0.078	0.745	2.7.1.33	7,100,229
4	0.066	3eo3A	0.575	4.19	0.107	0.795	5.1.3.14,2.7.1.60	NA
5	0.066	2f9wA	0.531	4.19	0.120	0.741	2.7.1.33	7,229
6	0.066	1q18A	0.567	4.56	0.108	0.819	2.7.1.2	NA
7	0.060	2iirJ	0.589	4.36	0.056	0.811	2.7.2.1	129
8	0.060	2ewsA	0.583	3.41	0.089	0.738	2.7.1.33	7,255
9	0.060	2aa4A	0.594	4.10	0.136	0.819	2.7.1.60	NA
10	0.060	2e20A	0.577	4.78	0.053	0.834	2.7.2.15	NA
11	0.060	1ig8A	0.612	4.62	0.078	0.861	2.7.1.1	NA
12	0.060	3f9mA	0.703	3.51	0.074	0.884	2.7.1.2	NA
13	0.060	2ivpA	0.580	3.93	0.123	0.784	3.4.24.57	9,181
14	0.060	2ch5A	0.756	3.17	0.086	0.938	2.7.1.59	12,128
15	0.060	3en9A	0.591	3.77	0.137	0.788	3.4.24.57	59
16	0.060	2uytA	0.606	4.07	0.080	0.819	2.7.1.5	9
17	0.060	2d4wA	0.601	4.18	0.080	0.822	2.7.1.30	7
18	0.060	1hkgA	0.667	3.89	0.100	0.876	2.7.1.1	234
19	0.060	1zc6B	0.701	3.43	0.126	0.892	2.7.1.59	7,12
20	0.060	2aa4B	0.592	4.15	0.136	0.819	2.7.1.60	12
21	0.060	3flcX	0.631	3.95	0.060	0.838	2.7.1.30	209
22	0.060	2iirA	0.586	4.50	0.050	0.826	2.7.2.1	NA
23	0.060	3b8aX	0.677	3.64	0.091	0.873	2.7.1.1	NA
24	0.060	3hz6A	0.578	4.47	0.079	0.830	2.7.1.17	37
25	0.060	1bdgA	0.691	3.49	0.057	0.873	2.7.1.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.18	0.831	2.21	0.11	0.93	2e2oA	GO:0000166 GO:0004396 GO:0016301 GO:0016310 GO:0016740 GO:0046835
1	0.14	0.756	3.17	0.09	0.94	2ch5A	GO:0000166 GO:0005524 GO:0005829 GO:0006044 GO:0006048 GO:0006051 GO:0009384 GO:0016301 GO:0016310 GO:0016740 GO:0019262 GO:0045127 GO:0046835 GO:0070062
2	0.13	0.713	3.26	0.12	0.89	1zc6B	GO:0016301 GO:0016310 GO:0016740 GO:0045127 GO:0046835
3	0.07	0.550	4.47	0.10	0.78	4o5fA	GO:0000166 GO:0004594 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
4	0.07	0.575	4.19	0.11	0.80	3eo3A	GO:0000166 GO:0003824 GO:0004553 GO:0005524 GO:0005737 GO:0005829 GO:0006045 GO:0006047 GO:0006054 GO:0007155 GO:0008152 GO:0008761 GO:0009384 GO:0016301 GO:0016310 GO:0016740 GO:0016787 GO:0046835 GO:0046872
5	0.07	0.551	4.40	0.12	0.77	5b8hA	GO:0000166 GO:0004594 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
6	0.06	0.382	6.20	0.08	0.67	4gpaA	GO:0004872 GO:0004970 GO:0004971 GO:0005216 GO:0005234 GO:0005886 GO:0006810 GO:0006811 GO:0007268 GO:0008328 GO:0014069 GO:0016020 GO:0016021 GO:0030054 GO:0030425 GO:0032281 GO:0032983 GO:0034220 GO:0035235 GO:0042995 GO:0043025 GO:0043195 GO:0045202 GO:0045211 GO:0050803 GO:0050804 GO:0051968 GO:0060992
7	0.06	0.340	6.08	0.04	0.59	1bhwA	GO:0000287 GO:0005737 GO:0005975 GO:0006098 GO:0009045 GO:0016853 GO:0042732 GO:0046872
8	0.06	0.346	6.03	0.06	0.59	2akzA	GO:0000015 GO:0000287 GO:0001917 GO:0004634 GO:0005615 GO:0005622 GO:0005737 GO:0005829 GO:0005886 GO:0006094 GO:0006096 GO:0016020 GO:0016829 GO:0043025 GO:0043204 GO:0043209 GO:0046872 GO:0061621 GO:0070062
9	0.06	0.294	6.19	0.06	0.51	2iveA	GO:0004729 GO:0005737 GO:0006779 GO:0006782 GO:0006783 GO:0016020 GO:0016491 GO:0055114
10	0.06	0.302	5.78	0.09	0.51	2p30A	GO:0003824 GO:0008152
11	0.06	0.321	5.94	0.06	0.54	3k53D	GO:0005525 GO:0015093 GO:0015684 GO:0016020 GO:0016021 GO:1903874
12	0.06	0.280	5.68	0.09	0.46	2wjgA	GO:0000166 GO:0003924 GO:0005525 GO:0005737 GO:0005886 GO:0006810 GO:0006811 GO:0015093 GO:0015684 GO:0016020 GO:0016021 GO:0055072 GO:1903874
13	0.06	0.331	5.93	0.06	0.57	3jcrV	GO:0000245 GO:0000398 GO:0005634 GO:0005654 GO:0005681 GO:0006397 GO:0007049 GO:0008270 GO:0008380 GO:0016579 GO:0036459 GO:0046872 GO:0051301
14	0.06	0.289	5.74	0.06	0.47	2gs9A	GO:0008152 GO:0008168 GO:0032259
15	0.06	0.328	5.67	0.05	0.54	1tiaA	GO:0006629 GO:0016042 GO:0016787
16	0.06	0.266	4.86	0.02	0.39	3w5iB	GO:0005525 GO:0005886 GO:0006810 GO:0015093 GO:0015684 GO:0016020 GO:0016021 GO:0055072 GO:1903874
17	0.06	0.267	5.02	0.04	0.41	3e2iA	GO:0000166 GO:0004797 GO:0005524 GO:0005737 GO:0006259 GO:0008270 GO:0009157 GO:0016301 GO:0016310 GO:0016740 GO:0046872 GO:0071897
18	0.06	0.249	4.56	0.06	0.35	4zhvA	GO:0009279 GO:0016020 GO:0016021

Consensus prediction of GO terms

Molecular Function	GO:0032559	GO:0035639	GO:0032550	GO:0019200	GO:0016773
GO-Score	0.50	0.50	0.50	0.50	0.40
Biological Processes	GO:0046835
GO-Score	0.42
Cellular Component	GO:0044444
GO-Score	0.40

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.