I-TASSER results

Input Sequence in FASTA format

>protein (182 residues)
MDPLMAHQRAQDAFAALLANVRADQLGGPTPCSEWTINDLIEHVVGGNEQVGRWAASPIE
PPARPDGLVAAHQAAAAVAHEIFAAPGGMSATFKLPLGEVPGQVFIGLRTTDVLTHAWDL
AAATGQSTDLDPELAVERLAAARALVGPQFRGPGKPFADEKPCPRERPPADQLAAFLGRT
VR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MDPLMAHQRAQDAFAALLANVRADQLGGPTPCSEWTINDLIEHVVGGNEQVGRWAASPIEPPARPDGLVAAHQAAAAVAHEIFAAPGGMSATFKLPLGEVPGQVFIGLRTTDVLTHAWDLAAATGQSTDLDPELAVERLAAARALVGPQFRGPGKPFADEKPCPRERPPADQLAAFLGRTVR
Prediction	CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
Conf.Score	98999999999999999984998886899999999999999999888888998765677888888757888999999999998777776566767888888999999999899999878777768999999999999999999856656545678777766899999899999998789999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MDPLMAHQRAQDAFAALLANVRADQLGGPTPCSEWTINDLIEHVVGGNEQVGRWAASPIEPPARPDGLVAAHQAAAAVAHEIFAAPGGMSATFKLPLGEVPGQVFIGLRTTDVLTHAWDLAAATGQSTDLDPELAVERLAAARALVGPQFRGPGKPFADEKPCPRERPPADQLAAFLGRTVR
Prediction	75425203401420241055045731732130653302230101031133023113443534332522142034004302401544542433243341422022003110110000010002024353613450033004103622464234462212461414771421120002142448
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
MDPLMAHQRAQDAFAALLANVRADQLGGPTPCSEWTINDLIEHVVGGNEQVGRWAASPIEPPARPDGLVAAHQAAAAVAHEIFAAPGGMSATFKLPLGEVPGQVFIGLRTTDVLTHAWDLAAATGQSTDLDPELAVERLAAARALVGPQFRGPGKPFADEKPCPRERPPADQLAAFLGRTVR

2nsgA

0.19

0.99

1.33

MUSTER

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGLVLSTRYPAAPGQSLAGIVRYAAGRGSD

2nsgA

0.18

0.99

1.17

dPPAS

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHWANTGEETPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGPAAPGQDEVVVSGSLAGIVRYAAGRGSD

2nsgA

0.19

0.99

2.42

wdPPAS

MERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGPAAPGQDEVVVSGSLAGIVRYAAGRGSD

2nsgA

0.20

0.99

1.65

wMUSTER

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGYPAAPGQDEV-SGSLAGIVRYAAGRGSD

2nsgA

0.21

0.98

2.61

wPPAS

MERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGAPGQDEVVV--SGSLAGIVRYAAGRGSD

2nsgA

0.19

0.99

3.13

dPPAS2

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGPAAPGQDEVVVSGSLAGIVRYAAGRGSD

2nsgA

0.19

0.99

1.79

PPAS

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGPAAPGQDEVVVSGSLAGIVRYAAGRGSD

2nsgA

0.18

0.99

2.29

Env-PPAS

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHWANTGTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLGAVATFG-DIPEVILRTLAAEITQKWTSQGAGEGPAAPGQDEVVVSGSLAGIVRYAAGRGSD

2nsgA1

0.21

0.14

0.68

0.97

MUSTER

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHGEETPTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRVPASETLWMRSREVWIHAVDLG-AVA---------------------------------------------------------

2nsgA1

0.19

0.13

0.68

0.90

dPPAS

EERLTLARLGTSHYSRQLSLVDNAEFGEHSLLEGWTRSHLIAAVAYNAIALCNLMHWANTGTLNPDALRNLHEHSVARLDVAWRETSEWSHEVLTAQGRTPASETLWMRSREVWIHAVDLGAVA----------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.52

Estimated TM-score = 0.78±0.09

Estimated RMSD = 4.1±2.8Å

Download Model 2

C-score=-4.90

Download Model 3

C-score=-5.00

Download Model 4

C-score=-5.00

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2nsgA	0.933	1.86	0.171	0.989
2	4x8bA	0.592	4.22	0.071	0.813
3	3dkaB	0.568	2.81	0.095	0.687
4	3gorA	0.562	2.85	0.102	0.687
5	2qnlA	0.557	2.54	0.124	0.643
6	2f22A	0.553	2.78	0.107	0.659
7	3di5A	0.548	2.93	0.106	0.670
8	2qe9A	0.544	3.07	0.060	0.681
9	2yqyA	0.542	2.67	0.197	0.637
10	5cogA	0.537	3.34	0.085	0.670

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.63	9	2nsfA	ZN	Rep, Mult	43,112,116
2	0.05	1	3qnqA	ZDM	Rep, Mult	19,112,113,116,121

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1kblA	0.429	5.41	0.057	0.736	2.7.9.1	NA
2	0.060	1fbvA	0.432	3.83	0.054	0.588	6.3.2.19	NA
3	0.060	1ra0A	0.412	5.42	0.052	0.742	3.5.4.1	NA
4	0.060	1is2A	0.420	4.58	0.053	0.654	1.3.3.6	NA
5	0.060	1n1hA	0.422	4.78	0.040	0.659	2.7.7.48	12
6	0.060	2ix4A	0.325	5.49	0.054	0.577	2.3.1.41	NA
7	0.060	1kc7A	0.424	5.57	0.043	0.747	2.7.9.1	132
8	0.060	3b7wA	0.423	5.29	0.052	0.736	6.2.1.2	NA
9	0.060	1ua4A	0.427	5.22	0.068	0.725	2.7.1.147	43,75
10	0.060	1qi9B	0.426	5.51	0.041	0.753	1.11.1.10	43,116
11	0.060	2z8yP	0.448	4.11	0.094	0.670	2.3.1.169	14
12	0.060	2z8yD	0.439	5.37	0.063	0.725	1.2.7.4,1.2.99.2	128
13	0.060	2jkpB	0.438	5.45	0.054	0.769	3.2.1.20	NA
14	0.060	1w0iA	0.426	5.40	0.084	0.753	2.3.1.41	NA
15	0.060	1pz2A	0.419	5.47	0.058	0.742	3.2.1.55	10
16	0.060	2fonB	0.385	5.55	0.058	0.692	1.3.3.6	NA
17	0.060	1jqkF	0.491	4.58	0.065	0.736	1.2.99.2	114
18	0.060	3djlA	0.469	5.07	0.048	0.780	1.3.99.-	NA
19	0.060	1jdaA	0.335	5.24	0.046	0.577	3.2.1.60	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.39	0.931	1.89	0.18	0.99	2nsfA	GO:0046872
1	0.07	0.592	4.22	0.07	0.81	4x8bA	GO:0004497 GO:0005506 GO:0016491 GO:0016705 GO:0046872 GO:0052699 GO:0055114
2	0.07	0.575	2.88	0.09	0.70	3dkaB	GO:0046872
3	0.06	0.369	4.24	0.08	0.54	4xevA	GO:0000165 GO:0000166 GO:0000302 GO:0001525 GO:0001556 GO:0001666 GO:0001954 GO:0002040 GO:0002250 GO:0002315 GO:0002376 GO:0002688 GO:0004672 GO:0004683 GO:0004713 GO:0004715 GO:0004871 GO:0004972 GO:0005102 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0005938 GO:0006461 GO:0006468 GO:0006915 GO:0006950 GO:0006968 GO:0006970 GO:0007015 GO:0007155 GO:0007165 GO:0007166 GO:0007172 GO:0007173 GO:0007204 GO:0007229 GO:0008284 GO:0008285 GO:0008360 GO:0009612 GO:0009725 GO:0009749 GO:0010226 GO:0010243 GO:0010595 GO:0010656 GO:0010752 GO:0010758 GO:0010976 GO:0014009 GO:0014069 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0017146 GO:0018108 GO:0030027 GO:0030054 GO:0030154 GO:0030155 GO:0030279 GO:0030307 GO:0030334 GO:0030335 GO:0030424 GO:0030425 GO:0030426 GO:0030500 GO:0030502 GO:0030826 GO:0030838 GO:0031175 GO:0031234 GO:0032270 GO:0032403 GO:0032960 GO:0033209 GO:0035235 GO:0035902 GO:0038083 GO:0042127 GO:0042220 GO:0042493 GO:0042542 GO:0042976 GO:0042995 GO:0043025 GO:0043066 GO:0043149 GO:0043267 GO:0043423 GO:0043507 GO:0043524 GO:0043534 GO:0043552 GO:0044297 GO:0045087 GO:0045121 GO:0045428 GO:0045429 GO:0045453 GO:0045471 GO:0045638 GO:0045727 GO:0045765 GO:0045766 GO:0045860 GO:0046330 GO:0046777 GO:0048010 GO:0048041 GO:0048471 GO:0050731 GO:0050848 GO:0051000 GO:0051279 GO:0051591 GO:0051592 GO:0051968 GO:0060291 GO:0060292 GO:0070098 GO:0070374 GO:0071300 GO:0071498 GO:0090630 GO:0097440 GO:2000058 GO:2000060 GO:2000114 GO:2000249 GO:2000310 GO:2000379 GO:2000463 GO:2000538 GO:2000573
4	0.06	0.351	5.74	0.10	0.65	2x7gA	GO:0000166 GO:0000245 GO:0000287 GO:0001525 GO:0004672 GO:0004674 GO:0005524 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0006397 GO:0006468 GO:0008284 GO:0008380 GO:0010628 GO:0016301 GO:0016310 GO:0016740 GO:0030154 GO:0035063 GO:0035556 GO:0043525 GO:0044822 GO:0045070 GO:0045071 GO:0045087 GO:0045787 GO:0048024 GO:0071889
5	0.06	0.367	5.27	0.04	0.60	3fwnA	GO:0004616 GO:0005829 GO:0006098 GO:0016491 GO:0019521 GO:0042802 GO:0042803 GO:0055114
6	0.06	0.332	5.73	0.06	0.60	4kyoC	GO:0003824 GO:0004760 GO:0005102 GO:0005739 GO:0005759 GO:0005777 GO:0005782 GO:0007219 GO:0008453 GO:0008483 GO:0009436 GO:0010498 GO:0016597 GO:0016740 GO:0019265 GO:0019448 GO:0030170 GO:0042803 GO:0042853 GO:0042866 GO:0043621 GO:0046487 GO:0046724 GO:0051384 GO:0051591
7	0.06	0.335	5.79	0.06	0.60	1y1hX	GO:0005783 GO:0005788 GO:0006687 GO:0016491 GO:0042803 GO:0043687 GO:0046872 GO:0055114
8	0.06	0.289	6.11	0.04	0.56	2y3cA	GO:0046872
9	0.06	0.328	5.47	0.03	0.54	3b8gA	GO:0004042 GO:0005737 GO:0006526 GO:0008080 GO:0008652 GO:0016740 GO:0016746
10	0.06	0.306	5.45	0.04	0.53	4gh8A	GO:0004146 GO:0005829 GO:0006545 GO:0006730 GO:0009165 GO:0016491 GO:0031427 GO:0042493 GO:0046654 GO:0046677 GO:0050661 GO:0055114
11	0.06	0.312	5.45	0.05	0.57	1y4jB	GO:0005783 GO:0005788 GO:0043687 GO:0046872
12	0.06	0.359	5.89	0.07	0.69	1kfqA	GO:0000287 GO:0004614 GO:0005737 GO:0005975 GO:0016853 GO:0016868 GO:0046872 GO:0071704
13	0.06	0.341	5.64	0.07	0.63	5dn1A	GO:0000105 GO:0000162 GO:0003824 GO:0003949 GO:0004640 GO:0005622 GO:0005737 GO:0008152 GO:0008652 GO:0009073 GO:0016853
14	0.06	0.344	5.57	0.06	0.61	3amgB	GO:0004553 GO:0005576 GO:0005975 GO:0006073 GO:0008152 GO:0008422 GO:0009251 GO:0009986 GO:0016787 GO:0016798
15	0.06	0.239	5.40	0.06	0.40	4wp5A	GO:0005634 GO:0051028
16	0.06	0.288	5.99	0.03	0.56	2q17E	GO:0046872
17	0.06	0.285	5.16	0.08	0.47	4meeA	GO:0005576 GO:0007155 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0019867 GO:0042597
18	0.06	0.251	5.89	0.06	0.48	4qzvB	GO:0009405 GO:0016020 GO:0016021 GO:0016032 GO:0019012 GO:0019031 GO:0019062 GO:0033644 GO:0039663 GO:0044173 GO:0046718 GO:0046813 GO:0055036 GO:0061025

Consensus prediction of GO terms

Molecular Function	GO:0046872
GO-Score	0.47
Biological Processes	GO:0008284	GO:0045087	GO:0052699	GO:0055114	GO:0000245	GO:0010226	GO:0008360	GO:0007229	GO:0001556	GO:0045787	GO:0032960	GO:0030838	GO:2000573	GO:0043552	GO:0007173	GO:0070374	GO:0001954	GO:2000538	GO:0050848	GO:0042542	GO:0071300	GO:0048010	GO:0010595	GO:0071498	GO:0050731	GO:0045766	GO:0048041	GO:0045471	GO:0009725	GO:0043524	GO:0043507	GO:0030502	GO:0002040	GO:0060291	GO:2000249	GO:2000114	GO:0035063	GO:0006970	GO:0045453	GO:0042220	GO:0010758	GO:0002315	GO:0009749	GO:0008285	GO:0045638	GO:0007172	GO:0090630	GO:0014009	GO:2000060	GO:0001666	GO:0043525	GO:0060292	GO:0035235	GO:0002250	GO:0038083	GO:0045070	GO:2000463	GO:0010752	GO:0045071	GO:0030826	GO:0051591	GO:0043534	GO:0033209	GO:2000310	GO:0006968	GO:0042493	GO:0010656	GO:0010976	GO:0048024	GO:0043149	GO:0051000	GO:0043267	GO:0051592	GO:0042976	GO:0070098	GO:0051968	GO:0051279	GO:0045727	GO:0045429	GO:0009612	GO:0030307	GO:0035902
GO-Score	0.12	0.12	0.07	0.07	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Cellular Component	GO:0005654	GO:0045121	GO:0030027	GO:0030424	GO:0031234	GO:0005829	GO:0043025	GO:0048471	GO:0005856	GO:0005730	GO:0014069	GO:0005938	GO:0005925	GO:0017146	GO:0097440	GO:0030426
GO-Score	0.12	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0738

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]