Threading Zmax Znorm MUSTER 4.97 0.86 dPPAS 16.88 1.82 wdPPAS 13.50 1.45 wMUSTER 5.79 1.00 wPPAS 8.77 1.25 dPPAS2 69.09 6.58 PPAS 8.41 1.20 Env-PPAS 9.06 1.13 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 0.39 0.77+-0.10 3.4+-2.4 14040 0.772 model2 -4.06 254 0.009 model3 -3.54 189 0.015 model4 -4.49 177 0.006 model5 -3.98 122 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).