Threading Zmax Znorm MUSTER 4.99 0.86 dPPAS 8.92 0.96 wdPPAS 8.12 0.87 wMUSTER 5.36 0.92 wPPAS 7.24 1.03 dPPAS2 20.24 1.93 PPAS 8.88 1.27 Env-PPAS 5.17 0.65 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.62 0.32+-0.11 15.5+-3.3 2138 0.025 model2 -4.07 1233 0.016 model3 -4.44 948 0.011 model4 -4.42 928 0.011 model5 -5.00 369 0.005 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).