Threading Zmax Znorm MUSTER 7.31 1.26 dPPAS 9.85 1.06 wdPPAS 8.40 0.90 wMUSTER 7.60 1.31 wPPAS 7.57 1.08 dPPAS2 13.59 1.29 PPAS 10.43 1.49 Env-PPAS 10.02 1.25 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=1506) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.28 0.68+-0.12 9.0+-4.6 753 0.625 model2 -2.85 328 0.048 model3 -2.20 111 0.092 model4 -2.28 102 0.085 model5 -2.33 97 0.081 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).