Threading Zmax Znorm MUSTER 4.38 0.76 dPPAS 6.14 0.66 wdPPAS 5.80 0.62 wMUSTER 3.90 0.67 wPPAS 4.46 0.64 dPPAS2 11.32 1.08 PPAS 4.79 0.68 Env-PPAS 5.19 0.65 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.59 0.24+-0.07 16.2+-3.1 1821 0.014 model2 -4.79 1609 0.012 model3 -4.38 1471 0.017 model4 -5.00 1090 0.008 model5 -5.00 1025 0.008 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).