Threading Zmax Znorm MUSTER 7.25 1.25 dPPAS 10.93 1.18 wdPPAS 16.53 1.78 wMUSTER 9.14 1.58 wPPAS 16.58 2.37 dPPAS2 22.18 2.11 PPAS 12.21 1.74 Env-PPAS 12.38 1.55 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=7530) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.88 0.39+-0.13 14.2+-3.8 1414 0.033 model2 -3.15 1035 0.025 model3 -3.43 769 0.019 model4 -3.91 436 0.012 model5 -3.96 497 0.011 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).