Threading Zmax Znorm MUSTER 6.33 1.09 dPPAS 9.19 0.99 wdPPAS 9.63 1.04 wMUSTER 7.30 1.26 wPPAS 6.10 0.87 dPPAS2 13.54 1.29 PPAS 7.21 1.03 Env-PPAS 10.45 1.31 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4008) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.68 0.51+-0.15 6.1+-3.8 2505 0.168 model2 -2.23 1379 0.097 model3 -4.82 143 0.007 model4 -5.00 95 0.005 model5 -1.64 2405 0.174 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).