I-TASSER results

Input Sequence in FASTA format

>protein (202 residues)
MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQ
RAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWG
EPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALAS
VTSLIYDGDRLVDVVYSQPAAL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQRAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWGEPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALASVTSLIYDGDRLVDVVYSQPAAL
Prediction	CCCCEEEEEEHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHCCCHHHHHHHHHHHHHHCCCEEHCCCCHHHCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEHCCEEEEEEHCCCCCC
Conf.Score	9998599999667655667755688999989989999999999999789998999789599999999999998998688787555479877889999998785878887598899999999999999999999999999889996999968599999999999999777666658887668999998999999997576789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQRAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWGEPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALASVTSLIYDGDRLVDVVYSQPAAL
Prediction	8475045121224304245312002144265354234045302620573604234044342032003100752704032375324313304434164046415524414534551304401214201510250042017516743000001110000000201613144234426040000010204663011011023136
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCEEEEEEHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHCCCHHHHHHHHHHHHHHCCCEEHCCCCHHHCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEHCCEEEEEEHCCCCCC
MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQRAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWGEPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALASVTSLIYDGDRLVDVVYSQPAAL

4ij5A

0.26

0.98

4.03

MUSTER

M---VKLILVRHAESWNPVGRYQGL-LDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWS-FGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.26

0.98

7.71

dPPAS

---MVKLILVRHAESWNPVGRYQGLL-DPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKF-WSFGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.25

0.98

6.51

wdPPAS

M---VKLILVRHAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKF-WSFGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.25

0.24

0.98

4.58

wMUSTER

----VKLILVRHAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWS-FGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.25

0.98

4.65

wPPAS

M---VKLILVRHAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKF-WSFGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.27

0.26

0.98

7.70

dPPAS2

M---VKLILVRHAESWNPVGRYQGLL-DPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKF-WSFGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.27

0.26

0.98

4.26

PPAS

M---VKLILVRHAESWNPVGRYQGLL-DPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWS-FGCDNASYSVIHMEERRNVILKLNITCHL

4ij5A

0.27

0.26

0.98

5.99

Env-PPAS

M---VKLILVRHAESWNPVGRYQGLL-DPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEDHGMWSGMLVEEVMEKYPEFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWS-FGCDNASYSVIHMEERRNVILKLNITCHL

1h2fA

0.24

0.23

0.98

3.97

MUSTER

---ATTLYLTRHGETWNVERRMQGW-QDSPLTEKGRQDAMRLGKRLEAVELAAIYTSTSGRALETAEIVRGGRLIPIYQDERLREHLGDWEGKTHDEIRQMDPIFDHFWQAPHLYAPQRGERFCDVQQRALEAVQSIVDRHEGETVLIVTHGVVLKTLMAAFKDTPLDHLWSPPYMYGTSVTIIEVDGGTFHVAVEGDVSHI

1h2fA

0.24

0.23

0.98

7.57

dPPAS

---ATTLYLTRHGETWNVERRMQGWQ-DSPLTEKGRQDAMRLGKRLEAVELAAIYTSTSGRALETAEIVRGGRLIPIYQDERLREHLGDWEGKTHDEIRQMDPIFDHFWQAPHLYAPQRGERFCDVQQRALEAVQSIVDRHEGETVLIVTHGVVLKTLMAAFKDTPLDHLWSPPYMYGTSVTIIEVDGGTFHVAVEGDVSHI

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 1 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=1.76

Estimated TM-score = 0.96±0.05

Estimated RMSD = 2.0±1.6Å

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4ij5A	0.957	0.88	0.242	0.980
2	1h2fA	0.904	1.71	0.221	0.985
3	4pz9A	0.883	1.79	0.255	0.970
4	2hhjA	0.859	2.32	0.173	0.975
5	3gp5A	0.858	2.21	0.163	0.970
6	3e9dA	0.852	2.49	0.237	0.965
7	1riiA	0.852	2.44	0.186	0.980
8	3hjgA	0.848	2.23	0.173	0.970
9	2a6pA	0.848	1.94	0.200	0.941
10	1xq9A	0.848	2.54	0.156	0.985

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.50	62	3o0tB	PO4	Rep, Mult	11,12,15,61,85,151,152
2	0.11	22	1tipA	F6P	Rep, Mult	23,24,95,108,112,123,152,156
3	0.09	15	3ll4A	2FP	Rep, Mult	11,18,23,24,61,87,151,152,153,156
4	0.05	15	3gw8A	VO4	Rep, Mult	23,87,95,153
5	0.04	9	1riiB	GOL	Rep, Mult	12,15,18,24,61,151
6	0.03	7	5ajvB	FDP	Rep, Mult	11,12,18,23,24,95,108,112,123,151,152,156
7	0.03	9	3fdzB	3PG	Rep, Mult	12,22,23,24,25,87,95,153
8	0.03	6	1qhfA	3PG	Rep, Mult	11,12,13,14,15,18,24,61,178
9	0.03	9	3qpvA	ADP	Rep, Mult	1,189
10	0.02	3	1h2fA	PO4	Rep, Mult	4,5,6,143,144,145
11	0.02	5	1bq3A	IHP	Rep, Mult	11,12,14,15,17,18,23,24,87,95,175
12	0.01	2	5pgmB	SO4	Rep, Mult	22,87,95,110
13	0.01	2	1c7zA	G3H	Rep, Mult	112,123,152,153,156
14	0.00	1	1riiD	GOL	Rep, Mult	55,78,137
15	0.00	1	3d6aA	MG	Rep, Mult	94,95
16	0.00	1	3d6aA	MG	Rep, Mult	122,123
17	0.00	1	1yfkA	CL	Rep, Mult	67,77,79

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.549	2h4xA	0.863	2.33	0.177	0.980	3.1.3.13,5.4.2.4,5.4.2.1	12,61,85,151
2	0.541	1riiA	0.852	2.44	0.186	0.980	5.4.2.1	12,61,85,151
3	0.529	1qhfA	0.838	2.39	0.179	0.965	5.4.2.1	12,61,85,151
4	0.506	1fztA	0.846	2.37	0.208	0.975	5.4.2.1	12,61,151
5	0.470	3eozA	0.599	2.89	0.181	0.703	5.4.2.1	61,85,151
6	0.433	3gp5A	0.858	2.21	0.163	0.970	5.4.2.1	12,61,151
7	0.408	1yjxA	0.845	2.43	0.152	0.980	3.1.3.13,5.4.2.1,5.4.2.4	12,61,151
8	0.209	3e9cA	0.693	2.27	0.259	0.767	3.1.3.46	61,85,151
9	0.060	2a6pA	0.848	1.94	0.200	0.941	5.4.2.1	12,61,151
10	0.060	2wnhA	0.638	4.13	0.167	0.876	3.1.3.8	44
11	0.060	1dkmA	0.632	3.99	0.143	0.856	3.1.3.26,3.1.3.2	11,12,61,151
12	0.060	1e19A	0.499	5.03	0.082	0.772	2.7.2.2	NA
13	0.060	1nt4A	0.648	4.10	0.133	0.871	3.1.3.10	132,138
14	0.060	3it3A	0.627	4.04	0.108	0.852	3.1.3.2	11,179
15	0.060	1nd6B	0.630	4.35	0.119	0.886	3.1.3.2	11,12,61,151
16	0.060	3eozB	0.598	3.37	0.162	0.757	5.4.2.1	62
17	0.060	1qfxB	0.613	4.23	0.120	0.852	3.1.3.8	11,12,61
18	0.060	1alkA	0.503	5.04	0.094	0.782	3.1.3.1	NA
19	0.060	2p30A	0.758	2.28	0.192	0.852	3.1.3.73	11,22
20	0.060	1e58A	0.847	2.37	0.184	0.970	5.4.2.1	NA
21	0.060	1c7zA	0.829	1.97	0.209	0.926	2.7.1.105,3.1.3.46	11,12,61,85,151
22	0.060	2hhjA	0.859	2.32	0.173	0.975	3.1.3.13,5.4.2.1,5.4.2.4	13
23	0.060	1ihpA	0.634	4.38	0.067	0.886	3.1.3.8	11,12,61,151
24	0.060	3e9dA	0.852	2.49	0.237	0.965	3.1.3.46	12,61,151
25	0.060	2gfiA	0.614	4.42	0.122	0.871	3.1.3.8	NA
26	0.060	2bifA	0.841	1.93	0.189	0.941	3.1.3.46,2.7.1.105	133,141,155

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.49	0.858	2.21	0.16	0.97	3gp5A	GO:0003824 GO:0004619 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0046538
1	0.48	0.852	2.49	0.24	0.97	3e9dA	GO:0003824 GO:0004083 GO:0004331 GO:0005634 GO:0005737 GO:0005739 GO:0005741 GO:0005829 GO:0006003 GO:0006914 GO:0006915 GO:0008152 GO:0016311 GO:0016787 GO:0030388
2	0.47	0.845	1.90	0.20	0.94	1k6mA	GO:0000166 GO:0003824 GO:0003873 GO:0004331 GO:0005524 GO:0005829 GO:0006000 GO:0006003 GO:0006094 GO:0006096 GO:0008152 GO:0016301 GO:0016310 GO:0016311 GO:0016740 GO:0016787 GO:0019900 GO:0031100 GO:0032868 GO:0033133 GO:0033762 GO:0042594 GO:0042802 GO:0043540 GO:0046835 GO:0051384 GO:0051591 GO:0061621 GO:0070095
3	0.46	0.904	1.70	0.22	0.99	1h2eA
4	0.45	0.848	1.90	0.20	0.94	2axnA	GO:0000166 GO:0003824 GO:0003873 GO:0004331 GO:0005524 GO:0005654 GO:0005829 GO:0006000 GO:0006003 GO:0007420 GO:0008152 GO:0016301 GO:0016310 GO:0016311 GO:0016740 GO:0016787 GO:0046835 GO:0061621
5	0.43	0.842	1.91	0.20	0.94	1bifA	GO:0000166 GO:0003824 GO:0003873 GO:0004331 GO:0005524 GO:0006000 GO:0006003 GO:0008152 GO:0016301 GO:0016310 GO:0016311 GO:0016740 GO:0016787 GO:0046835
6	0.42	0.957	0.88	0.24	0.98	4ij5A	GO:0004647 GO:0006564 GO:0008652 GO:0016311 GO:0016787
7	0.39	0.888	2.14	0.26	0.99	4pzaB	GO:0003824 GO:0008152 GO:0016311 GO:0016787 GO:0050531
8	0.38	0.841	2.27	0.17	0.95	3lg2A	GO:0005634 GO:0005737 GO:0005829 GO:0005975 GO:0016311 GO:0016491 GO:0016787 GO:0042254 GO:0046390 GO:0050278 GO:0055114
9	0.38	0.865	2.45	0.21	0.98	3dcyA	GO:0002931 GO:0003824 GO:0004083 GO:0004331 GO:0005622 GO:0005634 GO:0005737 GO:0005739 GO:0005741 GO:0005829 GO:0006003 GO:0006914 GO:0006915 GO:0006974 GO:0008152 GO:0009410 GO:0010332 GO:0010666 GO:0016311 GO:0016787 GO:0030388 GO:0043069 GO:0043456 GO:0045739 GO:0045820 GO:0060576 GO:0071279 GO:0071456 GO:1901215 GO:1901525 GO:1902153 GO:1903301 GO:1904024 GO:2000378
10	0.37	0.852	2.44	0.19	0.98	1riiA	GO:0003824 GO:0004619 GO:0005829 GO:0005886 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0043456 GO:0046538
11	0.36	0.693	2.27	0.26	0.77	3e9cA	GO:0003824 GO:0004083 GO:0004331 GO:0005634 GO:0005737 GO:0005739 GO:0005741 GO:0005829 GO:0006003 GO:0006914 GO:0006915 GO:0008152 GO:0016311 GO:0016787 GO:0030388
12	0.35	0.846	2.37	0.21	0.98	1fztA	GO:0003824 GO:0004619 GO:0005634 GO:0005829 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0043456 GO:0046538 GO:0061621
13	0.35	0.848	2.23	0.17	0.97	3hjgA	GO:0009236 GO:0016311 GO:0043755
14	0.33	0.855	2.39	0.21	0.98	3r7aB	GO:0004619 GO:0006096
15	0.32	0.758	2.28	0.19	0.85	2p30A	GO:0003824 GO:0008152
16	0.32	0.848	1.94	0.20	0.94	2a6pA
17	0.31	0.849	2.42	0.17	0.98	4embA	GO:0003824 GO:0004619 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0046538
18	0.31	0.850	2.46	0.19	0.98	4eo9A	GO:0003824 GO:0004619 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0046538
19	0.30	0.863	2.33	0.18	0.98	2h4xA	GO:0003824 GO:0004082 GO:0004083 GO:0004619 GO:0005829 GO:0005975 GO:0006006 GO:0006094 GO:0006096 GO:0007585 GO:0008152 GO:0016311 GO:0016787 GO:0016853 GO:0016868 GO:0043456 GO:0046538 GO:0070062
20	0.29	0.841	2.55	0.17	0.98	4odiA	GO:0003824 GO:0004082 GO:0004619 GO:0006096 GO:0008152 GO:0016853 GO:0016868
21	0.29	0.848	2.54	0.16	0.99	1xq9A	GO:0003824 GO:0004619 GO:0005829 GO:0006094 GO:0006096 GO:0008152 GO:0016853 GO:0016868 GO:0043456 GO:0046538
22	0.28	0.838	2.39	0.18	0.97	1qhfA	GO:0003824 GO:0004619 GO:0005737 GO:0005739 GO:0005741 GO:0005758 GO:0005829 GO:0006094 GO:0006096 GO:0008152 GO:0016020 GO:0016853 GO:0016868 GO:0043456 GO:0046538
23	0.27	0.845	2.46	0.16	0.98	3d8hB	GO:0003824 GO:0004619 GO:0006096 GO:0008152 GO:0016853 GO:0016868
24	0.26	0.845	2.43	0.15	0.98	1yjxA	GO:0003824 GO:0004082 GO:0004083 GO:0004619 GO:0005737 GO:0005829 GO:0006094 GO:0006096 GO:0006110 GO:0008152 GO:0016020 GO:0016311 GO:0016787 GO:0016853 GO:0016868 GO:0019901 GO:0043209 GO:0043456 GO:0045730 GO:0046538 GO:0061621 GO:0070062

Consensus prediction of GO terms

Molecular Function	GO:0004331	GO:0005524	GO:0003873	GO:0046538	GO:0004083	GO:0070095	GO:0019900	GO:0042802
GO-Score	0.85	0.71	0.71	0.49	0.48	0.47	0.47	0.47
Biological Processes	GO:0016311	GO:0006003	GO:0006094	GO:0046835	GO:0061621	GO:0006000	GO:0006914	GO:0030388	GO:0006915	GO:0033133	GO:0051384	GO:0031100	GO:0051591	GO:0042594	GO:0032868	GO:0033762	GO:0007420
GO-Score	0.85	0.85	0.73	0.71	0.71	0.71	0.48	0.48	0.48	0.47	0.47	0.47	0.47	0.47	0.47	0.47	0.45
Cellular Component	GO:0005741	GO:0043540	GO:0005654
GO-Score	0.48	0.47	0.45

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0525

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]