Threading Zmax Znorm MUSTER 3.73 0.64 dPPAS 7.89 0.85 wdPPAS 8.91 0.96 wMUSTER 4.15 0.72 wPPAS 6.76 0.97 dPPAS2 14.76 1.41 PPAS 5.27 0.75 Env-PPAS 7.62 0.95 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.71 0.31+-0.10 13.6+-4.0 3140 0.027 model2 -3.83 2645 0.024 model3 -3.93 2429 0.022 model4 -4.58 1283 0.011 model5 -4.51 1374 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).