Threading Zmax Znorm MUSTER 7.06 1.22 dPPAS 9.40 1.01 wdPPAS 21.52 2.31 wMUSTER 10.05 1.73 wPPAS 24.00 3.43 dPPAS2 23.45 2.23 PPAS 13.95 1.99 Env-PPAS 20.83 2.60 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=9279) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.61 0.64+-0.13 7.2+-4.2 6420 0.264 model2 -3.43 638 0.016 model3 -3.71 528 0.012 model4 -3.01 974 0.024 model5 -4.26 253 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).