I-TASSER results

I-TASSER results for job id Rv0421c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (209 residues)
MNLDQIAGVAHQPAGPPHGVVVLTHGAGGSRESTLLQQVCAEWTRRGWLAVRYNLPYRRR
RPTGPPSGSGSGDRAGIVEAIQLCRGLAEGPLIAGGHSYGGRQTSMVVAAGQAPVDVLTL
FSYPVHPPGKPERVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITG
ARHDLGSKTLDVARLAVDAALRLSAGQIA

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MNLDQIAGVAHQPAGPPHGVVVLTHGAGGSRESTLLQQVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGSGDRAGIVEAIQLCRGLAEGPLIAGGHSYGGRQTSMVVAAGQAPVDVLTLFSYPVHPPGKPERVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGARHDLGSKTLDVARLAVDAALRLSAGQIA
Prediction	CCCEEEEEEEHCCCCCCCEEEEEHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHCHHHHHHHHHHHCCCCCCCEEEEHCCCCCCCCCCCCCHHHHHHCCCCCEEEEHCCCCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
Conf.Score	97558999998789998779999689999988889999999999989989997579876677888888645669999999999985799868999877568999999984887776899986999888887555567765689988999859999889999999999879995999988999888887478899999999999999979
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MNLDQIAGVAHQPAGPPHGVVVLTHGAGGSRESTLLQQVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGSGDRAGIVEAIQLCRGLAEGPLIAGGHSYGGRQTSMVVAAGQAPVDVLTLFSYPVHPPGKPERVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGARHDLGSKTLDVARLAVDAALRLSAGQIA
Prediction	75474040203214641200000001110324152023004102634010000102223434443454334322400330041057256330000010101220011014455202000002013323432442134404606110000003404304263045106615561301103413020435445224201430143017417
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCEEEEEEEHCCCCCCCEEEEEHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHCHHHHHHHHHHHCCCCCCCEEEEHCCCCCCCCCCCCCHHHHHHCCCCCEEEEHCCCCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
MNLDQIAGVAHQPAGPPHGVVVLTHGAGGSRESTLLQQVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGSGDRAGIVEAIQLCRGLAEGPLIAGGHSYGGRQTSMVVAAGQAPVDVLTLFSYPVHPPGKPERVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGARHDLGSKTLDVARLAVDAALRLSAGQIA

3trdA

0.19

0.17

0.91

2.07

MUSTER

GPVGQLEVMITRPKGEKSVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNG--VGEVEDLKAVLRWVEHHSQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVFY------EGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHG--------RLIELRELLVRNLA

3trdA

0.18

0.17

0.92

1.98

dPPAS

GPVGQLEVMITRPKGIEKVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNGV-GEVEDLKAVLRWVEHHWSQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA--------

3trdA

0.19

0.17

0.91

2.26

wdPPAS

GPVGQLEVMITRPKGEKSVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNGGEVEDLKAVLRWVEHH---SQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA--------

3trdA

0.19

0.18

0.91

2.68

wMUSTER

GPVGQLEVMITRPKGEKSVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNG--VGEVEDLKAVLRWVEHHSQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNL--------A

3trdA

0.19

0.18

0.91

2.84

wPPAS

IPVGQLEVMITRPKGEKSVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNGV-VEDLKAVLRWVEHHW--SQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNL--------A

3trdA

0.19

0.17

0.91

3.07

dPPAS2

GPVGQLEVMITRPKGIEKVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNG--VGEVEDLKAVLRWVEHHSQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA--------

3trdA

0.19

0.17

0.91

2.73

PPAS

GPVGQLEVMITRPKGIEKVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNG--VGEVEDLKAVLRWVEHHWSQDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA--------

3trdA

0.19

0.17

0.91

3.19

Env-PPAS

GPVGQLEVMITRPKGIEKVTGIICHPHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNG--VGEVEDLKAVLRWVEHHSQDDIWLAGFSFGAYISAKVAYDQK--VAQLISVAPPVF------YEGFASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA--------

2fukA

0.15

0.14

0.94

1.95

MUSTER

GPVGPLDVAVDLPEPVQPVTAIVCHPLGGSMHNKVVTMAARALRELGITVVRFNFRSVGTSAGSFDHG--DGEQDDLRAVAEWVRAQPTDTLWLAGFSFGAYVSLRAAAALE--PQVLISIAPPAGRWDFSDV-------QPPAQWLVIQGDADEIVDPQAVYDWLETLEQQPTLVRMPDTSHFFHRKLIDLRGALQHGVRRWLPATP-

2fukA

0.15

0.14

0.95

1.90

dPPAS

GPVGPLDVAVDLPEPDQPVTAIVCHPEGGSMHNKVVTMAARALRELGITVVRFNFRSVGTSAGSFDHGD-GEQDDLRAVAEWVRAQRPTDTLWLAGFSFGAYVSLRAAAALE--PQVLISIAPPAGRWDFSDV-------QPPAQWLVIQGDADEIVDPQAVYDWLETLEQQPTLVRMPDTSHFFHRKLIDLRGALQHGVRRWLPATP-

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 3 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.65

Estimated TM-score = 0.80±0.09

Estimated RMSD = 4.1±2.8Å

Download Model 2

C-score=0.59

Download Model 3

C-score=-2.33

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3trdA	0.892	0.87	0.183	0.914
2	2wtnB	0.892	1.94	0.161	0.981
3	2fukA	0.881	1.61	0.142	0.938
4	3pf8A	0.860	2.05	0.150	0.957
5	2i3dB	0.850	1.86	0.138	0.923
6	1ve6A	0.846	2.52	0.166	0.981
7	4zwnA	0.838	2.52	0.118	0.976
8	5l8sA	0.838	2.70	0.135	0.990
9	3vdxA1	0.837	2.14	0.179	0.938
10	2y6uA	0.836	2.64	0.107	0.981

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.59	50	1a8uA	BEZ	Rep, Mult	26,27,97,98,99,124,156,183
2	0.06	5	5ct6A	BM0	Rep, Mult	26,27,28,29,33,97,98,183,184
3	0.02	2	1iup0	III	Rep, Mult	145,152,166,171,172,173,174,175,176,177,178,179,180,191,194,195,198,204
4	0.01	1	3muoA	ZPR	Rep, Mult	23,50,95,97,98,122,183,196,200
5	0.01	1	3pfcA	NA	Rep, Mult	105,118,120

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.357	3cn7A	0.741	2.55	0.136	0.861	3.1.1.1	98,154,183
2	0.350	1auoA	0.764	2.51	0.171	0.880	3.1.1.1	98,154,183
3	0.326	1dinA	0.760	3.08	0.186	0.943	3.1.1.45	154,183
4	0.320	1i6wB	0.664	2.81	0.156	0.785	3.1.1.3	98,154,183
5	0.286	2h1iA	0.710	3.18	0.145	0.871	3.1.1.1	32,36,98,124,185
6	0.283	3esbA	0.627	3.65	0.156	0.799	3.1.1.74	98,154,183
7	0.281	3gbsA	0.604	3.49	0.124	0.761	3.1.1.74	98,154,183
8	0.260	3dcnA	0.608	3.69	0.138	0.775	3.1.1.74	98,154,183
9	0.129	1va4A	0.812	2.13	0.179	0.909	3.1.1.2	98
10	0.122	3bf7A	0.781	2.58	0.179	0.909	3.1.-.-	NA
11	0.117	1fj2A	0.766	2.93	0.154	0.919	3.1.4.39	NA
12	0.114	1j1iA	0.800	2.59	0.144	0.928	3.7.1.8	98
13	0.066	1cb7A	0.463	3.64	0.086	0.612	5.4.99.1	81
14	0.060	2ocgA	0.813	2.22	0.155	0.923	3.1.-.-	98,100,154,183
15	0.060	2c7bA	0.810	2.49	0.159	0.933	3.1.1.1	NA
16	0.060	1zoiA	0.811	2.22	0.141	0.914	3.1.1.-	98,154,183
17	0.060	1mt3A	0.823	2.25	0.179	0.933	3.4.11.5	NA
18	0.060	1cqzB	0.786	2.70	0.114	0.923	3.3.2.10,3.3.2.3	NA
19	0.060	1iunB	0.808	2.53	0.122	0.938	3.7.1.9	NA
20	0.060	1a8qA	0.815	1.94	0.159	0.904	1.11.1.10	98,183
21	0.060	1zd3A	0.798	2.76	0.117	0.943	3.3.2.10	NA
22	0.060	2b4kA	0.794	2.90	0.132	0.971	3.1.1.43	154,183
23	0.060	1e5tA	0.796	3.22	0.111	0.990	3.4.21.26	NA
24	0.060	1a88A	0.816	2.17	0.168	0.914	1.11.1.10	154,183
25	0.060	1hlgB	0.840	2.78	0.115	0.995	3.1.1.3	NA
26	0.060	2jbwD	0.811	2.63	0.158	0.962	3.7.1.-	98,183
27	0.060	3e3aB	0.808	2.40	0.139	0.928	1.11.1.-	7,26,28
28	0.060	1k8qA	0.835	2.75	0.106	0.990	3.1.1.3	NA
29	0.060	2pl5A	0.792	3.10	0.119	0.962	2.3.1.31	NA
30	0.060	1cpyA	0.792	3.10	0.083	0.971	3.4.16.5	NA
31	0.060	3nwoA	0.835	2.34	0.115	0.957	3.4.11.5	26,158
32	0.060	1a8sA	0.814	2.03	0.169	0.904	1.11.1.10	98,122,154,183

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.45	0.881	1.61	0.14	0.94	2fukA	GO:0016787
1	0.39	0.868	2.18	0.16	0.98	3hjuA	GO:0004622 GO:0005654 GO:0005737 GO:0005789 GO:0005829 GO:0005886 GO:0006629 GO:0006631 GO:0006633 GO:0006954 GO:0009966 GO:0016020 GO:0016042 GO:0016787 GO:0019369 GO:0019433 GO:0019898 GO:0036155 GO:0042803 GO:0046464 GO:0047372 GO:0050727 GO:0051930 GO:0052689 GO:2000124
2	0.37	0.860	2.05	0.15	0.96	3pf8A	GO:0016787
3	0.31	0.798	2.74	0.14	0.95	4wy5A	GO:0008152 GO:0016787 GO:0052689
4	0.30	0.838	2.13	0.18	0.94	4qesA	GO:0003723 GO:0003824 GO:0004601 GO:0005198 GO:0005576 GO:0005654 GO:0005829 GO:0005886 GO:0016020 GO:0016032 GO:0016491 GO:0017000 GO:0019012 GO:0019061 GO:0019062 GO:0019064 GO:0019065 GO:0019068 GO:0019070 GO:0019072 GO:0019076 GO:0019083 GO:0030666 GO:0030683 GO:0031904 GO:0039573 GO:0039660 GO:0042025 GO:0046761 GO:0055036 GO:0055114 GO:0075733 GO:0098869
5	0.27	0.769	2.80	0.17	0.90	4fhzA	GO:0016787
6	0.27	0.756	2.81	0.14	0.91	1imjA	GO:0005634 GO:0005730 GO:0005737 GO:0005829 GO:0016787 GO:0045944 GO:0050427 GO:0070062
7	0.24	0.849	2.53	0.16	0.99	3o4jC	GO:0005737 GO:0006508 GO:0008236 GO:0016787
8	0.21	0.892	0.87	0.18	0.91	3trdA	GO:0016787
9	0.21	0.800	2.59	0.14	0.93	1j1iA	GO:0016787
10	0.21	0.873	1.79	0.14	0.94	2i3dB	GO:0016787
11	0.19	0.891	1.87	0.16	0.98	2wtmA
12	0.19	0.835	2.34	0.12	0.96	3nwoA	GO:0006508 GO:0008233 GO:0016787
13	0.19	0.808	2.24	0.16	0.91	4dgqA	GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
14	0.19	0.816	2.17	0.17	0.91	1a88A	GO:0003824 GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
15	0.19	0.814	2.86	0.18	0.98	3azoA	GO:0004177 GO:0006508 GO:0008236
16	0.19	0.812	2.10	0.15	0.91	3fobA	GO:0003824 GO:0004601 GO:0009636 GO:0016491 GO:0016691 GO:0016787 GO:0019806 GO:0055114 GO:0098869
17	0.18	0.815	1.94	0.16	0.90	1a8qA	GO:0003824 GO:0004601 GO:0016491 GO:0017000 GO:0055114 GO:0098869
18	0.18	0.812	2.05	0.17	0.90	3heaA	GO:0003824 GO:0004064 GO:0004601 GO:0016491 GO:0016787 GO:0055114 GO:0098869
19	0.18	0.829	2.43	0.15	0.96	2hdwA	GO:0016787
20	0.18	0.832	2.69	0.11	0.98	2y6vC	GO:0004806 GO:0005777 GO:0005782 GO:0007031 GO:0016298 GO:0016787 GO:0019433
21	0.18	0.811	2.22	0.14	0.91	1zoiA
22	0.18	0.805	2.40	0.18	0.92	1hkhA	GO:0003824 GO:0004601 GO:0098869
23	0.17	0.783	3.02	0.13	0.96	4n5hX	GO:0008152 GO:0016787
24	0.12	0.799	3.00	0.13	0.97	4bzwA	GO:0008152 GO:0016787 GO:0042802
25	0.12	0.814	2.03	0.17	0.90	1a8sA	GO:0003824 GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
26	0.11	0.800	2.70	0.16	0.94	1q0rA	GO:0016787 GO:0017000 GO:0052689
27	0.08	0.798	3.08	0.13	0.98	1jkmB	GO:0008152 GO:0016787

Consensus prediction of GO terms

Molecular Function	GO:0003676	GO:0016209	GO:0016684	GO:0005198	GO:0042803	GO:0004622	GO:0047372
GO-Score	0.60	0.60	0.60	0.60	0.39	0.39	0.39
Biological Processes	GO:0039663	GO:1990748	GO:0019049	GO:0046755	GO:0075528	GO:0075509	GO:0046753	GO:0050687	GO:0050690	GO:0019080	GO:0045916	GO:0016999	GO:1902583	GO:0006898	GO:0020012	GO:0032774	GO:0044650	GO:0036155	GO:2000124	GO:0019433	GO:0019369	GO:0006633	GO:0051930
GO-Score	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.39	0.39	0.39	0.39	0.39	0.39
Cellular Component	GO:0033648	GO:0098588	GO:0030659	GO:0098805	GO:0044423	GO:0044440	GO:0005775	GO:0030139	GO:0005829	GO:0005886	GO:0005654	GO:0005789	GO:0019898
GO-Score	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.60	0.57	0.57	0.57	0.39	0.39

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.