I-TASSER results

Input Sequence in FASTA format

>protein (123 residues)
MRPRRALAGLAADVVAVLVFCAVGRRSHAEGLSVTGLAATAWPFLTGTGIGWVLARGWRR
PTALAPTGVIVWLCTIVVGMVLRKVSSAGVAASFVVVASAVTAVLLLGWRAAVALMAPHR
ADG

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MRPRRALAGLAADVVAVLVFCAVGRRSHAEGLSVTGLAATAWPFLTGTGIGWVLARGWRRPTALAPTGVIVWLCTIVVGMVLRKVSSAGVAASFVVVASAVTAVLLLGWRAAVALMAPHRADG
Prediction	CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
Conf.Score	987658999999999999999999998688889999999999999999999999986567765446899999999999999999987988865999999999999999999999998766569
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MRPRRALAGLAADVVAVLVFCAVGRRSHAEGLSVTGLAATAWPFLTGTGIGWVLARGWRRPTALAPTGVIVWLCTIVVGMVLRKVSSAGVAASFVVVASAVTAVLLLGWRAAVALMAPHRADG
Prediction	754542122001122012200100231254523222123033123202321221133344343223200200122233122011135453333013213333333332222012203444678
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120

                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MRPRRALAGLAADVVAVLVFCAVGRRSHAEGLSVTGLAATAWPFLTGTGIGWVLARGWRRPTALAPTGVIVWLCTIVVGMVLRKVSSAGVAASFVVVASAVTAVLLLGWRAAVALMAPHRADG

4k1cA1

0.12

0.11

0.98

1.02

wMUSTER

RAAVYDLQYILKALNFLLVFVPLGLIWGHFQLSFLFNFLAIIPLAAILANATEELADKAGNTIGGLLNATF--NAVELIVSIIALKKGNPHHSSLVILLGTTVIISFCADFLVGTIDNVVESG

4q2eA1

0.14

0.11

0.83

0.96

wPPAS

VS--ESLIGLVSAILILAGYELITLEERDARF-FYVILLALYPVLYGLVF----------------EPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRD--G

4zowA2

0.09

0.08

0.92

1.55

dPPAS2

RTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLK----------

1orsC

0.07

1.00

1.02

wMUSTER

VMEHPLVELGVSYAALLSVIVVVVEYTMQLSGEYLVRLYLVDLILVIILWADYAYRAYGDPAGYVKKTLYEIPALAGLLALIEGHLAGLGLFRLVRLLRFLRILLIISRGSKFLSAIADAADK

2mgyA

0.09

0.08

0.91

0.96

wPPAS

MP-ESWVPAVGLTLVPSLGGFMGAYFVRGE---GLRWYAGRWTLAPIWGTLYSAMGY-GGFTEDAMVPLGLYTGQLALNWAPPIFFGRQMGWALADLLLVSGVATATTLAW-----VSPPA-A

3wdoA2

0.10

0.96

1.55

dPPAS2

L----NFGIMCLHMLLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRKMKQVFVFCVGLIVVAEIVLWNAQTQF-WQLVVGVQLFFVAFNLMEALLPSLISKEGYKG

5a40A

0.13

0.12

0.97

0.98

wMUSTER

YAPLNFIAIGIGATLGAWLRWVLGLKLNGAGW-GTLTANLVGGYLIGVMVALIASHPEWPAWIAAVTGFLGGLFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR---

2oerB

0.08

0.96

1.40

dPPAS2

FPNKAAILFRLQSDEWRRTTRLLGEILEDTTRPPLERLRRLVLAFVRSECEEAAIRVAPLYRDADEAREVKAEGARVFQAFLREALPEVA-----EAERSLAGDLLTTTLGAVGKQFSEQPRS

4xydA2

0.08

0.96

0.98

wMUSTER

----AITNVLLLGLWGLTLLFLFAFYNPSNLALVHLWVEGTWELVMASVLAFLMLKLTGVDREIIEKWLYLIVATALFSGILGTGH-IGTPGYWQWIGSIFSALEVVPFFGMMAFAFVMVWKG

4uc1A

0.09

0.08

0.94

1.36

dPPAS2

MNMD--WALFLTFLAACGAPATTGALLKPDENPPRWVFPLAWTSLYFLMSLAAMRVAQLEG---SGQALAFYAAQLAFNTLWTPVFFGMKRMATALAVVMVMWLFVAATMWAFFQLDTWAG--

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.19

Estimated TM-score = 0.46±0.15

Estimated RMSD = 9.1±4.6Å

Download Model 2

C-score=-3.35

Download Model 3

C-score=-3.53

Download Model 4

C-score=-2.73

Download Model 5

C-score=-3.55

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2jswA	0.696	3.32	0.114	0.984
2	4ryiA	0.692	3.08	0.091	0.951
3	1st6A	0.679	2.73	0.095	0.854
4	4a01A	0.664	3.17	0.066	0.951
5	5cwiA	0.663	3.61	0.058	0.959
6	2x0cA	0.660	2.78	0.101	0.829
7	4uc1A	0.655	3.19	0.122	0.935
8	3ay5A	0.655	3.43	0.133	0.959
9	1ocrN2	0.654	3.50	0.083	0.935
10	4kblA	0.649	3.68	0.042	0.968

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.08	4	1u6hA	III	Rep, Mult	42,45,47,48,49,51,82,95,99,102,110,113
2	0.08	4	5c65A	37X	Rep, Mult	70,104
3	0.04	2	3v2d2	MG	Rep, Mult	106,110
4	0.04	2	1y7iA	SAL	Rep, Mult	54,83,84
5	0.04	2	2ljcA	RIM	Rep, Mult	95,98,99
6	0.04	2	2uxhB	QUE	Rep, Mult	7,10,11,28,50,73,74,77,78,81
7	0.04	2	4ryrA	MPG	Rep, Mult	77,78,85,94,97,98,101
8	0.02	1	1m56G	CA	Rep, Mult	13,16,44,46
9	0.02	1	1g42A	CA	Rep, Mult	66,69
10	0.02	1	3uoiW	HEM	Rep, Mult	72,79,106,110
11	0.02	1	3k7tB	GP7	Rep, Mult	34,36,39
12	0.02	1	2wsc2	CLA	Rep, Mult	47,54
13	0.02	1	2gsmA	CA	Rep, Mult	86,91,93,96,97
14	0.02	1	3ae5C	EPH	Rep, Mult	14,82,85

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.167	3dwwA	0.606	3.48	0.093	0.870	5.3.99.3	50,77
2	0.060	1yqwR	0.610	3.76	0.075	0.919	1.12.2.1	74
3	0.060	2occN	0.599	3.15	0.075	0.813	1.9.3.1	NA
4	0.060	1fgjA	0.588	3.92	0.066	0.862	1.7.3.4	NA
5	0.060	1z8lA	0.567	4.37	0.043	0.935	3.4.17.21	NA
6	0.060	2pnoL	0.641	3.23	0.128	0.886	4.4.1.20	73,106
7	0.060	1b8fA	0.572	3.82	0.060	0.854	4.3.1.3	NA
8	0.060	2ix6E	0.594	3.97	0.075	0.894	1.3.3.6	NA
9	0.060	1cc1L	0.601	3.92	0.049	0.911	1.12.99.6	106
10	0.060	2jifA	0.554	3.77	0.065	0.813	1.3.99.-	NA
11	0.060	3gzhA	0.557	4.28	0.067	0.862	4.3.2.2	NA
12	0.060	2ebaA	0.561	4.07	0.082	0.870	1.3.99.7	NA
13	0.060	3djlA	0.556	4.36	0.067	0.951	1.3.99.-	NA
14	0.060	2uxwA	0.597	3.81	0.087	0.878	1.3.99.-	NA
15	0.060	3b8eC	0.523	4.31	0.046	0.829	3.6.3.9	41
16	0.060	3fedA	0.575	3.94	0.043	0.911	3.4.17.21	NA
17	0.060	2pmzQ	0.466	4.19	0.070	0.756	2.7.7.6	95
18	0.060	2v8tA	0.556	4.50	0.123	0.911	1.11.1.6	NA
19	0.060	1m56A	0.622	3.86	0.082	0.968	1.9.3.1	44
20	0.060	3ii9C	0.579	4.03	0.071	0.886	1.3.99.7	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.17	0.656	3.19	0.12	0.94	5duoA	GO:0005886 GO:0006810 GO:0008289 GO:0016020 GO:0016021 GO:0033013 GO:0046906
1	0.16	0.655	3.34	0.12	0.95	1r0dA	GO:0003779 GO:0005543 GO:0005737 GO:0005856 GO:0005905 GO:0006897 GO:0006898 GO:0006915 GO:0012505 GO:0016020 GO:0030136 GO:0030276 GO:0030665 GO:0031410 GO:0035091 GO:0043231 GO:0048471 GO:0072583
2	0.11	0.696	3.32	0.11	0.98	2jswA	GO:0001726 GO:0003779 GO:0005178 GO:0005200 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0007016 GO:0007044 GO:0007155 GO:0009986 GO:0016020 GO:0017166 GO:0030054 GO:0030274 GO:0030866 GO:0032403 GO:0032587 GO:0042995 GO:0051015 GO:0070062 GO:0070527
3	0.11	0.512	3.44	0.06	0.76	4onsC	GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
4	0.10	0.714	2.83	0.08	0.92	4rymA	GO:0005886 GO:0006810 GO:0016020 GO:0016021 GO:0033013 GO:0046906
5	0.09	0.679	2.73	0.10	0.85	1st6A	GO:0001725 GO:0002009 GO:0002162 GO:0003779 GO:0005198 GO:0005623 GO:0005737 GO:0005743 GO:0005856 GO:0005886 GO:0005903 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005916 GO:0005925 GO:0005927 GO:0007155 GO:0008013 GO:0015629 GO:0016020 GO:0017166 GO:0030018 GO:0030032 GO:0030054 GO:0030334 GO:0030486 GO:0031594 GO:0031625 GO:0034333 GO:0034394 GO:0042383 GO:0042803 GO:0043034 GO:0043234 GO:0043297 GO:0045121 GO:0045294 GO:0045296 GO:0048675 GO:0051015 GO:0051371 GO:0051393 GO:0070062 GO:0070527 GO:0090136 GO:0090636 GO:0090637 GO:0097110 GO:0098723 GO:1903561 GO:1990357
6	0.08	0.641	3.71	0.07	0.96	4av6A	GO:0000287 GO:0004427 GO:0005509 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006814 GO:0009678 GO:0015081 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0030955 GO:0035725 GO:0042803 GO:0046872
7	0.07	0.571	3.95	0.09	0.92	2mgyA	GO:0005497 GO:0005737 GO:0005739 GO:0005741 GO:0006694 GO:0006810 GO:0006811 GO:0006821 GO:0006869 GO:0007268 GO:0007568 GO:0008347 GO:0008503 GO:0010042 GO:0010266 GO:0010823 GO:0010940 GO:0014012 GO:0016020 GO:0016021 GO:0030325 GO:0031397 GO:0031965 GO:0031966 GO:0032570 GO:0032720 GO:0033574 GO:0042493 GO:0043065 GO:0043231 GO:0044325 GO:0045019 GO:0048265 GO:0048266 GO:0048678 GO:0050810 GO:0051901 GO:0051928 GO:0060242 GO:0060252 GO:0060253 GO:0070062 GO:0071222 GO:0071294 GO:0071476 GO:0072655 GO:0072656 GO:0098794 GO:0099565 GO:1903147 GO:1903579 GO:2000379
8	0.07	0.609	3.19	0.09	0.83	4iggB	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034332 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0051015 GO:0051149 GO:0051291 GO:0071681 GO:0090136 GO:0098641 GO:2000146 GO:2001045 GO:2001240 GO:2001241
9	0.07	0.664	3.17	0.07	0.95	4a01A	GO:0004427 GO:0005773 GO:0005774 GO:0006810 GO:0006811 GO:0009678 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0046872 GO:0055085
10	0.07	0.517	3.51	0.05	0.77	4p9tA	GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
11	0.07	0.561	3.91	0.08	0.87	5ic0A	GO:0001726 GO:0003779 GO:0005178 GO:0005200 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0007016 GO:0007044 GO:0007155 GO:0009986 GO:0016020 GO:0017166 GO:0030054 GO:0030274 GO:0030866 GO:0032403 GO:0032587 GO:0042995 GO:0051015 GO:0070062 GO:0070527
12	0.07	0.573	2.73	0.02	0.73	1sj8A	GO:0001726 GO:0003779 GO:0005178 GO:0005200 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0007016 GO:0007044 GO:0007155 GO:0009986 GO:0016020 GO:0017166 GO:0030054 GO:0030274 GO:0030866 GO:0032403 GO:0032587 GO:0042995 GO:0051015 GO:0070062 GO:0070527
13	0.07	0.506	3.27	0.08	0.75	1dowA	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
14	0.07	0.469	4.28	0.05	0.78	4wnlC	GO:0003723 GO:0003729 GO:0005634 GO:0005737 GO:0005789 GO:0005934 GO:0006810 GO:0007533 GO:0008289 GO:0008298 GO:0051028
15	0.07	0.546	2.76	0.05	0.71	4k1nA	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
16	0.07	0.661	3.16	0.07	0.94	4av3B	GO:0000287 GO:0004427 GO:0005509 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006814 GO:0009678 GO:0015081 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0030955 GO:0035725 GO:0042803 GO:0046872
17	0.07	0.475	4.05	0.07	0.74	3mdsA	GO:0004784 GO:0006801 GO:0016491 GO:0019430 GO:0046872 GO:0055114
18	0.07	0.468	3.97	0.05	0.72	1rccA	GO:0005623 GO:0006826 GO:0006879 GO:0008199 GO:0046872

Consensus prediction of GO terms

Molecular Function	GO:0008092	GO:1901363	GO:0097159	GO:0032403
GO-Score	0.51	0.48	0.48	0.41
Biological Processes	GO:1901564	GO:0046483	GO:0006725	GO:1901360	GO:0022610	GO:0012501	GO:0006897
GO-Score	0.51	0.51	0.51	0.51	0.41	0.33	0.33
Cellular Component	GO:0005886	GO:0031224	GO:0005856	GO:0098589	GO:0030662	GO:0012505
GO-Score	0.41	0.40	0.33	0.33	0.33	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0401

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]