Threading Zmax Znorm MUSTER 3.72 0.64 dPPAS 7.86 0.85 wdPPAS 6.04 0.65 wMUSTER 3.75 0.65 wPPAS 4.69 0.67 dPPAS2 13.79 1.31 PPAS 6.52 0.93 Env-PPAS 5.74 0.72 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11034) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.11 0.36+-0.12 13.5+-4.0 1237 0.055 model2 -4.79 915 0.010 model3 -4.78 745 0.010 model4 -5.00 423 0.005 model5 -5.00 302 0.006 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).